Amanda Lund Lab

the Laboratory of Lymphatic Immunobiology - exploring the contribution of lymphatic transport to dermal and anti-tumor immunity @nyulangone

[Anirban Maitra @Aiims1742]

Congratulations Luiz Geraldo for his continuing excellence & winning the @sitcancer 2026 Presidential Award for his work on improving immune surveillance in #glioblastoma.
And to his super mentor @theLundLab!
@Perlmutter_CC @nyugrossman #SITC26

[Itai Yanai @ItaiYanai]

🔥 In our new BioRxiv preprint we show how cancer cell adaptations along a proliferation–robustness axis drive TME pro-tumor phenotypes.
In this work, we asked whether cancer cell states are a result of a physiological response or adaptation to their microenvironment?
To study this, we performed long-term (36 weeks) co-culture experiments with cancer cells evolving alongside continuously replenished fibroblasts or macrophages.
This allowed us to distinguish between adaptive and physiological responses in specific cancer-TME interactions, which we then also recapitulated in patient tumors.
We found that co-culture with fibroblasts induced the epithelial-mesenchymal transition in cancer cells and resulted in their increased drug tolerance, while co-culture with macrophages promoted stress, hypoxia responses and enhanced tumorigenicity.
Adaptations were recurrent and partially reversible, but could not be explained by clonal selection, suggesting a dynamic non-mutational process.
Moreover, adapted cancer cells elicited cell state changes in the fibroblasts and macrophages consistent with an extended phenotype mode of cancer evolution.
Tremendous work by postdoctoral fellow Dr. Maayan Pour!
https://t.co/2PNjZuP6bz

[Dan Landau @landau_lab]

Faculty ad is out,

please help spread the word

Come #DreamBig together, without a doubt,

in the best city in the world!

https://t.co/dhSlHbbfJ0

[Waggoner Lab @LabWaggoner]

Lymph node lymphangiogenesis encapsulates activating germinal centers to constrain their size, which enhances clonal selection and protective antibody responses @ImmunityCP
https://t.co/atX7MBQaMe @nyugrossman @theLundLab

[Amanda Lund Lab @theLundLab]

💡 What sets the size of a germinal center? — why lymphatics of course 😉

Our new study with Carla Nowosad reveals how lymphatic remodeling constrains germinal center growth and shapes the quality of the antibody response. @ImmunityCP @nyugrossman

https://t.co/g1RXqZ1tc7

[Amanda Lund Lab @theLundLab]

Congratulations to Luiz Geraldo who received the new IGNITE award from the @CancerResearch to support his innovative work on glioblastoma immunity. It is such a pleasure to work with Luiz and I am very excited to see where this takes him!! Very well deserved - @Perlmutter_CC

[NYU Grossman School of Medicine @nyugrossman]

Why does immunotherapy fail in brain tumors?

@CancerResearch Ignite Fellow Luiz Geraldo, MD, PhD, is finding out by studying how immune cells access the brain to unlock new treatments for glioblastoma.

Watch ⤵️

Featuring @theLundLab

[Fusion Conferences @Fusion_Conf]

We have had a fantastic first & second day at the #CancerImmuno Conference filled with discussions, networking and cutting edge research.
Cancerimmuno 2026! 🇵🇹

[Fusion Conferences @Fusion_Conf]

The #CancerImmuno conference is packed with four days of opportunities to connect, learn, and share inspiring research.
This year's programme features:
• 2 panel discussions • 2 group activities • 2 hosted networking dinners • 2 poster sessions

[Amanda Lund Lab @theLundLab]

An interesting initiative to use AI to evaluate the validity and rigor of scientific claims and identify gaps in your data and logic. Our collaborative preprint with Carla Nowosad, led by Tenny Mudianto, is highlighted as one of the top 1%!

https://t.co/hVc98WnM4z

[Amanda Lund Lab @theLundLab]

Last day to vote for new SITC Leadership!

[Society for Immunotherapy of Cancer @sitcancer]

The 2026 SITC Election closes tomorrow at 11:59 p.m. EDT! SITC regular and emeritus members (current in dues) can vote at https://t.co/qFSNpJwES8

[Society for Immunotherapy of Cancer @sitcancer]

Learn about 2026 SITC At-Large Director candidate, Amanda W. Lund, PhD (NYU Grossman School of Medicine). Read Dr. Lund’s bio and position statement: https://t.co/kaXEXUeCbt

[Inés Delclaux @InesDelclaux]

Excited to share the preprint of my thesis work, where we've uncovered a continuous lymphatic circuit that recycles tumor-experienced T cells to sustain anti-tumor immunity — with implications for cancer immunotherapy. https://t.co/0JQDTi9936

Ty to @theLundLab and coauthors!

[Amanda Lund Lab @theLundLab]

New #LundLab preprint from @InesDelclaux ! She shows that the chronicity of the anti-tumor T cell response is fueled in part by continuous T cell migration and functional lymphatic transport. 👇https://t.co/S8ycUUnbEg

[Society for Immunotherapy of Cancer @sitcancer]

The 2026 SITC Election is now open! SITC members are electing the society’s next Vice President, Secretary/Treasurer and three At-Large Directors. The election closes on Friday, May 15 at 11:59 p.m. EDT. https://t.co/qFSNpJwES8

[Delgoffe Lab @DelgoffeLab]

Dearest gentle reader, we are delighted to announce a new story from our lab published in @Nature describing how a meal's systemic metabolic changes are interpreted by your immune system to enhance adaptive immunity. A thread 1/ https://t.co/zACqCLxDMU

[Society for Immunotherapy of Cancer @sitcancer]

The #SITC election starts on Friday! The three At-Large Directors who receive the plurality of votes will begin three-year terms in 2027. Read the biographies and platform statements of this year’s candidates at https://t.co/cU4J1YxyMp

[Amanda Lund Lab @theLundLab]

Honored to be nominated for an At-Large Director position on the SITC Board. I'm excited by the opportunity to give back, support their mission, and help to continue pushing the science - and the community - forward #SITC

https://t.co/aEHfq0M91M

[Society for Immunotherapy of Cancer @sitcancer]

Announcing your candidates for the 2026 SITC Election! From May 1–15, SITC members will vote to elect the next leaders of the society. Read the biography and platform statement of each candidate here: https://t.co/qFSNpJwES8

[Fusion Conferences @Fusion_Conf]

📢This is your last chance to register for #CancerImmuno conference!📢
Be quick - only a few spaces remaining!
For more information email Felicity ([email protected]) or click here to visit the conference website: https://t.co/BP40Q5cSpJ
We look forward to welcoming you to Portugal soon!🌞🇵🇹
#FusionImmunology #FusionCancerResearch

[Fusion Conferences @Fusion_Conf]

#CancerImmuno Announcement📢
📅Final deadline closing this week (Thursday 16th April 2026, BST!) This is your last opportunity to register and join us at the conference!
Register now! we look forward to welcoming you to Portugal soon! 🇵🇹🌞
🔗https://t.co/dHZRwp9eng