Rick Baker

Assistant Prof @UNC, @UNC_BCBP, #cryoEM, membrane trafficking, views my own

[Rick Baker @therickybaker]

@intspg @ATinyGreenCell haha I love this!

[Rick Baker @therickybaker]

We are struggling to identify these class averages in a #cryoEM dataset. Does anyone recognize this protein complex from E. coli? Looks to be C2. Doesn't look like the usual culprits (ArnA, GroEL, Catalase, etc.). Sadly preferred orientation so can't get a useful map

[Intrepid Sponge 𐇐𐇑𐇒𐇓𐇔𐇕𐇖𐇗𐇘𐇙𐇚 @intspg]

@therickybaker @ATinyGreenCell

[Rick Baker @therickybaker]

@BigwetRealism @ATinyGreenCell It is ODO1: 2-oxoglutarate dehydrogenase(E1).

[Rick Baker @therickybaker]

@ATinyGreenCell haha I did actually and it said GroEL or proteasome :/

Another person identified it: Turns out it is ODO1: 2-oxoglutarate dehydrogenase(E1).

[Rick Baker @therickybaker]

@CryoHuntington @ImagingArtifact This is it! Thanks for solving this mystery

[Rick Baker @therickybaker]

@BigwetRealism @ATinyGreenCell too small, probably. but I can see it!

[Rick Baker @therickybaker]

Lmao

[Andrew White 🐦‍⬛ @andrewwhite01]

After two years of work, we’ve made an AI Scientist that runs for days and makes genuine discoveries. Working with external collaborators, we report seven externally validated discoveries across multiple fields. It is available right now for anyone to use. 1/5

[Rick Baker @therickybaker]

I was lucky to see this work over the past year. Awesome work by @AbidKhanEpigen , @DrBrianStrahl, and colleagues only SETD2 and it's novel interaction with nuclear lamin. Very intriguing and many cool questions left to answer!

[Abid Khan @AbidKhanEpigen]

🚨 Thrilled to share my latest work from the @DrBrianStrahl lab—out now in @NatureCellBio! We reveal the first non-catalytic role of the histone methyltransferase SETD2, showing it moonlights in mitosis to preserve nuclear and genome integrity.

[Rick Baker @therickybaker]

@peiferlabunc Tenure packet due Nov 1 🥲🥲 (although this is only the college so far, right?). Very upsetting

[Rick Baker @therickybaker]

@aleschziner Also, data preservation for the win! Still have these frames 7 years later even though we never published this data

[Rick Baker @therickybaker]

Reprocessing some old #cryoEM data from my time in @aleschziner lab. Gonna use this to prove to my students that I used to be awesome in the lab!
2.7 Å from 550 micros, hand-selected in Leginon and collected in super-res (gasp!) on a Talos with a K2. Ancient by today's standards

[Juan S. Bonifacino @BonifacinoJuan]

Our lab at the NIH (Bethesda, MD) is looking for postdocs to join our team studying the molecular mechanisms of protein trafficking and their links to neurodevelopmental disorders starting on or after 10-1-2025. Send your application to [email protected]. Please repost!

[Ming Li Lab@Umich @MingLi_Umich]

A great opportunity to join a legendary lab.

[UNC Biochemistry and Biophysics department @UNC_BCBP]

Congrats to Dillon Sloan, UNC SOM Biochemistry and Biophysics grad student in the Rick Baker lab, for earning an NIH Fellowship (F31) from the National Institute of Dental and Craniofacial Research

[Rick Baker @therickybaker]

@bluesocks81 Amazing! Thanks!

[Rick Baker @therickybaker]

@UNC_Optics @SAPConcur @DOGE I think I misread this earlier. Bc the trip isn’t available in Concur, you can’t submit the proof of a cost savings for the exact itinerary, so you have to b it the more expensive route on Concur?

[Rick Baker @therickybaker]

I’ll be there!

[Rebecca Berlow @BerlowLab]

Coming to #BPS2025? Please attend the CPOW-sponsored workshop "Managing It All: Making Time for Success" on Monday, Feb. 17 at 2:30pm in Room 403B! Come learn how to maximize your productivity and build your time & project management skills! Open to ALL attendees. @BiophysicalSoc

[John Streicher @JohnStreicher1]

Can I give some unsolicited advice? When communicating on this catastrophe, don’t lead with “I know the NIH is inefficient and needs serious reform, but…”. You are undercutting the entire message and buying into the frame of the arsonists. This is not a scientist audience.