TB

[Nura Bio @nurabio_]

As Nura Bio marches towards transformative neuroprotective therapies for patients, we'd like to pause for a moment to acknowledge the tremendous contributions of our team and the unwavering support of our investors and advisors. Together, we’re making crucial strides towards new treatments for neurological diseases. Learn more: https://t.co/7xSKoy4IEx

🚀 Nura Bio has added $68M to the initial $73M series A raise in 2020, bringing the total raise to $140M+. This funding will advance a pipeline of neuroprotective therapies.

🧠 Brain-penetrant SARM1 inhibitor, NB-4746, completed a successful Phase 1 study in healthy volunteers.

🌟 Shilpa Sambashivan, Ph.D., CSO and founding team member, assumes reins as CEO, leading the team in translating groundbreaking research into potential therapies.

#Biotech #Neuroscience #SARM1

[TB @tommyburd]

@patrickc They aren’t against wind and solar in and of themselves. They are against subsidizing something that is inefficient for providing baseload power. They are against the narrative that in total they are cleaner or better environmentally then alternatives

[TB @tommyburd]

@mumumouse2 Best defense - plotting software from unique instrumentation exports in odd formats. Import to Illustrator to make figure and line break artifacts are introduced that are not visible until you increase line weight. it’s really not acceptable in a final figure though.

[TB @tommyburd]

@ATinyGreenCell Where do you get the plugs for the conical tubes?

[TB @tommyburd]

@micsolana

[TB @tommyburd]

@maphumanintent If self driving cars/RVs/trucks are on deck for the next few years, why would we ever build more passenger rail?

[TB @tommyburd]

@sjoshimd LOL

[TB @tommyburd]

@BostonGlobe No. Stop it.

[TB @tommyburd]

@boston25 Stop testing.

[TB @tommyburd]

@statnews What is the goal here? Testing has made zero impact on COVID. Everyone had COVID or has been vaccinated. Testing will just lead to needless unnecessary disruption.

[TB @tommyburd]

@MonicaGandhi9 Honestly. Only delusional people thought it was a good idea to mask kids. You only had to watch a masked kid for 30 seconds to understand this was never going to do anything.

[TB @tommyburd]

@brendan_49 @HealthcareNinj1 > anemia
> this shouldn’t hold readthrough to their (transport vehicle) platform as a whole, but instead is the product of the combination of TREM2 and TfR1 which elicits an immune response that has an impact on transferrin function
https://t.co/ILyui4LdQN

[TB @tommyburd]

@brendan_49 @HealthcareNinj1 $DNLI TREM2 antibody DNL919 was just discontinued:
"In the Phase 1 study, DNL919 - demonstrated changes in CSF biomarkers - safety signals of moderate, reversible hematologic effects at the highest dose - believed to be specific to properties of DNL919 and TREM2 biology."

[TB @tommyburd]

@PearlF @jeff_cranmer @BioCentury There are also multiple completely fraudulent companies trading at > $500 million market cap.

[TB @tommyburd]

@kevinnbass You should read some public choice theory. Public health serves public health…

[TB @tommyburd]

@dylanleclair @GeorgeGammon @LukeMikic21 @SantiagoAuFund Von Havenstein agrees!

[TB @tommyburd]

@FloydZhang93 @Nature It’s called Trump Derangement Syndrome. Main symptoms are abandonment of evidence based inquiry for full blown hyperventilating emotional outbursts. Scientists were particularly susceptible.

[TB @tommyburd]

@DrScottBalsitis https://t.co/QhLlYe04Qq

[TB @tommyburd]

@Todd_Friesen This would imply that modest efficacy (~15% as you posit) leads large effect sizes. As such effect size would be easily observable in both RCTs, observational trials, and in geographic regions with different policies. Except large effect sizes are not observed. Why?

[TB @tommyburd]

@GidMK LOL… the claim a few years ago was that the entire pandemic could be ended of selfish people just wore a cloth mask.

[TB @tommyburd]

@arampell @1nternetjack So many people ask me why I can’t stop with the mask debate. I watched my two year old hate pre-school and not want to do other activities like CalAcademy because it meant wearing a saliva soaked mask. Completely worthless, but I fear they will try to mask kids again - We left CA