Last night an AI agent performed brain surgery on a mouse.
We gave it 19 gene therapy vectors in a spreadsheet, a mouse model of epilepsy, access to a motorize surgery rig with cameras and one goal: reduce seizures.
It picked the drug. It picked the brain region. It derived the coordinates from three papers. Then it drove the stereotaxic arms into the brain and injected 250 nanolitres while watching the entry site through the rig camera for bleeding.
A licensed vet gated every irreversible step and held a physical kill switch to stop the AI agent.
Thread on what it decided, what it saw, and the moment it refused to let me override it.
[Writing this on the spot out of excitement, but I've been 18hrs in front of my laptop coding and coordinating this, so keeping it brief and descriptive, more cohesive thoughts on this soon...]
My dear friends, I’d like to show you my latest toy project
Introducing Handwired: turn your regular JavaScript code into a neural net!
- no training
- exact outputs vs the JS program
- fully differentiable
All runnable in a browser, without GPU
After co-inventing ChatGPT, I kept asking myself: why have superhuman chat models not led to AGI?
I’ve spent the last 2 years in stealth building a new way to train models (RLCD), and a new type of frontier AI model that we are releasing today: Jev
• 20-200x faster
• 40-400x cheaper (w/ output tokens free)
• Frontier composable intelligence optimized for decisions
AFAICT the shortest path to AI-based economic revolution
Hello, Moon. It’s great to be back.
Here’s a taste of what the Artemis II astronauts photographed during their flight around the Moon. Check out more photos from the mission: https://t.co/rzM1P0QbOl
Hippo fluid scene pushed to 100M particles made with HydroFX. Foam, bubbles, and spray all simmed together in one system for a cohesive result, fully GPU accelerated. Meshed + extra sand interaction in Houdini, final lookdev/render in Blender. Get HydroFX https://t.co/1aKDxmZK9V
My dear front-end developers (and anyone who’s interested in the future of interfaces):
I have crawled through depths of hell to bring you, for the foreseeable years, one of the more important foundational pieces of UI engineering (if not in implementation then certainly at least in concept):
Fast, accurate and comprehensive userland text measurement algorithm in pure TypeScript, usable for laying out entire web pages without CSS, bypassing DOM measurements and reflow
Here is one of the graphics Filippo Biondi shared with Matt Beall regarding where he believes they have discovered a 2nd Sphinx buried under Giza. The red circle on the right is where the Great Sphinx is located & the circle on the left is where they believe this 2nd Sphinx is hidden - if you zoom in you can see a mound… Based on this location, they believe they have found 100% precise geometric correlation to 1st Sphinx.
See Matt’s interview here https://t.co/87BqKULuQP
NEW VIDEO: The Egg
A Big Thanks to @andyweirauthor for allowing us to use his story.
This video was more than 2 years in the making and is a little bit different than the others on this channel. We hope you like it.
https://t.co/syb9NB0Ker