TuguesLab

Immunology Research Lab @UZH_en 🔬 Studying the Interplay between Innate Lymphoid Cells (ILCs) and Cancer

[Marijne Vermeer @marijnevermeer]

Excited to share our new study out in @NatureComms ! 🎉 We show that NK cell localization in the lung determines their ability to eliminate tumor cells.

🫁 https://t.co/cz4Aee4lJa

[Journal of Experimental Medicine @JExpMed]

Myers, Reilly, & Brossay @BrownUniversity discuss work by @csparano93, @SolisSayago et al. @TuguesLab (https://t.co/FnvUP9BlDu) which shows that tissue-resident NK cells produce TGF-β1 themselves to establish and maintain residency in glandular tissues. https://t.co/ecrhjVIrzH

[Journal of Experimental Medicine @JExpMed]

Autocrine TGF-β1 drives tissue-specific differentiation and function of resident NK cells, say Colin Sparano (@csparano93), Darío Solís-Sayago (@SolisSayago), Sonia Tugues @TuguesLab and colleagues @UZH_en: https://t.co/TytdiQPJ4z

#InnateImmunity #LymphocyteBiology

[Colin Sparano @csparano93]

Excited to share our new paper in @JExpMed 🎉 We show that NK cells use autocrine TGF-β1 signalling to establish tissue residency, form a highly cytotoxic subset, and protect the tissue against viral persistence. https://t.co/EkLtWAPWZo

[Alex Weber, immunologist researcher in Tübingen @Innate_immuno]

Visit the Novel Concepts in #Innate_immunity #Conferences website to submit an abstract and see a list of confirmed speakers, e.g. @BrunoLemaitre3, @laoneill111, @AudeBer, @ClareBryant13, @v_hornung, @LabLeibundgut, @LennonLab, @lloyd_lab, @rosa_paolicelli, @SarrisLab, @TuguesLab

[Nicolò Coianiz @NCoianiz]

I had a good time in Lyon at my first "NK&ILC Meeting"; great science, talks and people!

Thanks to the German Society of Immunology (@dgfi_org) for having gathered all these amazing scientists from around the world.

@TuguesLab

[Cerwenka Lab @CerwenkaLab]

New position is open! Cerwenka and Tugues lab will work together on innate lymphocyte responses in metastatic melanoma and immunotherapy

[HoLab @PCHo_Lab]

Looking forward to visit Zurich next week🫶 Please come to give us some comments for our T cell exhaustion project which I am super excited about🫡

[TuguesLab @TuguesLab]

@DergunStanislav Good luck with the new beginning Stan! You will be missed here!

[TuguesLab @TuguesLab]

Thrilled to share our latest collaboration with @Becherlab: "IL-23 stabilizes effector Treg program in tumors" by @WertheimerT and @PascaleZwicky et al. out now in @NatImmunol. Check out the great tweetorial of the @Becherlab !

[Can Ulutekin @UlutekinCan]

B cell depleting therapies effectively treat #MultipleSclerosis, yet our understanding of why remains limited. How does loss of B cells impact the immune system in MS? See our multicohort study employing high-dimensional single-cell immunophenotyping: https://t.co/C7OLO1IduT

[Felix Wensveen @FMWensveen]

Now out in Science Immunology! Our work on how metabolic stress of hepatocytes triggers inflammation in NASH. First clues for a non-invasive biomarker for the disease in humans https://t.co/ankFqdRgAq

[Tobias Wertheimer @WertheimerT]

Excited to share our work on Tregs in the TME at this fantastic conference #CICON23! @BecherLab @TuguesLab @PascaleZwicky @AACR @ENCI_network @CancerResearch

[TuguesLab @TuguesLab]

Enjoyed a wonderful meeting in Würzburg! Thank you for bringing together so many great people from the NK and ILC community @GeorgGasteiger

[Georg Gasteiger @GeorgGasteiger]

Tissue Homeostasis, Immunity, ILCs+NK cells in a historic winery! June 20-23 in Würzburg -slots filling quickly, abstracts due May 8th -sign up now https://t.co/4UL7S1v58T @Wue_SI and join
@RMedzhitov, @bart_lambrecht, @SunLab_Official, @EricVivier1, @LMackayLab, @Molofsky_lab...

[TuguesLab @TuguesLab]

@DrJHSchroeder @globalimmuno Thanks! Indeed, quite interesting to see this costimulatory marker on ILC1s (we see it specifically on these early, "helper-like" ILC1s but also on immature NK cells). We don't know it's relevance but some old studies suggest on NKs it's functional and can induce proliferation.

[Global Immunotalks @globalimmuno]

Please ask questions for today's Global Immunotalk by Dr. Sonia Tugues HERE by replying to this tweet. Don't forget to mention #globalimmuno.

Sonia will use the account @TuguesLab to answer questions.

[Global Immunotalks @globalimmuno]

Looking forward to our next #globalimmuno talk this Wednesday, May 3rd at 9am PST, noon EST, 4pm GMT by Dr. Sonia Tugues.

Title: “Ontogeny and anti-metastatic function of group 1 innate lymphocytes”
LINK: https://t.co/2Tdtm2yO3d

[TuguesLab @TuguesLab]

@GeorgGasteiger @dgfi_org @RomagnaniLab @DiefenbachLab @CerwenkaLab @Wue_SI @timotheus_halim @JBoettcherLab @GMWiedemann Thank you for organising, we are very much looking forward!

[Georg Gasteiger @GeorgGasteiger]

Interested in Tissue Homeostasis and Immunity? NK cells and ILCs? join this fantastic https://t.co/4UL7S1v58T with lots of exciting science from @SunLab_Official, @EricVivier1, @maini_lab, @LMackayLab, @bjorkstrom_lab, @Molofsky_lab, @Hepworth_Lab...

[TuguesLab @TuguesLab]

@obrunomarcel @fmrp_usp Congratulations Bruno!