Bruno Marcel, PhD

Immunologist/postdoc @fmrpusp He/Him 🇧🇷🏳️‍🌈

[Immunity @ImmunityCP]

Online now: Lysosomal dysfunction drives a transcriptional and epigenetic signature found in disease-associated microglia in neurodegenerative diseases https://t.co/lVx4cjCoEs

[Immunity @ImmunityCP]

Online now: TCR origin and specificity to environmental or self-antigens on distinct antigen-presenting cells determine peripheral Treg cell differentiation https://t.co/gm0NNb194p

[Florian Ingelfinger @FlorianIngelfi1]

Check out our most recent work about a new programmable immunotherapy for MS! It was such a pleasure working with the most talented @Rotem_Shalita, Maya, Chamutal and colleagues from the @IdoAmitLab! Big thanks also to our fantastic collaborators for making this possible!

[Nature Rev Immunol @NatRevImmunol]

Macrophages are constitutive architects of tissue integrity https://t.co/QG4QCjUJV6

[Immunity @ImmunityCP]

Online now: Antigen-restricted Candida albicans Th17 cells link oral-gut immunity and adopt pathogenic features during intestinal inflammation https://t.co/mHqJciC2W8

[SBI - Imunologia @sbi_imuno]

📢 Estão abertas as inscrições para a 1ª IUIS Pan-American Leadership Academy for Early-Career Immunologists

🔗 Para mais informações e inscrições, acesse: https://t.co/drebP4jqKL

[Immunity @ImmunityCP]

Online now: Nasal immunity in respiratory viral infection, transmission, and protection https://t.co/w5b6O7kQWV

[nature @Nature]

Nature research paper: Identification of cross-stage, cross-species malaria CD8+ T cell antigens

https://t.co/W9rJtdbE9S

[Satchin Panda @SatchinPanda]

Adipose or fat tissue is far more than a fat depot—it acts as a metabolic command center, coordinating whole-body health through hormones, metabolites, extracellular vesicles, and neural circuits. When these signaling networks break down with aging or disease, metabolic dysfunction follows. #Metabolism #Aging #PrecisionMedicine
https://t.co/FASOnWFR7D

[Kuchroo Lab @KuchrooLab]

💫Back2back papers in @ImmunityCP led by #DandanYang: multi-omics studies reveal how the gluococorticoid (GC) pathway restrains Th17 cell pathogenicity.
GC steroid synthesis & sensing maintain the homeostatic state of Th17 cells. @AnaAndersonLab
1/3 🧵
https://t.co/BS2oUXNYiE

[Immunity @ImmunityCP]

Online now: Interleukin 23 promotes a pro-inflammatory Th17 cell state by stabilizing RORγt and suppressing glucocorticoid receptor activity https://t.co/jcLztxv1rZ

[The Nobel Prize @NobelPrize]

"Find your own way of functioning... I struggled for the first year and a half as an undergraduate... but I developed my own ways of learning things.

So I advise students, find your own way and your own directions that you can be successful in."

- Physics laureate Kip Thorne

[Immunity @ImmunityCP]

Online now: A longitudinal atlas of human psoriatic skin reveals the mechanisms of anti-IL-23 therapy in disrupting the type 17 inflammatory circuit https://t.co/GfJ8p4ZOjv

[Prof. Akiko Iwasaki @VirusesImmunity]

Excited to share our study by @keylas3 et al. on pathological autoantibodies in people with Long COVID. We asked whether IgG in patients with Long COVID bind to human tissues/antigens and cause pathologies when transferred into mice. With @PutrinoLab

https://t.co/tcowCufWyf

[Gabriele Zaffagnini @zaffagg3]

How flow cytometry works

[Waggoner Lab @LabWaggoner]

Review @NatImmunol @levy_o
Immune development in early life
https://t.co/ZPCMC6S877

[Juan Villar-Vesga @VillarVesga]

Excited to share our new study out in
@SciImmunology
We show that Monocyte-derived Macrophages drive oxidative damage during neuroinflammation
https://t.co/eGKEMppR9y

[Ai Ing Lim @AiingLim]

LIMmunity 2nd brew !!
Motherhood comes with superpower: pathogen protection!

https://t.co/DrmNdBgYjY

We often think moms are immunologically vulnerable to tolerate the baby. But I always wondered: why would evolution make such a critical period of life so dangerous?

[Waggoner Lab @LabWaggoner]

The Foxp3 transcription factor integrates cell-intrinsic and environmental contexts with epigenetic programs to establish regulatory T cell identity @SciImmunology
https://t.co/cMfcuJAnWH
https://t.co/AuIjHkmTqF 🇯🇵

[The Colonna Lab @TheColonnaLab]

What defines human pDC diversity? Our newest work led by @UlezkoAlina in @ImmunityCP uncovers a complex landscape shaped by age and tissue niche, including a cycling pDC subset that declines with age but persists in the BM & expands in malignant BPDCN. https://t.co/O0UJ5O02sa