Our preprint on the first glimpse of how the human proteasome recognizes a K11/K48-branched ubiquitin chain is out. This work reveals a new multivalent ubiquitin binding mode by the proteasome that could serve as priority checkin signal for proteolysis.
https://t.co/Sk2ERBDb9B
A new approach from @_Murphy_Lab@zoliviapg@FilipPetegem and colleagues enables elemental mapping in macromolecular complexes, by combining electron energy-loss spectroscopy with single-particle cryo-EM image processing tools.
https://t.co/VdgVDpfMWp
Check out our game, DEGRADATOR! ๐ฎ Designed to popularize and educate on the ubiquitin-proteasome system and PROTACs. Perfect for kids 12+ but not only ๐ Dive into 10 fun levels to explore protein degradation. Available on Google Play and https://t.co/TMiwcfLi9M ๐
Impressive results at 100keV from Chriss Russo group at MRC, LMB. Look at no. of particles, and micrographs and resolution achieved. A majority of the structures (7 of 11) extended to beyond physical Nyquist resolution. https://t.co/qN82e3jOgd
#MaxPlanck Art & Science Day - for everyone interested in #science & #art! What is #autophagy? How do our cells recycle their waste? How is research communicated via art? Visit us, learn, explore, be creative! With @DoroteaArt, Ayelen Valko, @ArtSci_ARP!
๐https://t.co/SeqLpYYEsA
@MPIbp@Mel_McDowell22 @MSCActions @EU_Commission I want to thank our institute's senior advisor Ulrike Trojahn for the Research Grants application, and definitely, Melanie @Mel_McDowell22, who gave me great support to make this happen!!!