UCL APS Research

Official twitter account of the @UCL Antiphospholipid syndrome research group We cannot give out medical advice via Twitter

[Jason S Knight @jasonsknight]

🕸️👀
This is a smart data/review hybrid paper by the great Pier Luigi Meroni and colleagues...

Beta 2 glycoprotein I and neutrophil extracellular traps: Potential bridge between innate and adaptive immunity in anti-phospholipid syndrome
https://t.co/bAZDAm6M09

[The Lancet Rheumatology @TheLancetRheum]

NEW RESEARCH—Rituximab-treated patients during various phases of the #COVID19 pandemic in the UK.

Severe COVID19 outcomes were similar to other severe infections, and numbers of comorbidities and hypogammaglobulinaemia were predictors of severe outcomes
https://t.co/BVGDqcWnU4

[UCL Rheumatology for Adolescents and Young Adults @UCL_RheumAYA]

We are really excited to share with you this recent publication! Many thanks to everyone who participated. https://t.co/btWIZL2WMg

[Lizzy Rosser @bcells_rosser]

An important comment from my closest collaborators 💎

[laura mccoy @RealMcCoyLab]

Interested in joining us to understand antibodies in systemic amyloidosis? Ideal for anyone interested in single B cell cloning and FACS. Post doc/ RA role available @DoM_UCL together with my lab @iit_ucl @UCLInfectImm https://t.co/2Fbplgq9Dv

[Medical Research Foundation @MedResFdn]

🎉Congratulations to our #Lupus 2022 #EmergingLeadersPrize winners! 🎉

🏆 Dr Alex Clarke @a_j_clarke @ndorms @UniofOxford

🏆 Dr Eve Smith @evemdsmith_eve @livuniHLS @livuniilcams @LivUni @AlderHey

🏆 Dr Thomas McDonnell @ucl @UCLBiochemEng1

[Lizzy Rosser @bcells_rosser]

Today a life-long dream came true ✨ the first official day of the Rosser lab ✨ This dream is funded by a senior research fellowship from @TheKennedyTrust. We got off to a great start.. listening to fascinating talks @TheCrick #LondonInfectImmun. Read more about the lab 🧵 👇

[George Robinson @GeorgeARobinson]

New paper alert! Sex differences in #Tregs may drive #autoimmune susceptibility @TheLancetRheum
Supported by our study, considering sex and gender in #immunology research is fundamental
@Jury_Lab @UCL_RheumAYA @inespinedatorra Gary Butler @peijnuj @Pekiiii
https://t.co/dRRO5Uad8h

[Lupus S&M @Lupus_SM]

Interesting #work from the @McDonnellLab showing #evidence of overlap between #complement and #coagulation in #SLE patients: #Anti-FXa and #Anti-Thrombin #Antibodies can change complement activation in vitro
https://t.co/uKt6EIgy7z

[The McDonnell Lab @McDonnellLab]

Happy to share our latest paper in collaboration with @uclaps and @AnisurRahman60 on Anti-FXa and Anti-Thrombin Autoantibodies in SLE showing a new mechanism for C3 and C5 cleavage!

https://t.co/3XDmXOVVAH

[Prof Inés Pineda-Torra 🇪🇺🇪🇸🇺🇦 @inespinedatorra]

Yay!!!👏👏👏🎉🎉🎉

[The McDonnell Lab @McDonnellLab]

Calling all APS Patients! Help steer our research in the McDonnell lab for the next few years. Please click on the link and give us your opinions and thoughts! Thank you! #APS #PatientVoices #Research

https://t.co/VuzsA4yIvs

@APSFA @APSsupportUK @uclaps @StickyBloodOrg

[Savino Sciascia @SavinoSciascia]

Crosstalk between complement and vasculitis explained by @Roby13048499 #Autoimmunity2022 @autoimmunitymd #vasculitis

[Dr Gurdeep S Dulay @gurdeep_dulay]

@MassimoRadin @CerveraRicard Emerging area of interest 🤔

⬇️ complement (C3/C4) in *some* patients with catastrophic #APS

🔘Prob due to genetic variation
🔘Protective effect of ⬇️C5
🔘so…C5 inhibitor (Eculizumab) may have role in treatment

cc
@uclaps @APSFA @APSsupportUK

[Hannah Peckham @Pekiiii]

Amazing time at @CHelveticum in Zürich Sex and Gender in Immunity meeting! Fantastic talks from everyone 🤩🤠 and many thanks to @ChloePasin for the opportunity to share some of our work at the adolescent centre @UCL_RheumAYA ☺️👩‍🔬🔬👨‍🔬☺️

[The McDonnell Lab @McDonnellLab]

Happy to share this exhaustive review of chronic inflammatory placental disorders by the excellent @ecor89. Great work!
https://t.co/KFFC4xbHbx
#placenta #CHI #VUE #MPFD #Review #Inflammation

[UCL APS Research @uclaps]

@McDonnellLab @FrontImmunol @APSsupportUK @APSFA @StickyBloodOrg

[The McDonnell Lab @McDonnellLab]

Happy to share our new paper with @uclaps on PEGylated DI inhibiting #Thrombosis in a Chronic Mouse Model of #APS #AntiphospholipidSydrome https://t.co/CHt4ETaYb1
@FrontImmunol

[The McDonnell Lab @McDonnellLab]

@uclaps @FrontImmunol That means PEGylated DI has worked to reverse thrombosis in inhibition assays (IgG & IgA) in a functional coagulation assay (IgG) and in acute and chronic mouse models! #NovelTherapies #APS #FutureIsBright

[UCL APS Research @uclaps]

@pallett_lab Personal pipettes. That's when you know you've made it.