Here's a visualization comparing* sema and tirze for #weightloss in ppl with #obesity or #diabetes
My estimate of therapeutic efficacy goes like this, from least to most:
sema 1.0
sema 2.0
tirze 5 ( = sema 2.4)
tirze 10
tirze 15
SGLT2 inhibition in patients hospitalized for acute decompensated heart failure: rationale for and design of the EMPULSE trial - short trial (90days), with and without T2DM, HFpEF and HFrEF included, clever primary outcome composite to include KCCQ https://t.co/6ylJ3z0AWe
What has this wonderful beach to do with metformin? Here 4 old friends decided to review evidences on metformin benefits on heart, brain and kidneys, finally hypothesizing that an increase in the reviled lactate production/uptake may explain its effects. https://t.co/3l0LnPuSHi
Preview of 2021: Cardio-renal-metabolic medicine https://t.co/FvKBQKWc3m via @YouTube is out now. We discuss what we are looking out for in what should be an eventful year. Remember to hit the subscribe button. @drkevinfernando@AmarPut@drpatrickholmes@dr_amritlamba
@mostro15119736 1.rispondere ai fascisti con toni da fascisti è da fascisti https://t.co/slmzRLjhER storico accademico dovrebbe dare il buon esempio https://t.co/CP82XfTgGX Meloni è stata eletta democraticamente, anche se non riesco a farmene una ragione
An impressive STEP! Once-Weekly Semaglutide in Adults with Overweight or Obesity ⬇️14.9% weight at 68 weeks = 15.3kg (mean BMI 37.8)! 86% had > 5% reduction [50% had >15%]! https://t.co/gCW6mB3YqQ @NEJM@AmDiabetesAssn@EASOobesity@EASDnews@EASDelearning@UK_ASO
One in three adults in the US is prediabetic. Some will progress to severe diabetes, while some may not get full blown diabetes. This @NatureMedicine paper finds six sub-types of prediabetes.
https://t.co/95lxXfgSEf
The Circadian #2021resolutions anyone can use.
* 8 h in bed
* Wait for >1 h before first calorie.
* Eat within a consistent window of 8-10 h; no longer than 12 h.
* >30min outdoor activity under daylight.
* No food, no bright light for 2 h before bedtime.
REPEAT.
In T2DM, SGLT2i as first-line treatment associated with ⬇️ heart failure hospitalisation, acute coronary syndrome, and all-cause mortality vs metformin as first-line treatment
Database study
https://t.co/vS5RtBXmuW
Unfortunately #EASD2021 will be a virtual event again next year 😢
"EASD Board has unanimously decided to run the EASD Annual Meeting as an online event in 2021."
@drpratikc