Jay

I like writing, web design and short walks on the beach. Trying to heal from March 2020 #LongCovid #MCAS Creator:

[Hannah Davis @ahandvanish]

New study out from the amazing @MichaelPelusoMD et al!

They looked at both:

a) whether viral antigen persists after COVID infection (it does, in 25% of people!!)

b) which tests were more likely to pick this up

1/ #LongCovid

[Amy Proal, PhD @microbeminded2]

It’s official: A new Lancet Infectious Disease paper solidifies evidence of long-term viral persistence after #COVID-19.

Up to a quarter of people in the study harbored viral proteins indicative of persistent virus for up to 14 months after infection: https://t.co/2fLehSW9gq

[Danielle Beckman @DaniBeckman]

More evidence of direct #SARSCoV2 brain invasion points out that the neurological, cognitive, and psychiatric symptoms associated with COVID-19 might not only be driven by circulating inflammatory cytokines and indirect neuroinflammation.

@Gaudinlab just published a study examining human brain samples from individuals with COVID-19, cerebral organoids, and organotypic culture of human brain explants.
Their results are similar to what I also observed in the monkey brain:
The primary neural target of SARS-CoV-2 is mostly found to be neuronal, although other neural cell types have been reported to show some degree of permissivenes."

This is why SARS-CoV-2 will never be like the Flu. Show me an influenza strain that directly infects neurons in the primate brain.

[Kashif Pirzada, MD @KashPrime]

This is amazing, France is going to require clean air in classrooms, aiming at CO2 levels of 800 ppm. Other countries should quickly follow suit. Aside from limiting Covid, just the benefits of lowering common respiratory viruses makes this worth it alone, as any parent knows.

[Laura Miers @LauraMiers]

June 2022: “Kids were admitted…with a startling range of 7 respiratory viruses. They had adenovirus & rhinovirus, RSV & human metapneumovirus, influenza & parainfluenza, as well as Covid — which many specialists say is to blame for the unusual surges.”

(Two years later, it looks like Covid is changing the HOSTS.) https://t.co/gSxnWbAVpI

[Long Covid SOS @longcovidsos.bsky.social @LongCovidSOS]

📽️Fascinating treatment in Japan for inflammation of the epipharynx - claimed among other things to help restore function of the hypothalamus thus resetting the autonomic nervous system

Has helped with #LongCovid symptoms

Recommend watching to the end
https://t.co/6hKePckpc7

[Bateman Horne Center @BatemanHorne]

Exciting news! Our phase 2 clinical trial for Long COVID, featuring valacyclovir and celecoxib, is currently in progress, and we're thrilled to announce that we've already enrolled 50% of our target participants!

Learn more & get involved.
��️ Click here: https://t.co/L1rcD74VJj

[Billy Hanlon @bhanlon15]

'Long COVID a driver of unemployment'

'The main finding of our study is that reporting long COVID after SARS-CoV-2 infection is associated with increased odds of labour market inactivity and long-term absence compared with pre-infection'

https://t.co/mQPD3aLvRC

[Scientific American @sciam]

Research shows that even mild COVID-19 can lead to the equivalent of seven years of brain aging https://t.co/hstXJKCh95

[Dr Graham Lloyd-Jones @DrGrahamLJ]

I’ll say it again

Dear medical colleagues who write about acute #COVID

Stop calling the lung disease ‘pneumonia’

It is not!

It is a pulmonary vasculopathy, a disease of the lung blood vessels

Pneumonia causes airways inflammation

COVID is the opposite of pneumonia!

Thanks

[Sue [email protected] @inkblue01]

There's growing evidence that the virus is mutating in the body in distinct anatomical compartments. The sequencing of SARS-CoV-2 from the both lung samples doesn’t match the sequence found in the brain, suggesting evolution.🧠Daniel Chertow MD👇🧵

[Hiroshi Yasuda (保田浩志) @Yash25571056]

"The scientists found pieces of SARS-CoV-2, referred to as COVID antigens, lingering in the blood up to 14 months after infection and for more than two years in tissue samples from people who had COVID..
They detected portions of viral RNA for up to two years after infection, although there was no evidence that the person had become reinfected.
They found it in the connective tissue where immune cells are located, suggesting that the viral fragments were causing the immune system to attack.
In some of the samples, the researchers found that the virus could be active."

We have already been living with COVID.

'COVID-19 virus can stay in the body more than a year after infection, research finds'
https://t.co/EE2S39Jzom

[Billy Hanlon @bhanlon15]

POZ: 'First Tissue Bank May Help Solve Mystery of Long COVID Misery'

UCSF scientists, including long-time HIV researchers, believe persistent SARS-CoV-2 reservoirs play a role in protracted symptoms.

https://t.co/I2WUPHk4Ju

[Late Stage Society @LateStagePlanet]

"We observed Lewy bodies in brains of all rhesus macaques."

For me this is probably the most disturbing #Covid paper out there. This was after one infection. Imagine what happens if this turns out to be only 50% true.

https://t.co/fRFzqiCbYZ

[Sue [email protected] @inkblue01]

"Patients chronically infected with SARS-CoV-2 can develop genetically specific viral populations across distinct anatomical compartments."
https://t.co/a84FkOAPH3

[Prof. Akiko Iwasaki @VirusesImmunity]

Delighted to share our latest work on #longCOVID - sex differences in symptoms and immune signatures. Led by @SilvaJ_C @taka_takehiro @wood_jamie_1 et al. with @LeyingGuan & @PutrinoLab. We find a striking inverse correlation btw testosterone levels and symptom burden👇🏼 (1/)

https://t.co/XUGHcnVJKJ

[Hazie Thompson @haziethompson]

Big thanks to Chimére for letting me do my little part to help bring her amazing vision to life.
Check out https://t.co/Fe0ieL2d9L for more info and ways to support!

[Billy Hanlon @bhanlon15]

Nature, 2/9/24: 'Gut microbiota composition is altered in postural orthostatic tachycardia syndrome and post-acute COVID-19 syndrome'

https://t.co/DIjXfqEH7p

[Alberta Medical Association (AMA) @Albertadoctors]

🆘🚨THE URGENCY IS REAL
"Over 5000 patients will be without primary care."
1 doctor.
1 practice.
1 message.
Dr. Heidi Fell
Save Family and Rural Medicine with Budget 2024