I often meet with grad students and postdocs interested in industry. I tell them how important it is to contact people. Most jobs aren't posted, and most people are nice. However, students often push back, thinking networking is transactional and a bit icky 1/
Biopharma co’s pitching VCs – when talking about the commercial opportunity for your drug candidates, it’s wise to exercise some rigor and conservatism. This will build credibility with investors as well as help you elucidate some of the key commercial questions early. To...1/11
Glycobiology feels very undervalued in its therapeutic potential. As we 1) learn more about the role of glycans in disease and 2) develop better tools to read and write glycans, I think we're going to see a big increase in the clinical impact of glycobiology: (1/7)
The @nytimes typically has excellent reporting, but this article on non invasive prenatal testing is quite misleading and unnecessarily alarmist. https://t.co/z2cNKTVWst
private 🇩🇰 dermatology specialist Leo Pharma got their IL-13 approved in the US
LEO Pharma Announces FDA Approval of Adbry™ (tralokinumab) as the First and Only Treatment Specifically Targeting IL-13 for Adults With Moderate-to-Severe Atopic Dermatitis - https://t.co/XYzSXDAh5a
New Research: Milk From Women Diagnosed With COVID-19 Does Not Contain SARS-CoV-2 RNA but Has Persistent Levels of SARS-CoV-2-Specific IgA Antibodies: Background
Limited data are available regarding the balance of risks and benefits from… https://t.co/5BO7aNgWpL #immunology
New Research: Tracing Human IgE B Cell Antigen Receptor-Bearing Cells With a Monoclonal Anti-Human IgE Antibody That Specifically Recognizes Non-Receptor-Bound IgE: Up to 30% of the population suffers from immunoglobulin E (IgE)-mediated… https://t.co/GKrXtsmskK #immunology
Just published @NEJM
A striking 90% reduction in death for booster shots (vs not receiving the 3rd shot) among over 840,000 people, age 50 or older
https://t.co/W22vriA1Se
NEW: people worry when they hear "40% of hospitalisations are fully vaxxed", but this chart shows that's actually good news.
The more people you vaccinate, the higher their share of hospitalisations, but the *total* number in hospital is a fraction of what it would otherwise be
Here’s the key table from @PHE_uk new report on vaccine efficacy against hospitalisation with Delta variant:
After 1 dose
• Pfizer: 94% effective
• AstraZeneca: 71% effective
After 2 doses
• Pfizer: 96%
• AstraZeneca: 92%
Full preprint here: https://t.co/JQQjo0gSdg
9/If you are the National Advisory Committee on Immunization, then surely you can muster the resources to accompany your advice for “informed consent” with a tool that will enable that otherwise very complex informed consent process in the real world. It’s on you.
8/If you think your risk of contracting COVID is really low, here is a tool to help you to compare that risk with the risk of a vaccine complication: insert infographic decision aid comparing COVID vs VITT risk by: age, comorbidities, basic risk behaviours, community incidence.
7/There are always exceptions. If you live in a low risk neighbourhood, and/or are at extremely low risk (e.g. you never leave your house), it may be reasonable to wait for an mRNA vaccine, which doesn’t have this type of complication.
6/In fact, this complication is so rare that the average Canadian’s chances of dying in a car accident over 1 yr are about 10x higher than having this complication, and the average Canadian’s chances of dying of COVID since the start of the pandemic have been about 100x higher.