10y outcomes on S3 #TAVR vs SAVR in intermediate risk pts in P2A S3i is out #NYValves2025! @tnazifMD presented similar site reported ☠️ (~80% dead in 10y with mean age 80) and low reintervention (3 and 3.2%) between two groups among survivors. It gives us a good picture of the survival curves among these pts.
ACC 2025 LATE BREAKING CLINICAL TRIALS - One LINER SUMMARY 📸 AT A GLANCE ⭐️ What a phenomenal scientific meeting! Congratulations to all the presenters &research leaders for yet another fantastic year of innovation & research. 🫀❤️ 😊 #ACC2025 @ACCinT@ACCinTouch@uw_cvm@CardioNerds
Featured Clinical Research Summary coming soon! 🤩
First day at #ACC25, here are the results of 10 trials presented today. I counted 3 NEJM, 1 Lancet, and 1 JAMA.
WARRIOR: Intensive medical therapy did not reduce major CV events at five years in women with suspected INOCA.
STRIDE: Semaglutide improved walking distance, symptoms, and quality of life in PAD with diabetes.
API-CAT: Low-dose apixaban was noninferior to full-dose for preventing VTE recurrence in cancer patients.
RIVAWAR: Rivaroxaban was as effective and safe as warfarin for post-MI LV thrombus resolution at three months.
FARES-II: Four-factor PCC was superior to frozen plasma for bleeding control in cardiac surgery.
REVERSE-IT: Bentracimab reversed ticagrelor’s antiplatelet effects in urgent surgery or major bleeding.
HOST-BR: Three-month DAPT reduced adverse events without more bleeding vs. one-month in high-bleeding-risk patients post-stent.
SOUL: Oral semaglutide reduced MACE by 14% over four years with no safety concerns.
ADVANCE-HTN: Lorundrostat significantly lowered systolic BP at 12 weeks in uncontrolled hypertension.
DAPA-TAVI: Dapagliflozin reduced mortality and heart failure worsening post-TAVI vs. standard care.
Here’s my guide to navigate the #ACC25 trials, coming this weekend and featured in many journals with a (very) high impact factor.
1. WARRIOR = Intensive medical therapy in women with ANOCA/INOCA
2. STRIDE = Semaglutide in type 2 diabetes and peripheral artery disease
3. API-CAT = Reduced-dose versus full-dose apixaban in cancer with VTE
4. FARES-II = Four-factor prothrombin complex in cardiac surgery
5. REVERSE-IT = Bentracimab in uncontrolled bleeding or requiring urgent surgery or invasive procedures
6. RIVAWAR = Rivaroxaban versus warfarin in left ventricular thrombus after MI
7. SOUL = Oral semaglutide in type 2 diabetes with ASCVD and/or CKD
8. ADVANCE-HTN = Lorundrostat in uncontrolled hypertension
9. DapaTAVI = Dapagliflozin in transcatheter heart valve treatment
10. MIGHTy-Heart = Two strategies for improving transition to home after heart failure hospitalization
11. FRESH-UP = Liberal versus restrictive fluid intake in chronic heart failure in outpatient setting
12. FAIR-HF2 = Intravenous iron in heart failure with iron deficiency
13. PROTECT-TAVI = Embolic protection in TAVI
14. ALIGN-AR = Dedicated transcatheter aortic valve in aortic regurgitation
15. Evolut Low Risk = TAVI in low-risk
16. FLAVOUR II = Angiography-derived FFR versus IVUS in PCI
17. TRILUMINATE = Tricuspid transcatheter edge-to-edge repair in tricuspid regurgitation
18. FAME 3 = FFR-guided PCI versus CABG in multivessel disease
19. RACER = Out-of-hospital cardiac arrest during long-distance running events
20. Altshock-2 = Intra-aortic balloon pump in heart failure complicated by cardiogenic shock
21. ECLIPSE = Intravascular imaging to guide PCI of severely calcified lesions in PCI
22. HOST-BR = DAPT duration based on bleeding risk
We are ready to kick-off Module lll of the 2024 ACE Valve Academy! Join us for more cases and education with TAVI experts from across EMEA.
Delighted to collaborate with Liverpool Heart and Chest Hospital, one of the UK´s best hospitals, for this edition on 10-11 September.
I almost always use a figure of 8 to close 8F to 24F venous access sites. I haven’t had any major issues and I still send many patients home same day. I’ve been tempted to move to perclose but not sure the real benefit. Anyone using perclose routinely on venous closure? Tips/advice?
https://t.co/agEdPOBOZe
what I like most from 18th EBC consensus: keep things simple and limit number of stents. knowledge of anatomy is essential so please stop starting by default with DK Crush, which should be restricted to very few anatomical scenarios @EuroInterventio https://t.co/E2sbvwhOA5
This is one of the largest meta-analyses on the effects of exercise on cognitive performance.
Here are my top 4 evidence-based protocols from it to leverage exercise to maximize cognitive performance.
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I would add
- DO NOT READ your slides!it is very annoying as everyone has already read everything so we do not need to hear again % of events in groups.
- STOP making copy & paste of tables. the size is very small and none will read it.
@PCRonline#europcr
A quick recap of new randomized trials in the fields of coronary and valvular interventions you may have missed this year at #EuroPCR if you were only watching live cases or attending practical sessions.