damion99_hl🐉

decrypting | Deving | #Defi ◼️ storm-chaser ◼️ Never Rekt (After LUNA) • • 🔔 Lesson in there | part-time trencher ¬ sol '21

[damion99_hl🐉 @vic_bryson]

There are secret esoteric techniques hidden in the corners of the deep web which will teach you how to do things you've only dreamed of, the catch is that they only work once you've become the type of person who could have invented them without the PDF in the first place.

[MoneyRadar Crypto @MRadarCrypto]

🚨🇸🇻El Salvador vient de légaliser le hold-up fiscal le plus agressif du siècle. Et les paradis fiscaux traditionnels sont en train de mourir.

Le président Nayib Bukele a activé le décret 531 : il suffit désormais de passer seulement 90 jours par an sur place pour obtenir le statut de résident.

Les avantages pour la communauté crypto sont absolument délirants :

-0 % d'impôt sur le revenu d'origine étrangère.
-0 % de taxe sur les plus-values Bitcoin.
-0 % d'impôt sur la fortune ou les successions.

Pendant que l'Occident asphyxie ses entrepreneurs sous une bureaucratie confiscatoire, Bukele transforme un ancien pays ultra-dangereux en un hub sécurisé fiscal optimal et pour toute la famille, écoles internationnales, système de santé amélioré, plages, climat chaud .☀️

Le piège est pourtant immense. El Salvador n'hésitera pas à céder face au fisc de votre pays d'origine si vous ne coupez pas correctement vos attaches. Le paradis a un prix, et les administrations fiscales occidentales ne vous laisseront pas partir sans un combat féroce...

[damion99_hl🐉 @vic_bryson]

@base Based @base

[damion99_hl🐉 @vic_bryson]

@base

[damion99_hl🐉 @vic_bryson]

@base $base $virtuals

[Max @TALK_L3SS]

I remember when I was a kid in the 90s hanging out with a bunch of really smart activist punk types, people that had read every book about revolution etc. They said you'll know when society is about to collapse because everything will jut become more and more expensive day by day

[MP𖤐 @MagicalPep]

I still can’t believe Diego Maradona was literally handed cocaine to sniff right after scoring a goal. 😭

[Geopolitics & Empire @Geopolitics_Emp]

"Huxley got it. Which is why he took the view that the dystopia he wrote of in Brave New World (and warned of further in his slim nonfiction tract Brave New World Revisited) wouldn’t be based on people’s avoidance of pain but rather their love of pleasure.
Incentives.

Desires which, once they’ve been tasted, become insatiable.

Those who want control will supply satisfactions for them for free!" https://t.co/zfYACzIOvh

[VirtudMental @VirtudMental]

En la Antigua Grecia, se prohibía a los esclavos hacer ejercicio para que no se fortalecieran lo suficiente como para rebelarse.

A los gladiadores romanos se les alimentaba con cebada y frijoles para mantenerlos grandes, pero lentos, de modo que no pudieran conquistar a sus amos.

En el Imperio Otomano, se prohibía beber café para que los ciudadanos no se rebelaran.

A los esclavos espartanos se les dejaba deliberadamente con poca comida y se les sobrecargaba de trabajo para prevenir rebeliones.

En la Europa feudal, a los campesinos se les daba pan y avena, mientras que los nobles se daban banquetes de carne roja.

Controlar a una población comienza con la comida y el ejercicio.

¿Entiendes lo que está pasando hoy en día, verdad?

[UBERSOY @UBERSOY1]

By the 6th generation, your genetic contribution to a descendant is 1.56%. By the 10th, it's below 0.1%. By the 20th, it is dissolved into the collective pool. The obsession with individual lineage is meaningless at civilizational timescales.

[UnveiledChina @Unveiled_ChinaX]

Nearly half (47%) of China’s entire non-government workforce is now trapped in the gig economy, a staggering mathematical reality that redefines the country's economic crisis.

While the daily grind of this "flexible" workforce is clear, official data from the National Bureau of Statistics (NBS) and state-linked research exposes the true structural gravity of the situation. Out of China's roughly 730 million total employed citizens, only about 50 million secure stable, coveted public sector and government roles. This leaves a remaining private workforce of 680 million people left to navigate the open market.

When you overlay the China New Employment Forms Research Center's projection that the gig economy will swell to 320 million people this year, the math becomes undeniable. This is no longer just a temporary safety net for displaced workers. It means nearly half of China's entire independent labor force has been systematically locked into precarious survival mode.

With official data proving that almost half of China's private workforce is now confined to the gig economy, do you think this structural shift can permanently absorb the economic slowdown, or is it building a dangerous social and demographic time bomb?

#ChinaEconomy #GigEconomy #FlexibleEmployment #LaborMarket #EconomicCrisis #ChinaJobs

[Comet @cometwtf]

FOUR friends tricked FIFA's servers into making them $18 MILLION and thought they were doing nothing wrong.

> In 2013, a 23 year old named Anthony Clark from Whittier, California discovered that EA's FIFA servers had a bug

> He and three friends built a tool that tricked the servers into thinking thousands of matches had been played. None of them ever happened

> Every fake match rewarded them with FIFA coins, the in-game currency players normally earn by actually playing

> They sold those coins on black market sites to buyers in China and Europe, who resold them to real players desperate to build their Ultimate Team

> They registered a company called RANE Developments, opened a business bank account, filed taxes and treated the entire operation like a normal startup genuinely believing it was legal

> Over two years they generated between $15 and $18 MILLION in FIFA coins without ever touching a controller

> Ricky Miller bought a Lamborghini. Anthony Clark put nearly $3 MILLION into a single Bank of America account

> All four had houses, luxury cars and cash stacked across California

> On September 17, 2015 the FBI kicked in all four doors simultaneously and seized everything

> Anthony Clark was convicted of wire fraud in 2016

They filed taxes, they registered a company, they thought they were entrepreneurs but EA Sports had other plans.

[k4ylee🖤🎀 @Fw_k4ylee]

left wing drugs:
weed
LSD
xanax

right wing drugs:
meth
cocaine
zyns

We need centrist drugs for radical centrists.

[H @hmmmmmm1458]

난 게임을 즐겨하지 않는데 이런건 진짜 유익함

만원으로 데이터 센터의 복잡한 구조와 컴퓨터 인프라를 이해하는 스팀게임 : Data Center

빈 방에서 시작해서
랙 구매 → 서버 장착 → 모든 케이블을 직접 손으로 하나하나 연결해야함

실제 데이터 센터처럼 고객 트래픽을 처리하는 시뮬레이션 게임

출시 48시간 만에 180개가 넘는 리뷰가 달렸고, 플레이어들은 “최근 본 시뮬레이션 게임 중 가장 몰입감 있다”, “컴퓨팅 인프라를 이해하는 데 최고”라는 평가를 하고 있습니다.

[Raven @raven_brah]

Boomers when they see you peacefully fishing on a lake that is nowhere near their property line

[Eztainutlacatl @cbkwgl]

Around 2600 BC, Indus Valley created a mineral, ernstite for drilling carnelian and agate. Only recently people realized that it's not a natural mineral but it's made out of heating sandstone and laterite to 1100 degrees. You know how important is that for human technological evolution? There are only two other items in the whole of human history before Industrial Revolution which are near to it in hardness(7.5-8 on Moh's Scale) - Wootz Steel(again, Indian) and porcelain. Just think. For more than 4000 years, humans weren't able to match that technology. 4000 years!!

[vx-underground @vxunderground]

I don't know the whole lore, but nine crypto drainers and/or sim swappers have been apprehended in the UAE.

According to Threat Actors, cryptocurrency nerds (including ZachXBT), the people in the UAE are being tortured.

The full extent is currently unknown, however it's been reported the UAE government has broken their fingers, pulled their teeth out with pliers, and beating them in detention cells. They're still locked away.

These nine individuals have been in Dubai flexing expensive watches, partying with models, showing off expensive cars, etc. None are citizens of the UAE.

I don't know what they did to make the UAE so angry, but they're extremely angry. I also don't know if prisoners have the same rights in the UAE as you would countries like the UK or USA.

[Financelot @FinanceLancelot]

Fantastic explanation of the Yen carry trade and how the crisis unfolding in Japan will affect the entire world.

I've posted charts showing the parabolic Japanese yield curve and Yen-to-Dollar to see visually how this becomes a problem in 2026.

[George Ferman @Helios_Movement]

This is your reminder that some people with slow COMT consume 18000% of the RDA in methylated B vitamins and wonder why they have anxiety.

The catechol-O-methyltransferase enzyme is encoded by the COMT gene and its job is to break down catechols and turn them into forms that can be easily eliminated or recycled in the cells.

Catechols include:
-Dopamine
-Epinephrine
-Norepinephrine
-Certain estrogen metabolites like 2-hydroxyestradiol (catechol estrogens)
-Substances with a catechol structure by default, which also means certain drugs and natural compounds like quercetin.

Now, how does COMT break these down?

Well, as its name states, it’s a methyltransferase. This means that it transfers a methyl group from a donor molecule to its substrates, with the donor being S-adenosylmethionine (SAMe) (so COMT relies on methyl groups from SAMe) and the substrates being catechols.

The process looks like this: Catecholamine + SAMe + Mg²⁺ → Methylated Catecholamine + SAH.

*Once SAMe hands over the methyl group, it turns into S-adenosylhomocysteine (SAH) and magnesium binds to COMT’s active site to facilitate the methyl transfer.

Here are the forms that COMT methylates dopamine, epinephrine and norepinephrine into:
1. Dopamine becomes 3-methoxytyramine (3-MT).
2. Epinephrine becomes metanephrine.
3. Norepinephrine becomes normetanephrine.

Then, these are further metabolized by MAO in the case of 3-MT (it gets turned into homovanillic acid (HVA) and is excreted in urine) or vanillylmandelic acid (VMA) in the case of metanephrine and normetanephrine.

Aldehyde dehydrogenase (ALDH) also contributes to these after MAO.

What’s also a good idea to mention is that COMT operates in two forms:
1. S-COMT (a soluble version)
2. MB-COMT (a membrane-bound version)

The first one is found throughout the body and helps with general catecholamine metabolism and the second one is more active in the brain, mainly in the prefrontal cortex, with a higher affinity for dopamine and norepinephrine.

So as you might be able to tell, the COMT enzyme plays an essential role in maintaining neurotransmitter levels at the right amounts and thus impacts our attention spans, mood, working memory and reaction to stress.

Note 1: Alleles are the possible versions of a gene at a specific spot (locus) on a chromosome.

Example: At the rs4680 spot in the COMT gene, the alleles can be G (valine) or A (methionine).

Note 2: A genotype is the specific combination of genetic material—of alleles you have at a given gene locus (e.g., GG, GA, or AA for rs4680) or sometimes as the amino acid outcome.

Note 3: Homozygous = both alleles are the same (Val/Val (GG): Two G alleles at rs4680, coding for valine in COMT (Met/Met (AA): Two A alleles, coding for methionine)).

Note 4: Heterozygous = the alleles are different (Val/Met (GA): One G and one A allele, a mix of valine and methionine).

Note 5: Phenotype = genotype plus environment.

Now the main SNP we care for is: Val158Met polymorphism (rs4680) where a single nucleotide change that swaps valine (Val) for methionine (Met) in the enzyme.

In case you have it, you will either have:

Slow COMT (met/met) (catecholamines don't clear out fast which increases the risk for an overload and this even cancer (remember that's also responsible for catechol estrogens))

Fast COMT (val/val, G/G) (catecholamines clear out quickly (3-4 times faster than the slow version) which might leave you short on dopamine for example)

Note 1: We could also have G/A = Val/Met (intermediate).

Note 2: Other COMT SNPs are rs6269, rs4633 or rs4818 (*) that tweak how much COMT enzyme is produced(**) (the tips for these "overlap" with the ones for rs4680 but focus on fine-tuning based on expression levels).

(*) rs6269: G (higher expression) vs. A (lower expression), rs4633: C (higher expression) vs. T (lower expression), rs4818: C (higher expression) vs. G (lower expression).

(**)High COMT expression for example (G-C-C haplotype) means more enzyme = faster catecholamine clearance.

Low COMT expression (A-C-G haplotype) means less enzyme = slower clearance.
\
Now here are specific tips for fast and slow COMT.

Number 1: Fast
-Do not go vegan or vegetarian
-If you can tolerate dairy products such as cheese, it would be a good idea to incorporate one portion/day
-HIIT
-Low dose TMG
-Glycine
-Mucuna
-P5P (cofactor for tyrosine hydroxylase (dopamine synthesis)).
-Magnesium taurate
-Rhodiola

Number 2: Slow
-NAC
-Lithium orotate
-DIM
-Magnesium glycinate
-Whole food vitamin E
-Experiment to see if supporting methylation through low dose (100-200mg) SAMe supplementation or methylated B vitamins (mainly B12 and B9) work for you
-Avoid supplements that can deplete methyl donors, such as high doses of niacin
-Avoid dopaminergic supplements such as mucuna
-Avoid caffeine
-Manage your body weight very carefully.
-White button mushrooms
-Whole food vitamin E
-Avoid COMT inhibitors such as quercetin or luteolin

More: https://t.co/SobzY4skY7

[Sean Mike Kelly @seankelly25]

The Las Vegas Everyone Loved Is Officially Dead

[MERICA MEMED @Mericamemed]

Mr. Beast proved that they don't want institutions or a foundational system on which to build civilization. He dug simple wells in water starved areas. The locals then proceeded to blame him personally because he wasn't coming back to maintain them.