Built an app to show how Rentosertib actually works. 🧬✨
It recently showed an anti-aging effect in clinical trials. 👀
GPT-6 Astra again. The crazy part: ~40 minutes to build, plus an MD simulation 🤯
@Derya_tm@EvgenyKirilin, this really feels like a new level of structural analysis.
Rentosertib inhibits TNIK, a kinase and one of the molecular switches controlling signaling inside our cells. ⚙️ Kinase activity is also exactly the kind of property Insilico Medicine’s models are built to predict. 🤖🔬
#insilicoSOTAFM
What if all we really needed was explosive bodyweight training, plyometrics, and brutal consistency not lifting heavy-ass weights every session?
Prison gym bros be looking JACKED with nothing but push-ups, pull-ups, dips, squats, burpees, jumps and sprints😭
Built an insane model of the human cell in just 30 minutes 🤯
GPT-6 Astra is ridiculously powerful. Can’t wait to put it to the test on biological tasks.
@RimShayakhmetov@DeryaTR_ take a look!
Proud to have been part of this one. The method matters more than the headline here — you can measure geroprotection inside a normal disease trial, without waiting decades to notice by accident.
Mycoplasma gallisepticum is widely recognized as one of the smallest known free-living, self-replicating cells in the world. Here is its model generated by Astra.
All proteins shapes, sizes and abundances are real!
What a time to be alive!
Mycoplasma gallisepticum is widely recognized as one of the smallest known free-living, self-replicating cells in the world. Here is its model generated by Astra.
All proteins shapes, sizes and abundances are real!
What a time to be alive!
🧬 Rentosertib just turned back biological age in people.
⏱️ 6 aging clocks. 6 independent groups.
After 12 weeks, all 6 clocks read them 3 to 4 years younger.
🚀 The first AI-designed drug. The first clinical demonstration of 3–4 year biological age reversal.
The first experiment is done. 🔬 Now run your own with Insilico’s SOTA models.
#InsilicoSOTAFM