I am so excited to share our new paper in @Nature: the first programmable, site-specific integration of a large DNA payload into T cells in vivo.
A single IV injection results in therapeutic levels of TRAC-targeted CAR T cells in multiple models.
https://t.co/t3pyjHyGWS
a 🧵
What if we could engineer T cells in the body, making CAR T vs cancer, autoimmune diseases, and other applications far more practical, much less expensive?
A step forward today via genome editing T cells
https://t.co/FjgQA8NUlu
https://t.co/XXk43WL1ac
We are recruiting! If you are passionate about technology development, protein engineering, computational design, directed evolution, chemical biology - please reach out!
(The setting is pretty nice too…)
Thrilled to share our new review article from our lab titled 'Rewriting the epigenome: CRISPR tools for biological discovery and therapeutics.' led by @cotero926. Free download for the next 50 days! #epigenetics#crispr#synbio https://t.co/z6rWgk6gpC
If you work with T cells, chances are high that you've used CRISPR/Cas9 to knockout genes. But did you know that CRISPR tools can not only engineer the genome, but that you can also directly engineer epigenetic regulation or process RNA, completely without DNA-damage?
Great science yesterday afternoon full with exciting talks of the ESRs from @enacti2ng! Guys, you rock science! Thanks Marie Curie EU Training Networks #MSCA#ETN! Looking forward to more talks today! Really a pity not to meet in person 🥲
Today we want to share an interview from one of our partners in the consortium: Christoph Trenzinger from STRATEC Cons. Christoph talks about his research and future plans as well as his experience as a PhD student in industry.
https://t.co/0o3FNyniKB