Congrats to Salma Merchant for Cell Stem Cell paper: effects of fatty acid oxidation in hematopoietic stem cells are context dependent. FAO not necessary in young HSCs, but becomes necessary during aging, & deleterious when upregulated by a high fat diet.
https://t.co/rV4xxQ5ynM
AI can be used to make convincing looking fake data.
There is no way we can distinguish real from fake anymore.
It is safe to assume that genAI has already resulted in many fake papers. Scientific publishing is not prepared for this.
See here how brain tumor cells dynamically recruit neurons during cancer progression with rabies-based retrograde tracing! #CancerNeuroscience#FluorescenceFriday
The phrase ‘metastasis accounts for 90% of cancer deaths’ is one of the most widely used in cancer research, yet it is overly simplistic, imprecise, and it is difficult to find any primary analysis supporting the statement. | → https://t.co/kiv5NQsUZL ← | 🧵(1/5)
Super Happy to share that our study is now online.
We report that Glucose-driven histone lactylation promotes the immunosuppressive activity of monocyte-derived macrophages in glioblastoma.
@MoffittNews@TheWistar
https://t.co/sReh7bJNPV
Excited to share our new work identifying new routes through which the brain waste is being removed and immune cells may come inside the brain. Congrats to Leon and all coauthors. Thread below! 👇
Great new work from @EishuHirata in @Dev_Cell ! Astrocytes favour brain metastasis by promoting mGluR1 expression in cancer cells and stabilising EGFR. Interesting therapeutic implications & cool brain TME mimetic culture method too. https://t.co/RIeV3GNxpt
Excited to announce our lab's recent publication to @CellReports comparing different microglia cre lines. Congratulations to recent graduate @AliciaMBedolla and other authors. https://t.co/gD0PdMKzzq
We are exited to share our discovery of excitatory synapses between neurons and tumor cells in brain metastases of breast cancer & melanoma. The groundbreaking study co-led by @VarunVenkatara2 and me, with Thomas Kuner & @WinklerLab: https://t.co/50UTK4M33G #CancerNeuroscience
Starting the new year with an updated version of our database of funding opportunities for EARLY-CAREER RESEARCHERS/FACULTY.
For each of the 496 entries, we provide description, link, deadline, amount, eligibility criteria
Download for free here: https://t.co/RGXGrdpAjN
Our self-propelled CAR T cells expressing synthetic “velocity” receptors infiltrate pancreatic tumors like its butter (bottom). Control CAR T cells can’t (top).
Game over.
Works in any solid tumor; can transform any CAR T of your choice into a Ferrari.
https://t.co/bfAty2bCtu
It's all about the base!
Check out our new review in @trendscancer :
https://t.co/BxqNk0K3ew
With @LMonteran@YaelZait we discuss the fascinating roles, similarities and unique tasks of organ-specific stromal cells- CAFs, osteoblasts and astrocytes in their metastatic niches.