https://t.co/0PvIVS3HwK
Opinion:
* keep indications for metastases-directed local therapy (MDT) and the biology of OMD conceptually apart
* serial clinical imaging is key
* declare failure of MDT only at progression to polymetastatic disease if unamenable to re-MDT
NRG LU002 closed after phase II and will not go on to phase III. Seemingly same situation and same reason as NRG BR002: PFS again was primary endpoint, and PFS still is not a suitable primary endpoint for trials comparing MDT vs systemic only therapy. (https://t.co/T7Wg707NPt)
I would like to thank all the patients, investigators, institutions, protocol team members, @NRGonc, @NCICancerTrials, and many others who helped with NRG LU002. We made incredible history in successfully randomizing to the largest OMD NSCLC trial to date evaluating local therapy
"On behalf of the European radiation oncology community and our patients, ESTRO urges a return to responsible communication presenting scientific facts in a balanced manner with headlines that inform rather than alarm."
Overall this is an advance for the management of patients with rectal cancer but patients need to be carefully selected, closely monitored, and informed of the trade offs between the toxicity profiles of various treatment options. @ASCO@ESTRO_RT@Mat_Guc
The American Society for Radiation Oncology (ASTRO) Gastrointestinal Cancers Resource Panel issued the following statement regarding the PROSPECT clinical trial for patients with rectal cancer: https://t.co/rLSb19y0OW
The abysmal state of global research funding on key domains such as surgery, radiotherapy and health services. Combined less than 4%. How have research funding organisations managed to get their strategic priorities so wrong? @cspramesh https://t.co/QahAfMjsK1
Double-blinded phase III RCT: RT vs sham-RT for painful Morbus Ledderhose (n=84 pts)
Sig. benefit of RT
👉 1a mean pain score 2.5 vs 3.6 (p=0.03)
👉 1a pain relief 74% vs 56% (p=0.002)
👉 improved QoL & walking speed
👉 mild RT tox
👏 first RCT
#radonc
https://t.co/hPUoXBlfmd
Honored to present @ESTRO_RT the results of the @EORTC E2-RADIatE #oligocare international cohort analysis including 1468 patients treated with #SBRT in #oligomet. See you in Vienna. https://t.co/CI70ve8ii3
@MedUni_Wien@JCO_ASCO Gyn Unit CCC Vienna/Rad.Onc.
MR-IGABT: New emerging standard in treatment for cure of locally advanced cervical cancer.
N=1318
LC: 95% SCC, 86%
OS > 80% at 5y