Azzeddine Tahiat, @BogunovicLab et al. show that complement inhibition in #CHAPLE disease restores serum immunoglobulin levels, re-establishes a normal B cell profile, & enables effective humoral protection & optimal vaccine responses. https://t.co/m9Kfj6GC6c
#IEIs
Excited to share our discovery of a new programmable RNA-guided DNA-targeting system hiding inside bacteriophages that predates CRISPR.
We call it VIPR (Viral Interference Programmable Repeat), and it uses an entirely new logic to find its targets.
Thread + link below.
This is a thorough, critical, and superb Review of a complex and controversial human B cell subset, the famous "ABC" -- a must-read !👇
Human CD21loT-bet+ B cells: Not as easy as “ABC”! https://t.co/tITEtFlKC5
amazon's internal A.I. coding assistant decided the engineers' existing code was inadequate so the bot deleted it to start from scratch
that resulted in taking down a part of AWS for 13 hours and was not the first time it had happened
incredible
https://t.co/K5dW15ioVH
@19keys_@majtoure An equally common disposition nowadays is stubborn disbelief to any narrative or framework no matter how well established or obvious. These same “skeptics” funnily enough find it easy to believe any patchwork circumstantial and correlative argument if it isn’t “mainstream.”
Excited to announce the submission of the second major study from my postdoctoral work with @HuangLabDuke. A big shout-out to @jessemaurica and other talented collaborators @WilliamGalbavy@borshuen! https://t.co/gyxPpkWjIL
Careful dissection of the specification & laminar deployment of cortical glutamatergic projection neuron types in mice, with noteworthy deviations from a simple inside-out pattern, by @DhananjayHuilg1@HuangLabDuke@jessemaurica@WilliamGalbavy@borshuen
https://t.co/NtyfqPgjSy
Signal boost for this wonderful work from @DhananjayHuilg1 & team (myself included!) Using innovative genetic strategies to answer fundamental questions in neurogenesis & brain organization on a structural, cell type, & even circuit basis! A well deserved congrats to DJ!!