This is worth watching. Like everyone in my age group, I’m sad about his death. Be warned: it’s a hard video to watch if you know someone dying of cancer. But he says some beautiful things. I slightly knew James van der Beek when we were kids; we took piano lessons back to back and had mutual friends. It brings me back to that time. RIP, far too soon.
James Van Der Beek was one of the biggest stars when I was young.
Every girl I liked, liked Dawson's Creek.
He was in Varsity Blues among other movies.
I was sad to hear of his passing, but this is probably the WISEST thing I've ever heard from a guy.
He tried finding value & defining himself in various ways...... the only one that mattered in the end was CHRIST FOLLOWER & child of God.
RIP James.
Enjoy the pearly gates. 🙏❤️
We've spent 50 years trying to kill cancer cells. What if the answer was never to kill them but to remind them who they are?
Cancer cells aren't foreign invaders. They're your own cells that lost their identity. They stopped differentiating, stopped maturing, and started growing without limits. Cancer doesn't create anything new. It hijacks normal biology.
Researchers at KAIST in South Korea identified three master regulators, MYB, HDAC2, and FOXA2, keeping colon cancer cells locked in a malignant state. When they silenced all three? The cancer cells differentiated back into normal, healthy tissue. MYC and WNT pathways shut down. In mice, tumors shrank significantly.
No chemo. No radiation. Just reprogramming.
Here's what most people will miss: HDAC2 is a histone deacetylase. It compacts DNA and silences tumor suppressor genes. We already use HDAC inhibitors in our protocols. This isn't new to us. But it's powerful validation.
Cancer and aging are the same problem. Cells that no longer serve the body but learned to hijack the immune system to survive. The answer isn't bigger bombs. It's restoration.
Still preclinical. But the direction is exactly right. Kudos to the @kaistpr team. 👏
ESPN sources: former Colts QB and current St. Michael Catholic High School coach Philip Rivers is interviewing today for the Buffalo Bills head coaching job.
Major cheat code for life: The ability to sit across from someone and have a real conversation. Eye contact. Good questions. Listening without waiting to reply. In a world consumed by screens, it’s amazing how rare this is and how much trust it creates when you can do it well.
A 4.8 magnitude earthquake hit west of Manhattan and has been felt throughout New York.
My team is assessing impacts and any damage that may have occurred, and we will update the public throughout the day.