My life's goal isn't to be rich.
It's to work 3-4 hours per day, help thousands of people, have plenty of time for exploring hobbies, spend time outside, cook with my wife, exercise whenever I want, and avoid pointless meetings.
That's all I care about.
The most valuable skill in the world:
Decision-making.
I studied how Naval and Elon Musk make decisions.
Here's how you make decisions like world-class entrepreneurs:
Laparoscopic intra-corporeal ileal loop diversion( ileal conduit) followed by laparoscopic simple cystectomy (Michigan group technique).
Total operative time: ~5 hrs.
Special thanks to @Alialsulihem@malmuaiqel
And to our resident @khalafalshmrani
عملية تحوير المسار البولي بالكامل عن طريق المنظار الجراحي ، واستئصال المثانه بالكامل لأسباب حميدة.
Prostatic Artery Embolization vs TURP:
"All outcomes, including IPSS, QOL, peak flow, and postvoid residual volume (PVR), were equivalent at 12 and 24 months. TURP --> higher rates of bladder catheterization and hospitalization. Major complications were encountered only in the TURP group."
https://t.co/fnjDNBENmD
#iRad
🔬 BREAKTHROUGH ALERT: Revolutionary HoLEP (Holmium Laser Enucleation of the Prostate) en bloc technique showing unprecedented success rates! The new approach reduces the operation time by 30% while improving patient outcomes. This minimally invasive approach improves benign prostatic hyperplasia treatment. The future of urology is here! #HoLEP #LaserSurgery #BPH #MinimallyInvasive #UrologyInnovation #PatientCare #ICUA
New data shows ultra-low-dose nivolumab (20mg) outperforms standard chemo in advanced cancers. It extended life, cut severe side effects by nearly 20%, and protected QoL.
Less can be more.
@ASCO@JCO_ASCO@OncoAlert
Really enjoyed this consensus conference tackling the gray areas in GU oncology 👥🧠
Bringing together experienced GU colleagues, acknowledging where evidence is limited, and laying out thoughtful, real-world options sparked a truly rich discussion 💬✨
A great read and practical resource for anyone caring for GU patients 📚👇https://t.co/PHfWCICrlz
#GUonc #BladderCancer #KidneyCancer
2026 @AmericanCancer Statistics are out. #prostatecancer is now #1 in incidence for all US ppl. Mortality numbers also up though ASR is slightly down; mortality still >2x for Black men.
New USPSTF guidelines expected this year… Get screened!!
https://t.co/7KktgaNbCi
ctDNA gives a good indicator of MRD post surgery in MIBC & is predictive of response to atezo. It is also prognostic in most MIBC settings. Less is known about utDNA. In SUNRISE4 the utDNA results are novel & show utDNA clearance, which may correlate with pCR. Integrated utDNA and ctDNA analysis will help guide treatment IMO @AndreaNecchi
Localised prostate cancer just changed. Again.
ESMO 2026 brings clarity on who to observe, who to escalate, and which trials actually matter 👇
🧠 Diagnosis
MRI before biopsy is standard
High-resolution US is a valid alternative (RCT n=678)
🧭 Low risk
Active surveillance is safe
ProtecT 15-yr data shows similar survival vs RP/RT
☢️ Radiotherapy
Shorter is better
CHHiP ➜ moderate hypofractionation
HYPO-RT-PC ➜ ultra-hypofractionation
PACE-B ➜ SBRT works in selected IR disease
📈 High risk
RT + long-term ADT saves lives
SPCG-7 | NCIC/MRC
Dose escalation improves OS (GETUG-AFU 18)
🚨 Very high-risk / cN1
RT + ADT + abiraterone is the new benchmark
STAMPEDE delivers MFS + OS benefit
🔁 Biochemical recurrence
Avoid routine adjuvant RT
Early salvage RT preferred
RADICALS-RT | RAVES | GETUG-AFU 17
High-risk BCR? Intensify
EMBARK supports enzalutamide + ADT
🧠 Bottom line
Risk-adapted care > overtreatment
Imaging-driven decisions
Escalate only when trials prove benefit
📖 Full paper in comment ⬇️
#OncoTwitter #MedTwitter #ProstateCancer #GUOncology
@OncoAlert@myesmo@esmo_open@asco@OncBrothers
What’s the future of muscle invasive bladder cancer #SimposioSOGUG25
Pathological CR rates of 57% for EVP points towards cystectomy being delayed until maximum EVP effectiveness. Also fewer patients will have cystectomy. Studies are needed to ensure this approach is safe.
While discussing ctDNA in bladder Ca #SimposioSOGUG25 more data from IM011 becomes available. Negative patients are at low risk while +ves benefit from atezo. These data further support using ctDNA rather than other approaches to select patients for adjuvant IO in UC #SUO2025
An important read for all enucleators… great work from Prof. Mario Sofer and cols. They propose a very interesting new concept, a new mechanism that contributes to explain temporary stress incontinence after AEEP, the radial forces exerted by the scope during enucleation