Yihan Chen

RA #SCUT | MS @XJTLU | Bioinformatics | Enzyme-ML | Web3 | 中/粤/EN | Views are my own. | Previous #JilinU

[Yihan Chen @YikhamChan]

@ze_notme 美如画

[Graham Heimberg @gheimberg]

Ever analyze a scRNAseq dataset and wonder if a specific cell state has been seen before? And if so, where in the human body? Under what conditions? Well, now you can use our lightning fast SCimilarity search and foundational model for that! ⚡️🔎🧬 https://t.co/t8L1xFOffd (1/11)

[Rafael Irizarry @rafalab]

Clustering algorithms report clusters even when none exist. In single-cell RNA-Seq pipelines, novel cell types are often identified by clustering algorithms. Expanding on Kimes et al.'s work, we introduce significance analysis for single-cell RNA-Seq data: https://t.co/ut1kPjKVCM

[Yihan Chen @YikhamChan]

@JunYin29422166 一直没感觉生化材坑在哪，科研也可以走，工作也可以找。非要说的话只有环境专业确实是性价比低了一些。

[Steven Ge @StevenXGe]

#Bioinformatics colleagues! Take a quick look at the top 75 Bioconductor packages.
I discovered some I should've known about but didn't.
The ones I clicked are tied to pathway analysis.

[Xiaole Shirley Liu @XShirleyLiu]

Congratulations to @TheodorisLab on the recent study, demonstrating the power of AI learning from big data to make meaningful predictions on limited data.

[Yihan Chen @YikhamChan]

@hi_caicai @oulvhai 搬这个东西去Apple Store还真不容易😂，好在买了acplus等过��年再去换了。

[Yihan Chen @YikhamChan]

@hi_caicai @oulvhai 会黏黏的，目前看来无解。

[Frank Glorius @GloriusFrank]

From small molecules (here: imidazolium salts) to bioactive RNA degraders - promising story, just published in Nature.🧬😀⚗️
International collaboration of @disney_lab & Herbert Waldmann & @GloriusGroup & John Cleveland
@UFScripps @mpimoph @WWU_Muenster
https://t.co/afPQKP2KbW

[antisense. @razoralign]

scGHOST: Identifying single-cell 3D genome subcompartments https://t.co/vVwJqXnLnu

[Yihan Chen @YikhamChan]

@initiumnews Respect or not does not depend on the language used, but rather on the attitude and content of the speech. Do not confuse the key point.

[Zhiqiang Sha (@zhiqiangsha.bsky.social) @sha_zhiqiang]

The complete sequence of a human Y chromosome
https://t.co/xGDzcZs6Yz

[Yihan Chen @YikhamChan]

That’s why I have always doubted whether ergonomic chairs really live up to their claimed effectiveness ���🤷.

[BioDecoded @BioDecoded]

A relay velocity model infers cell-dependent RNA velocity | Nature Biotechnology
https://t.co/HsuXeVXjgG

#DeepLearning

[Prof. Nikolai Slavov @slavov_n]

How accurate are 'gene regulatory networks' inferred from scRNA-seq data?

This comprehensive analysis in @naturemethods concludes:
1. The areas under the precision-recall curve are moderate
2. Methods not using pseudotime-ordered cells are more accurate

[Yihan Chen @YikhamChan]

@harshameghadri Maybe have them build a simple biological database on a topic that interests them or that they have learned in school, using a tool like MySQL or MongoDB?

[Yihan Chen @YikhamChan]

@mranti 代驾也需要人为输入目的地嘛，有工具帮忙节省时间总归是好的，就可以有更多精力探究新事物，未来值得期待。

[Yihan Chen @YikhamChan]

@Maxwell_SCU ICP+神经网络加速器，效率拉满。

[Andy Russell @AndyRusss]

Single-cell or spatial?

Our new technology - Slide-tags - allows both in the same experiment, enabling true single-cell multi-modal spatial genomics

➡️ https://t.co/i1m5T4bEme

[Giorgia Tosoni @georgietos]

☕️ Fresh out of the press in @NeuroCellPress!!

Happy to share our manuscript “Mapping human adult hippocampal neurogenesis with single-cell transcriptomics: reconciling controversy or fueling the debate?” @LabSalta @NIN_knaw

https://t.co/EsJk9mojDw

🧵1/n