Yunus Edgü

Used to be interested in Historical Linguistics&History. PhD, Peer Review 31'leyenler gelmesin lutfen. Likes and Retweets ARE Endorsements.

[Yunus Edgü @ynsedgu]

@burcayerus @Alp_bugdayci1 @tsoncu1 Çalışan sayısı azalırken emekli sayısının artışına dair somut bir hesap öneriniz nedir?

[Yunus Edgü @ynsedgu]

@burcayerus @Alp_bugdayci1 @tsoncu1 Tamam, ama bu da indirgemici bir yaklaşım farkındasınız umarım. Sermaye emek antagonizmasına indirince de kuşaklar arası maliyet farkını görmezden geliyorsunuz. Sermayeye yüklenebilecek şeylerin de bi sınırları, iktisadi yansımaları var

[Yunus Edgü @ynsedgu]

@tsoncu1 @burcayerus @Alp_bugdayci1 1) gerekli nominal para yaratılabiliyor mu? 2) yarattığında çalışanların yaşam standartları ve diğer kamusal ihtiyaçlar hiç etkilenmiyor mu? Devlet para yaratabilir de mal, hizmet ve işgücü yaratamaz. Çalışan nüfus azalırken emekli sayısı artıyorsa bunun maliyetini kim ödüyor?

[Yunus Edgü @ynsedgu]

@burcayerus @Alp_bugdayci1 @tsoncu1 Tamam, peki gelecekteki emeklilerin hayatından doğrudan-dolaylı yoldan çalmak da kötü insan olmaya çıkıyor aynı mantıkta. Günümüzdeki emekliler sürdürsün diye kime yükleniyor bu?

[Charles Brenner, PhD @CharlesMBrenner]

sirtuins are not conserved longevity genes

https://t.co/CRSjopHatU

[Crémieux @cremieuxrecueil]

The FDA has fallen into an amusing trap.

GLP-1RAs don't cause this. But, some of the conditions it treats do.

Result? 'Warning!'

[Jesse Morse, M.D. @DrJesseMorse]

Some of these new Retatrutide numbers are crazy impressive from the TRIUMPH-1 study:

70% reduction in knee pain score (‼️)
60% reduction in sleep apnea episodes
8-12 mm Hg drop in systolic BP
34-41% drop in triglycerides
15-20% drop in LDL
58-64% drop in inflammation 🤯
88-96% return to normal blood sugar 👏🏼
Massive positive impact on quality of life

Retatrutide is a CHEAT CODE.

It’s like 5 peptides in 1.

…and there’s more ⬇️

[Robert Barton @howbrainsevolve]

From language and memory to music, dance and narrative, humans display a remarkable capacity to understand and create complex sequences. How did such capacities evolve? Consider joining us in Bristol next April 5-6th to help us find out https://t.co/2BDkE3EOum

[Jesse Morse, M.D. @DrJesseMorse]

🚨 All the hard work paid off!!!

The following 6 peptides will be able to be legally prescribed in the United States on Friday, October 30th:

BPC-157
TB-500
MOTS-c
Epithalon
Semax
KPV

The future of medicine is here!!!

@StackHealth @peptavo @peptidemedicine

[Paul Graham @paulg]

We're about to enter a period where not reading or writing becomes as ubiquitous as smoking once was. We can hope people will eventually realize this is bad for them, as they did with smoking. But this is far from certain; the cost may not be as obvious.

[Jesse Morse, M.D. @DrJesseMorse]

Now that genetic testing is much cheaper and easier to access than it used to be, this is one of the alleles I’ll be monitoring in my longevity patients.

It’s called ‘CYP1A2’ and correlates with slower processing of caffeine.

If you feel like caffeine hits you really hard and you can’t ‘handle’ caffeine, this is likely the reason why.

It’s fascinating because the data for coffee, predominantly caffeinated, is really strong for longevity and overall health.

Yet this data seems to show a pretty significant increase in risk of heart attacks.

Genetics wins again.

[Mustafa Türkan @mstfturkan]

Noir’da mümkün yeni açılımlara dair makalem Quarterly Review of Film and Video’da. https://t.co/31dsUKGzA1

[Jesse Morse, M.D. @DrJesseMorse]

Jalen Hurts, why these blood clots could be career-ending:

In short:

He will always be at increased risk for blood clots, for the following risk factors:

He has multiple blood clots in his lungs currently
Frequent travel due to occupation
Recurrent hits secondary to occupation
History of COVID virus (massive clot risk)
History of COVID vaccine (confirmed)

Players can’t play a contact sport while on blood thinners.

Only way to prevent development of future blood clots knowing the above risks?

Being placed on blood thinners indefinitely (likely the rest of his life).

IMO I don’t think a medical staff would ever clear him to play football again.

Chris Bosh 2.0

[FischerKing @FischerKing64]

There are so many podcasts now on so many topics.

Just read a fucking book. You will be more knowledgeable.

[Jesse Morse, M.D. @DrJesseMorse]

Huge News regarding Retatrutide‼️

“FDA has now ruled AGAIN that retatrutide is a drug, not a biologic, saying its 39 alpha amino acids do not meet the threshold for a protein or an ‘analogous product.’”

Eli Lilly is trying to make Retatrutide the exception to the rule.

Retatrutide is 39 amino acids, where 40 amino acids qualifies for the drug to be considered a biologic.

39 is not 40.

Eli Lilly tried to get cute and add 2 small side chains to try to get it over the 40 amino acid threshold but it’s not working.

This decision will have MASSIVE implications as it pertains to price, (compounding) availability as well as patent length.

The fight continues…

[Mustafa Türkan @mstfturkan]

Yeni makale yayında.

Makalenin merkezinde Şevket Süreyya Aydemir’in birincilik kazanan İş Birliği adlı senaryosu yer alıyor. Filme çekilemeyen bu proje, köy eğitimi, kadın emeği, kooperatifçilik, tefecilik karşıtı siyaset ve “milli” sinema arayışını aynı hikaye içinde buluşturuyordu. Biz de kooperatifçi söylemin dergilerden, cemiyetlerden ve iktisadi tartışmalardan çıkıp bir senaryo yarışmasının kamusal alanına nasıl taşındığını ve İş Birliği’nin okurlar ile yarışmanın jürisi nezdinde neden karşılık bulduğunu tartışıyoruz.

[dizzee @diz__zee]

"openai just proved that Riemann zeta is zero-free in the half-plane ℜ(s) > 7/8"

"incredible this changes everything"

"do you know what ℜ(s) is?"

"no, do you?"

"no."

[Simon Grimm @Simon__Grimm]

When I stilled worked on biosecurity, I first learned about Debug, a Google project to reduce mosquito populations.

Results from their Singapore pilot are now out.

They crushed mosquito populations, reducing dengue infections by 70% in the process:

[htw @heniek_htw]

Melatonin (5mg) worsens glucose tolerance & blunts first-phase insulin response by 40% – but ONLY in MTNR1B gene risk carriers (30-40% of people). Non-carriers unaffected. Key mechanisms: suppressed β-cell responsivity & disrupted insulin feedback.

[Charles Brenner, PhD @CharlesMBrenner]

small open label trial supported NR in human mito dz

however, the idea that this is mediated by SIRT1 is not supported by data

sirt1 KO mice have higher O2 consumption than wt & SIRT1 oe lowers mito proteins in muscle

SIRT1 literature is a mess

https://t.co/rz58fvIBSD