Dr. Zeynep Hülya Gümüş 🕊️

Associate Prof of Genetics and Genomics @IcahnInstitute & @SinaiImmunol & @TischCancer in NYC. Genetics, cancer, data sci & data viz

[Dr. Zeynep Hülya Gümüş 🕊️ @ZeynepHG]

Our study is out in @AjHematology: Distinct characteristics of lymphoid and myeloid clonal hematopoiesis in World Trade Center first responders #WTC @IcahnMountSinai @IcahnInstitute @TischCancer @SinaiImmunol @AIHealthMtSinai @stonybrooku @EsaiMyvizhi https://t.co/LcHv3LEt9Z

[National Cancer Institute @theNCI]

Researchers at NCI uncovered how liver cells decide whether fat is stored safely or becomes harmful—a key step toward understanding fatty liver disease and cancer. Fundamental discovery, multidisciplinary collaboration, and prevention-focused science are how we move cancer research forward. Learn more: https://t.co/RhAj8fq7lw

[Nature Methods @naturemethods]

Spatialproteomics: a Python-based toolbox for end-to-end analysis of highly multiplexed imaging data.

https://t.co/ZCg1ov15X7

[Dr. Zeynep Hülya Gümüş 🕊️ @ZeynepHG]

@lpachter I recall folks would use C++ as one of the foreign languages and it would be accepted, though.

[Monica Guzman @DrMonicaGuzman]

Proud to share our new piece in Blood Global Hematology, written with wonderful colleagues: @RobertaDemiche3 @castro_mollo @XimeJordan

"Hispanic/Latino" was built for policy, not biology. In leukemia, treating it as one group hides real diversity in ancestry, access & disease.

Rethinking Hispanic/Latino as an ethnic category in leukemia research https://t.co/dfvB2sOkPZ

[Dr. Zeynep Hülya Gümüş 🕊️ @ZeynepHG]

@NurBozbey1 @ilyassahinMD Merhaba Almanya'daki Hallwang kliniginde ABD'den getirtiyorlar; detaylarini onlarla iletisim kurarak ogrenebilirsiniz. https://t.co/Pf0gEbJiax

[Jay Shendure @JShendure]

Thrilled to post thread re: new single-cell lineage of mouse embryo reconstructed w/ DNA Typewriter. One animal, zygote to late organogenesis (E13.5). Tree has 1,340,794 transcriptionally profiled, annotated tips (cells), 1,142,588 dated internal nodes, rooted at zygote
1/n

[PBS News @NewsHour]

The State Department said ​it takes "full responsibility" for "hastily" altering and then presenting a map of Africa at a global AIDS conference that mislabeled every single country it highlighted.

An analysis by Reuters found a watermark in the map image that suggests it was made with OpenAI.

[Dr. Zeynep Hülya Gümüş 🕊️ @ZeynepHG]

Sometimes I will just let my AI deal with your AI instead of commenting that you are AI.

[Dr. Zeynep Hülya Gümüş 🕊️ @ZeynepHG]

@anshulkundaje Imagine all the new cancer treatments we could have developed with those billions and billions and billions....

[Ogün Adebali @compGenomics]

New paper!

How do hundreds of GPCRs maintain the same activation mechanism while evolving to recognize completely different signaling partners?

We developed an evolutionary framework that separates residues responsible for shared GPCR functions from those driving specialization

[Özgür Demirtaş @ProfDemirtas]

Sayın Aile ve Sosyal Hizmetler Bakanlığı,

Doğru olup olmadığını bilmiyorum. Kendisini de tanımıyorum. Ancak üstümde kalmaması için yazıyorum. Bana şu şekilde bir email gelmiş. Eğer doğru ise ve yardımcı olunabilirse çok sevinirim.

Başvuru No: #9274821 / 09.06.2026

Adı soyadı da: Şükran Kozak imiş.

@tcailesosyal

[Science Magazine @ScienceMagazine]

Researchers in Science report the development of a general-purpose biomedical AI agent that can help automate biomedical research workflows.

The authors say their results point “toward a future in which AI agents work alongside human researchers to accelerate biomedical discovery from basic research to translation.”

Learn more: https://t.co/74K6dI5iNt

[Alexandr Rakitko @AlexRakitko]

🧬Machine learning prediction of hypertension integrating polygenic risk scores in 175,704 inner Eurasian individuals from Genotek biobank🧡

Today our paper in Frontiers in Cardiovascular Medicine was published. We analyzed three PRS for blood pressure traits. The strongest effect was observed for the diastolic blood pressure PRS, with an OR of 6.7 for the top decile compared with the bottom decile

We also showed significant associations across different ethnic groups, including Russians, Mordvins, Ashkenazi Jews, Buryats, Yakuts, Armenians and populations of the North Caucasus.

The best-performing model was a Dense Neural Network with ROC-AUC = 0.82. The model integrated questionnaire-based risk factors, including age, sex, BMI, smoking, alcohol consumption, education, work type, physical activity and daily steps, together with three polygenic risk scores.

Overall, we showed that a combined model based on questionnaire data and three PRS achieves good predictive performance and transfers across different ethnic groups of inner Eurasia.

This work grew out of the master’s thesis of our student Vera Tsvetkova.

https://t.co/kyMohNGZFO

#PRS #Hypertension #MachineLearning #AncestryComposition

[Ronan Farrow @RonanFarrow]

Studies now present a striking picture of what happens when private equity firms acquire hospitals and nursing homes: predictable increases in harm and deaths. One landmark study shows: patient deaths up about 11% after such acquisitions.

[Marinka Zitnik @marinkazitnik]

Introducing ATHENA: an AI agent for treatment reasoning across all FDA approved drugs since 1939, by stellar @GaoShanghua

Paper: https://t.co/Du5sKHGKKD
Code: https://t.co/xdA1RTiSEJ
Project: https://t.co/2WrXDaZvDk

Every treatment decision means weighing disease context, comorbidities, drug interactions, contraindications, and evidence that keeps changing. That is an iterative reasoning problem. You have to figure out what evidence to go find before you can even start forming a conclusion.

Most LLMs answer from what is stored in their weights. Give agents tools and they often still do not use them well. Having access to a biomedical database does not automatically mean a model knows when to query it, what to ask, or how to weigh what comes back.

[Dr. Zeynep Hülya Gümüş 🕊️ @ZeynepHG]

@marinkazitnik @GaoShanghua @ayushnoori @CurtGinder @BenGlicksberg @RanBalicer @HarvardDBMI @KempnerInst @biohub @IcahnMountSinai @ClalitHealth @BrighamWomens wow. amazing!

[Inside Precision Medicine @Inside_PM]

Strong Public Support for Embryonic Genome Editing to Eliminate Severe Conditions, European Survey Shows

Over half of European survey respondents said they support #genomeediting in human embryos for the purpose of eliminating #severediseases
@PET_BioNews
https://t.co/7FDMiiY07J

[Prof. Nikolai Slavov @slavov_n]

Paying peer reviewers led to faster first editorial decisions — an average of 5.5 working days, down from nearly 38 for unpaid reviews.

The review quality, as judged by handling editors on the basis of helpfulness in making an editorial decision, went up.

1/

[Brendon Stiles @BrendonStilesMD]

Proud to share our latest work from @MontefioreNYC @EinsteinMed examining molecular testing in early-stage lung adeno. Comprehensive NGS revealed important differences in EGFR & KRAS subtypes in our diverse patient population, reinforcing why equitable testing and trials matter.