Zsofia Torok

Postdoctoral Scholar @UCSF-Ingraham lab. Studying estrogen regulation of hypothalamic non-neuronal and neuronal cells in different reproductive states.

[Zsofia Torok @ZsofiaTorok8]

I am excited to share my first-author pre-print in songbirds, where we explore mechanisms of brain circuit restoration at the behavioral, neuronal, and transcriptomic level over time - a collaboration with @alfairhall, @lpachter and @neuroluebbert

https://t.co/5FpXVS8uPP

[Archana Venkataraman @moolakaari]

Pretty stoked to share my postdoc work, now out in Science! 🎉
We show how estrogen ingeniously co-opts communication between gut epithelial cells to modulate pain.
https://t.co/xLTxGUfxTl

🧵⬇️ THREAD (1/11)

[Archana Venkataraman @moolakaari]

Thrilled to share our preprint -
A Cellular Basis for Heightened Gut Sensitivity in Females
https://t.co/4bcwvhkCAD

Why is GI pain more common in women?
Blame it on estrogen! It ramps up the cross-talk between L-cells and EC cells — making the gut more sensitive to pain signals.

[Holly Ingraham @hollyingrahamSF]

A fabulous team effort by Dr. J, @moolakaari, @sahmriAU, @ericfigueroaPhD (@SF_IRACDA ).
Might help explain why the low #LowFODMOP diet works in #IBS, #Gut.
Pretty exciting - made possible by taxpayers and funding from @NIH and @NIDDKgov.

[VarunWadia @WadiaVarun]

1/10 Very excited to announce that my thesis project is now a preprint! We present the first detailed study of mental imagery in human ventral temporal cortex, bringing together the interests of @doristsao and @UeliRutishauser. https://t.co/LBukzKqMOA

[Holly Ingraham @hollyingrahamSF]

A thread acknowledging the many contributions of the @UCSF @UCDavisHealth team for our study, out online at https://t.co/WPXWRTzjPU

1/7—We identify a new hormone, CCN3, produced in the hypothalamus to build bones and offset bone loss during lactation - a 5-year journey. One cover idea 👇.

[Holly Ingraham @hollyingrahamSF]

Scientists Discover a New Hormone that Can Build Strong Bones | UC San Francisco

Thank you ⁦@LauraKurtzman⁩ for a great summary of team effort with ⁦@dr_ambrosi⁩ https://t.co/jQS25Hphu3

[Zsofia Torok @ZsofiaTorok8]

I am thrilled to share our work showcasing the remarkable recovery of a complex learned behavior in a predominantly unsupervised manner! This achievement is the product of a fantastic collaboration with @alfairhall and her exceptionally talented trainees.

[Nature Neuroscience @NatureNeuro]

Unsupervised restoration of a complex learned behavior, song production, after large-scale neuronal perturbation causing severe song degradation in zebra finches

https://t.co/XVoqiTztNL

[Holly Ingraham @hollyingrahamSF]

A hunt, a surprise, and then clarity - Congrats to the team! Love 😍 it.

Brain-Derived CCN3 Is An Osteoanabolic Hormone That Sustains Bone in Lactating Females https://t.co/xCJIlDz2tZ

[Zsofia Torok @ZsofiaTorok8]

@nadsurya_ Thank you :)

[Zsofia Torok @ZsofiaTorok8]

@SumnerLN Thank you!

[Zsofia Torok @ZsofiaTorok8]

@NiaSanchezV Thank you!

[Zsofia Torok @ZsofiaTorok8]

@sarah_wandelt Thank you!!

[Zsofia Torok @ZsofiaTorok8]

Our experiments reveal that the adult brain can overcome extended periods of E/I imbalance. The deployment of mechanisms typically employed during juvenile learning suggests that circuit plasticity may persist throughout adulthood, awaiting reactivation for circuit restoration.

[Zsofia Torok @ZsofiaTorok8]

I am excited to share my first-author pre-print in songbirds, where we explore mechanisms of brain circuit restoration at the behavioral, neuronal, and transcriptomic level over time - a collaboration with @alfairhall, @lpachter and @neuroluebbert

https://t.co/5FpXVS8uPP

[Zsofia Torok @ZsofiaTorok8]

Next, we set out to measure the cellular and transcriptomic changes underlying song recovery. Single-cell RNA sequencing of HVC during the height of circuit restoration (25 days) revealed elevated levels of microglia and MHC I (not seen in virus-injected control).

[Sarah Wandelt @sarah_wandelt]

Super excited to share a preprint! At @Caltech, we build the first closed-loop brain-machine (#BMI) interface that is able to decode internal speech 💭. Check it out here: https://t.co/8bNDtGA6w2