The Cuervo Lab

A large bunch of scientists studying Chaperone Mediated Autophagy at Albert Einstein College of Medicine @einsteinmed *tweets and views are our own*

[The Cuervo Lab @AMCuervoLab]

1. We’re excited to share our latest paper, “Decline of chaperone-mediated autophagy (CMA) in aging impairs macrophage clearance of senescent cells” published
in @NatureAging led by @Beccasereda is now out! https://t.co/jRh81qso1R

[The Cuervo Lab @AMCuervoLab]

🗞️🚨 Chaperone-mediated autophagy curbs senescence

Check out the News and Views written by Shweta S. Dipali and @MattYousefzadeh about our most recent article. Thank you so much!

https://t.co/BpikTnaKn1

[The Cuervo Lab @AMCuervoLab]

Marta and Nader from our lab and Saba from @EAriasLab also presented wonderful posters 🎉✅

[The Cuervo Lab @AMCuervoLab]

Great science at the Glenn Symposium of Aging at @YaleWestCampus last Friday. Two great talks by Floralba and Kiya.

[The Cuervo Lab @AMCuervoLab]

Ana Maria will be speaking at the upcoming Autophagy in Health and Disease: From Mechanisms to Therapeutics conference, Feb 8-11, Banff, Canada

The scholarship + short talk abstract application deadline has been extended, do not hesitate to apply by October 28! #KSAutophagy27

[Keystone Symposia @KeystoneSymp]

⏳ Deadline extended to 10/28!

Protein degradation meet autophagy 🏔️
Scholarship + short talk abstract applications are open for #KSProximity27 + #KSAutophagy27, joint meetings in Banff, Feb 8–11, 2027.

Links to submit in the first comment!

[SEFAGIA (Sociedad Española de Autofagia) @SEFAGIA_]

#MeetingAlert Registration is now open for the SEFAGIA 2027 Congress, which will take place in Valencia-Alfara del Patriarca, from 3 to 5 February 2027.
Register here:
https://t.co/svyaXmeb13
We look forward to seeing you in Valencia!

[Diario Nutrición @diarionutri]

Alberto Díaz, Ana María Cuervo, Lourdes Herrera y Marta Garrido analizan en The Conversation si el ayuno intermitente 16:8 mantiene sus beneficios metabólicos al incorporar días de descanso
@DiazRuizAlberto @unicomplutense @IMIBIC @IMDEANutricion 
https://t.co/ihuRYPjCmt

[TimePie (focus on anti-aging science) @TimePieChina]

🎉TimePie Longevity Forum is featured in @NatureAging!

Appreciation to all the experts who contributed to the conversations shaping the future of longevity.
@KejunYing @AMCuervoLab @prof_horvath @gladyshev_lab @susanna_rosi @Vinz_Sorrentino, et al.
https://t.co/TDhGhIkdPm

[The Cuervo Lab @AMCuervoLab]

Lots of Cuervitos in Spain at the Hallmarks of Aging conference🥰

[Agingdoc🩺Dr David Barzilai🔔MD PhD MS MBA DipABLM @agingdoc1]

Decline of chaperone-mediated autophagy in aging impairs macrophage clearance of senescent cells

https://t.co/9UXSvhko3v

[The Science of Parkinson's @ScienceofPD]

A new review on chaperone-mediated autophagy in physiological homeostasis, disease & ageing has been publisehed; #Parkinsons gets a couple of mentions, but a useful overview of the biology & potential "gerotherapeutic" targets
https://t.co/qX02jPaTnu

[The Cuervo Lab @AMCuervoLab]

Check out our @EinsteinMed article as well! https://t.co/hV3LrjJldU

[The Cuervo Lab @AMCuervoLab]

1. We’re excited to share our latest paper, “Decline of chaperone-mediated autophagy (CMA) in aging impairs macrophage clearance of senescent cells” published
in @NatureAging led by @Beccasereda is now out! https://t.co/jRh81qso1R

[Aging Science News @AgingBiology]

Decline of chaperone-mediated autophagy in aging impairs macrophage clearance of senescent cells
https://t.co/9FUxUtDbJ4

[The Cuervo Lab @AMCuervoLab]

And congratulations to Susmita on her new review: https://t.co/r6Xa51vA4E !!

[Nature Reviews Molecular Cell Biology @NatRevMCB]

New Online! Chaperone-mediated autophagy in physiological homeostasis, disease and ageing dlvr.​it/TVnGnM

[The Cuervo Lab @AMCuervoLab]

10. Our findings identify CMA decline as a driver of senescent cell persistence and highlight CMA upregulation as a promising strategy to promote senescence resolution in aged organisms.

Thank you to all our collaborators and to our funding. We hope you enjoy our study!

[The Cuervo Lab @AMCuervoLab]

1. We’re excited to share our latest paper, “Decline of chaperone-mediated autophagy (CMA) in aging impairs macrophage clearance of senescent cells” published
in @NatureAging led by @Beccasereda is now out! https://t.co/jRh81qso1R

[The Cuervo Lab @AMCuervoLab]

9. In a bleomycin model, early CMA activation reduced lung fibrosis, senescence and inflammatory markers, and reshaped the immune response. Timing mattered: early treatment was more effective than delayed treatment.