Aina Mª Mas Calafell

Chromatin, epigenetics, and non-coding RNA

[Aina Mª Mas Calafell @AinaMMas]

Can distinct repressive histone PTMs substitute for one another?
We found that H3K9me3 and H3K36me3 can only partially compensate for loss of H3K27me3
https://t.co/Kf0thCbd0Z
@NatureComms @helin_kristian @LinHedehus

Our results support the concept of a combinatorial histone code

[Cima Universidad de Navarra @CIMA_unav]

📢 Progress from Cima: researchers develop ELATUS, a tool that detects long non-coding RNAs (lncRNAs), key in diseases such as cancer.

🔬 We detected the lncRNA AL121895.1, essential in breast cancer proliferation.

🔗 More details 👇 https://t.co/ffiJndgWFH

[Raimondi Ivan @raimondi_ivan]

🧬 We’re excited to introduce D&D-seq, a single-cell technology that maps DNA:Protein interactions through molecular footprinting.. Check it out here: https://t.co/mfsDO3kKa0 #Genomics #Epigenetics

[Kike Goñi @kike411]

Thrilled to announce that ELATUS is out in @NatureComms!
ELATUS uncovers functional lncRNAs in scRNA-seq missed due to poor annotation, such as AL121895.1, involved in breast cancer, providing insights into lncRNA biology. @MaiteHuarteLab @mikelhernaez

https://t.co/7RSt30bMq9

[Dciencia @dcienciablog]

Queremos contaros que La Fundación para el conocimiento Madri+d @madrimasd ha otorgado a @dcienciablog uno de sus premios de Ciencia en Español.

¡Muchas gracias por el reconocimiento!

Gracias a todos los científicos que habéis colaborado con nosotros y a nuestros lectores.

[Universidad de Navarra @unav]

Europa financia con 1,5 millones la investigación de Guillem Ripoll, profesor de @EconomUnav.
Ha recibido la beca 'Starting Grant' del @ERC_Research para analizar y prevenir el comportamiento iliberal en la administración pública.
#ERCStG
👉 https://t.co/SXMirXrJHX

[Maite Huarte @MaiteHuarteLab]

🚨 Paper Alert! 🚨
Does RNA regulation impact the p53 pathway and DNA damage response? We reveal distinct m6A-dependent and independent functions of the YTHDC1 protein.
Proud of the work by @BlazquezElvira @CIMA_unav, collaboration with @raimondi_ivan @nygenome
🔗 Read here 👇

[The ICR @ICR_London]

Do you want to know how we're using #AI to fight cancer?

Join us in the pub at the ICR's @pintofscience to hear our researchers talking about their work.

📅15 May
📍The Prince Albert Battersea SW11 4PF
🗣️@stephensammut & @boragurel

Book now: https://t.co/WiauV5w9h8 #Pint24

[Raimondi Ivan @raimondi_ivan]

Thrilled to finally share this work! @MaiteHuarteLab and I delve into the interplay between RNA regulation and DNA damage finding that "YTHDC1 m6A-dependent and m6A-independent functions converge to preserve DNA damage response"! https://t.co/VVwFrfTShL

[Aina Mª Mas Calafell @AinaMMas]

A must read!!!
Congratulations @kike411

[Kike Goñi @kike411]

Are all gene types equally targeted in scRNA-seq??
No! The essential and cell-type specific lncRNAs are largely overlooked by standard pipelines.

Here, we present ELATUS, a workflow tailored to lncRNA in scRNA-seq @MaiteHuarteLab @mikelhernaez

👇https://t.co/MkbYOoZIlx

[Luisa Statello @LuisaStatello]

Happy to share our latest paper in @NatureComms ! #lncRNA lncREST and its role in #replicativestress. Take home: lncREST associates to the stressed replication forks to recruit replication proteins to sites of DNA replication! @MaiteHuarteLab
https://t.co/AEK3XGT1L1
A 🧵:

[Maite Huarte @MaiteHuarteLab]

📢 Paper alert! Can a chromatin-associated lncRNA impact replication stress? Dive into the details of how lncREST localizes at stressed replication forks and enhances the assembly of fork signaling factors. Work led by ⭐️@LuisaStatello
https://t.co/aruDDI4KeU

[Aina Mª Mas Calafell @AinaMMas]

@dcienciablog @CIMA_unav @NatureComms https://t.co/kHAQI4wIFS

[Dciencia @dcienciablog]

Científicos españoles han descubierto que el ARN que se está “fabricando” es capaz de regular la replicación del ADN. La Dra. @AinaMMas, primera autora del trabajo nos cuenta el novedoso descubrimiento. @CIMA_unav @NatureComms

[Maite Huarte @MaiteHuarteLab]

Paper alert ‼️ 🚨
What is the role of RNA in the initiation of DNA replication? We have answers to this long standing question. Yes, RNA has a lot to say in how and where origins are activated. Check out our paper by amazing first author
@AinaMMas
https://t.co/2VqLrVKSig

[Vivien Marx🐘📬⛅️ @metricausa]

Sharing pizza is usually easy. Sharing data can be easy but it's often a bit less so. For my latest story, I chatted with some people all about this: To share is to be a scientist https://t.co/K72pe942D6

[Cima Universidad de Navarra @CIMA_unav]

¡Comenzamos el Genomics Day!!!
Una jornada para celebrar el 70 aniversario del #descubrimiento de la doble hélice 🧬 y 20anivesario de la finalización del #ProyectoGenomaHumano.
Más de 70 #investigadores reunidos para aprender las bases y nuevas aplicaciones de la #genómica

[Dciencia @dcienciablog]

La expresión de unos ARN largos no codificantes (lncRNAs) predice la supervivencia y prognosis de los pacientes de leucemia mieloide aguda pediátrica. Os lo explica la Dra. @AinaMMas del @CIMA_unav.

https://t.co/BkbnkARO1r

Adaptado de https://t.co/0tz7tNHUVj @ASCO

[Aina Mª Mas Calafell @AinaMMas]

Understanding the pathway:
Long Noncoding #RNA Signatures as Cancer Biomarkers

@MaiteHuarteLab @JCO_ASCO @CIMA_unav

https://t.co/D9lxsdYJ1P

[Irene Mota @IreneMota]

📢📢A novel role for microRNA in controlling sex determination!!

Check out our new pre-print!
https://t.co/4u0ThVs9Ix