🙄 what a novel concept that something as complex as healthcare decisions has many interests and incentives affecting decision making. That said, I think the overwhelming majority of MDs make decisions at the patient care level patient centered.
The dynamics of why things are done (or not done) in the healthcare system are shockingly complex and involve far more than medical matters
Do listen...below is the tip of the iceberg
If only we had recordings of conversations before LAAO
I’m neither a Christian nor a conservative. But, I have a deep respect for Ben Sasse and Ross Douthat and greatly appreciate their touching conversation. Thank you.
This morning, I asked President Trump if he’s okay with the Iranians charging a toll for all ships that go through the Strait of Hormuz, he told me there may be a Joint US-Iran venture to charge tolls:
“We’re thinking of doing it as a joint venture. It’s a way of securing it — also securing it from lots of other people.”
“It’s a beautiful thing”
Are we so far gone as a society that we will dismiss genocidal threats as either bluster from a conman or ravings from a madman? Deep into 25th amendment territory.
This is exactly why we’re in the mess we’re in. Trump’s capricious, consequence free erratic and non-strategic whims as official US policy. We have 3 more years of this…
Trump has insulted and tariffed his European allies, persuaded Denmark to prepare for a US invasion and, by pressuring Ukraine and not Russia, encouraged Putin to keep fighting. All of which he has forgotten.
https://t.co/GhDO27FyxK
@drjohnm Which is exactly my point. It’s why I’m super skeptical about the mortality “benefit” of LAAO vs warfarin give the number of ICH that occurred in the warfarin arm. Just as I am skeptical of the increased number of CVD in LAAO as a real signal in CL-AF. Worthwhile to be skeptical
For some reason, the post on CVD in LAAO trial included Protect/Prevail and P17, but truncated the Champion-AF results which show 36 in the LAAO arm and 38 in the DOAC arm (2.7%). Using an adjudicated mortality is grist for another post...
Some additional thoughts on CLOSURE-AF and CHAMPION-AF.
1. An interesting aspect of CLOSURE-AF is that the main driver of not meeting NI was NOT a difference in stroke/SE between LAAO and BMC (2.9% vs 2.8%), but an increase in major bleeding with LAAO and CV/unexplained death.
However, the 4% vs 0.4% incidence of major periprocedural bleeds is an intriguing finding and driving the failure to prove NI. Definitional? Technique differences in fem venous access to explain this? The routine use of ultrasound or micropuncture needles?