One in six species on Earth experienced extraordinarily high temperatures across more than 25% of their range in 2024--the hottest year on record. For most, this was the second year of extreme heat, likely compounding risks. In PNAS: https://t.co/KprLvA8QkT
The endoplasmic reticulum donates lipids through a tunnel-like protein to help lysosomes expand.
Learn more in a new #SciencePerspective: https://t.co/ifoNkP9oAG
'DNA-Programmable Protein Degradation: Dynamic Control of Proteolysis-Targeting Chimera Activity via DNA Hybridization and Strand Displacement' from JACS Au is an open access #ACSEditorsChoice.
📖 Read the article: https://t.co/R9qpi9jSPI
@UniofOxford@ucl@U_Tabuk
An alternative receptor enhances AAV transduction in vivo, offering the potential to reduce dose-related toxicities while maintaining efficacy in AAV-mediated gene therapy. https://t.co/rsXqUVRu6o #NBThighlight
A new ultrasound-guided #3Dprinting technique could make it possible to fabricate medical implants in vivo and deliver tailored therapies to tissues deep inside the body—all without invasive surgery, researchers report in Science.
📄: https://t.co/Z4SKxLOwmZ
#SciencePerspective: https://t.co/TScrVl6u9d
A study in @NatMentHealth explores the relationship between the genetic risk for schizophrenia and retinal thickness, demonstrating that neuroinflammatory pathways are linked to retinal thinning, with C-reactive protein partially mediating this effect. https://t.co/bk92B5A8GV
'Light-Controlled Adhesive Hydrogels for On-Demand Adhesion' from Chem & Bio Engineering is an open access #ACSEditorsChoice.
📖 Read the article: https://t.co/u8dfPOonRH
1/ THREAD: Where do mRNA vaccines go after injection?
Lipid nanoparticles (LNPs) are the workhorses of mRNA vaccines, but how do they move through the body?
New PET-CT imaging in rhesus macaques gives us answers. 🧵👇
What do we know about a #GPCR signaling pathway in rare forms of #melanoma? How can this help shed light on the balance between tumor growth and suppression?
Learn more in a new @SciSignal Review: https://t.co/5U0eV3Fk2k
There's an excellent commentary in Science as well
https://t.co/CoaSnv2iul
This work has clearly positive implications for live fluorescence and bioluminescence imaging of whole mice. Can't wait to see how it will change biological imaging in the future!
Congrats to my friend and colleague Guosong Hong for his stunning and original discovery, published today in Science, on clearing tissues *in living animals* with a common food dye!
The dye is tartrazine, used in Doritos!
https://t.co/fqVivyH0kI
I came across that @twan_lammers paper by chance. I am glad I did. Excellent work "Polymeric Microbubble Shell Engineering: Microporosity as a Key Factor to Enhance Ultrasound Imaging and Drug Delivery Performance" @AdvancedAms Here it is https://t.co/4dkMumeSa7
Watch how metals are 3D printed with sub-10 µm resolution! 🔬
Scientists @Westlake_Uni have developed an embedded-writing embedded-sintering process to create complex freeform geometries for custom microelectronics and metamaterials.
Find out more: https://t.co/IAF6r5vnyC