Alvin Chandra

[NEJM @NEJM]

Why has the United States handled this pandemic so badly? The Editors note that although we came into this crisis with enormous advantages, our current political leaders have demonstrated that they are dangerously incompetent.

[Alvin Chandra @AlvinChandraMD]

@pmyhre @AHAMeetings @Oslounivsykehus @DLBHATTMD Fantastic. Congrats Peder!

[Alvin Chandra @AlvinChandraMD]

Proud to share our subanalysis from TOPCAT study regarding depression in patients with HFpEF #JACCHF #HFpEF #depression.

https://t.co/px4eMFJhe1

[Alvin Chandra @AlvinChandraMD]

Fantastic work by @singh_kavisha which showcased the role of simulation in assessment of cardiology fellow performance in TTE scanning that's especially relevant in the COVID-19 era. @UTSWCardfellow
https://t.co/RwR5syzKAp

[Kavisha Singh @singh_kavisha]

The cholesterol story is never simple. Our work on multi ethnic cohorts from the US/Europe to see how HDL particles a/w vascular events and how that compares to HDL-C with @dranandrohatgi @AlvinChandraMD @DrPJoshi @dramitkhera @utswheart & others. https://t.co/5LivUWo8VV

[NEJM @NEJM]

Special Report: RAAS Inhibitors in Patients with Covid-19. #COVID19 #SARSCoV2

[Alvin Chandra @AlvinChandraMD]

So proud to share this @JAMACardio article written by my friend and colleague Dr. Riccardo Inciardi who's at the front line fighting #COVID19 in Italy. Also featured @nytimes. Thank you for sharing your valuable experience!

https://t.co/brqIdHhD4W

https://t.co/KmEuaNHErw

[Muthu Vaduganathan @mvaduganathan]

Striking data in @ESC_Journals #EJHF by @PeterMoliner: How do pts with HFrEF die? The answer appears to be changing if asked in 2001 vs 2018. Reflects treatment successes & new challenges!

Our accompanying editorial @RBPatelMD #AnjuNohria @JavedButler1

https://t.co/DFBGbBNLIE

[Javier Torres @JTLLERGO]

📍Health-Related Quality of Life in HFpEF: PARAGON-HF Trial (compared with PARADIGM trial)
📌 HRQL was largely worse in women and was similar in HFpEF and HFrEF
@JACCJournals @secardiologia @SACardiologia
https://t.co/ED3HzBrnFf

[ambarish @ambarish4786]

Congrats @mvaduganathan @Hirji1987 for leading this study and thanks to all the coauthors for their help and contribution @AqamarMD @bajaj_nav @AnkurGuptaMD @CardioOncology @JavedButler1 @AlvinChandraMD Bonnie Ky, Mark Haykowsky, @vgzmd, anju nohria @UTSWNews @UTSWCardfellow

[Peder L. Myhre MD, PhD @pmyhre]

Long-awaited #PROVEHF did not disappoint 🙌🏻:

-Rapid (<2w) and large reduction in NT-proBNP (at lowest #entresto dose)

-Sign reverse remodelling (LVEF +9% and LVMi -16 g/m2)

-Consistent in RASi-naive; low NP and non-target dose

CONGRATULATIONS @JJheart_doc @scottdsolomon

[Alvin Chandra @AlvinChandraMD]

Potential intriguing implications from the "neutral" #PARAGON_HF trial. Patients with lower LVEF may have benefits similar to #PARADIGM_HF #ESCCongress

[Alvin Chandra @AlvinChandraMD]

Rockstars in cardiology @escardio 2019 @scottdsolomon #PARAGON_HF #DAPA_HF #ESCcongress

[Christopher O'Connor @coconnormd]

Dapagliflozin home run for patients!

[Peder L. Myhre MD, PhD @pmyhre]

#PARAGONHF p=0.058 for primary endpoint: HR 0.87 (0.75-1.01)

👁Super interesting sex differences: HR 0.73 (0.59-0.90) in 👩🏻‍🦳 and 1.03 (0.85-1.25) in👨🏻‍🦳

👁Signal of better treatment effect with lower EF

Let the debate begin!
https://t.co/quU5zviG0q

@Novartis @scottdsolomon

[Alvin Chandra @AlvinChandraMD]

A paper we published a year ago closely related to our recent JACC HF #QOL in #HFpEF paper. @scottdsolomon

[JAMA Cardiology @JAMACardio]

In this post hoc secondary analysis of the PARADIGM-HF trial, sacubitril/valsartan improved limitations in physical + social activities that are common in patients with heart failure, including sexual activities #Entresto #NeprilysinInhibitor #HeartFailure https://t.co/KJ54IDKJe5

[Alvin Chandra @AlvinChandraMD]

It's like I'm rounding again with @MarkDrazner in the halls of old St. Paul Hospital. Thank you. @UTSWCardfellow

[Mark Drazner @MarkDrazner]

MY APPROACH to the Clinical Evaluation of Patients With Heart Failure https://t.co/lXAnWtvsGz via @practiceupdate.
Hope you find this useful!
@UTSWNews @utswheart @MKIttlesonMD @JTThibs @JLGrodin @HFSA @DrMarthaGulati @dramitkhera @UTSWInternalMed @UTSWCardfellow

[Alvin Chandra @AlvinChandraMD]

Thanks @mvaduganathan for sharing this! Proud to see our work with @scottdsolomon published

[Muthu Vaduganathan @mvaduganathan]

Largest assessment of #QOL across EF spectrum now pub @JACCJournals #JACCHF by @AlvinChandraMD & @scottdsolomon

Pooled data @PARAGONHF & #PARADIGMHF (n=11,622)

QOL worse in HFpEF compared w/ HFrEF, related to gender imbalance, ⬆️ signs/sx, & obesity

https://t.co/PBWm3X0Zjs

[Alvin Chandra @AlvinChandraMD]

Happy to share our findings published at #JACC from the #DallasHeartStudy regarding the association of temporal changes in body fat distribution and #hypertension

[JACC Journals @JACCJournals]

New #JACC paper examines the association of temporal changes in body fat distribution with #hypertension in a multi-ethnic cohort. https://t.co/PbFDAGN6dm