Amanda Murray

@PennBioeng @MJMitchell_Lab PhD student | @NSF Graduate Research Fellow | Clemson alum @ClemsonBioE @NanobioLab1 | she/her/hers 👩🏻‍🔬✨🧬

[nature @Nature]

Motherhood induces transcriptional changes in the brain that endure beyond short-term hormonal shifts

https://t.co/DIQcAVzKQ4

[Rice University News @RiceUNews]

A new advance against #OvarianCancer: Researchers at Rice and @UTMDAnderson report promising first-in-human results for implantable “cytokine factories�� that deliver immunotherapy at tumor location.

Supported by @ARPA_H, NIH and @CPRITTexas

Learn more: https://t.co/MbTtZA6yt0

[Nature Reviews Drug Discovery @NatRevDrugDisc]

The landscape for therapeutic cancer vaccines
https://t.co/EK4oljSHbx

This new article analyses the pipeline of clinical-stage therapeutic cancer vaccines, including the technology platforms, antigen selection and personalization approaches

[Mike Mitchell @MJMitchell_Lab]

Check out our latest in @NanoLetters led by @MJMitchell_Lab Postdoctoral Fellow @DongyoonKim5 and PhD student So-Jeong Moon on an HIV envelope–inspired T cell transfection-enhancing (HITE) lipid nanoparticle platform for CAR-T cell engineering!

Link: https://t.co/raRs9slfIQ

[Penn Engineering @PennEngineers]

In @NatureMaterials, the lab of @MJMitchell in @pennbioeng redesigned lipid nanoparticles to boost mRNA vaccine performance while reducing common inflammatory side effects, thanks to chemistry that revs up the metabolism of immune cells.

https://t.co/t7Nlr3aa2e

[Mike Mitchell @MJMitchell_Lab]

Thrilled to share our latest in @NatureMaterials led by @MJMitchell_Lab Postdoctoral Fellow @DongyoonKim5 on a new class of cross-linked ionizable lipid-like materials that reprogram immune cell metabolism for potent mRNA LNP vaccines!

Free access: https://t.co/71lF2tGB90

[Nature Reviews Bioengineering @natrevbioeng]

Engineering considerations for paediatric drug delivery https://t.co/4vhIXlwIUl

[Nature Reviews Bioengineering @natrevbioeng]

Integrating sex as a biological variable should not be viewed as a women’s health concern but as a requirement for reproducible, rigorous research that ultimately benefits everyone. But what does truly meaningful integration look like in practice?
https://t.co/JTo8pONQcM

[Science Magazine @ScienceMagazine]

In a new Science study, researchers report that the limited number of remaining follicles of aged mice and women with premature ovarian insufficiency can be stimulated to grow and develop by modulating the stroma, the amorphous substance that surrounds them.

This finding has potential implications for treating infertility. Learn more in a new #SciencePerspective: https://t.co/UybgnVhhtq

[Alex Hamilton @a_hmltn]

Thrilled to share the final installment from my Ph.D. research @MJMitchell_Lab! Featuring high-throughput screening using molecular barcoding, a cancer vaccine model, and new tools to evaluate LNP protein corona formation!

Read it in Advanced Materials: https://t.co/Qji4plz4ng

[Mike Mitchell @MJMitchell_Lab]

Check out our latest in @acsnano led by @MJMitchell_Lab PhD student @_emilyhan_ in collaboration with @EliLillyandCo @SeanBedingfield on high-throughput in vivo screening via mRNA barcodes to identify LNPs for systemic mRNA delivery to the brain!

Article: https://t.co/trcXfbgQo4

[Mike Mitchell @MJMitchell_Lab]

Check out our latest review article in Materials Today led by @MJMitchell_Lab Postdocs Soyeon Yoo and Melgious Ang along with PhD student @AmandaMMurray14 on engineering targeted RNA lipid nanoparticles for treating diseases beyond the liver!

Free access: https://t.co/sSPaXgSo3u

[Nature Reviews Bioengineering @natrevbioeng]

Designing nanomedicine to overcome therapeutic challenges in pregnancy https://t.co/aC0OExEaJ2

[Mike Mitchell @MJMitchell_Lab]

Had a blast at our inaugural @Dan_A_Heller @MJMitchell_Lab joint lab apple picking event @TerhuneOrchards! Great team bonding and collaboration building. We look forward to making it an annual tradition!

[nature @Nature]

People being treated for certain deadly cancers lived longer if they had received an mRNA-based vaccine against COVID-19 than if they hadn’t

https://t.co/ZR3tYeHElg

[Mike Mitchell @MJMitchell_Lab]

A surprise bonus from COVID-19 vaccines: bolstering cancer treatment | Science | AAAS https://t.co/T47ND5hgf4

[Mike Mitchell @MJMitchell_Lab]

Great to see @MJMitchell_Lab Professors and future Professors reunite @BMESociety! Check out @MagBillingsley's poster at 10am and @SwingleKelsey's talk at 245pm in Room 29C today, and @hannahyamagata @AmandaMMurray14 are on deck tomorrow with exciting mRNA LNP talks! #BMES2025

[Penn Bioengineering @pennbioeng]

Applying to the BE Ph.D. program? Get matched with a current Ph.D. student for 1:1 mentorship through our Applicant Support Program, from interview prep to insider insights about the process.
Apply by Oct. 31st (AOE): https://t.co/eIvOGKV4m7
@pennengineering @PennEngGrad

[Mike Mitchell @MJMitchell_Lab]

The @MJMitchell_Lab is off to sunny San Diego for #BMES2025! Come check out amazing talks by @AmandaMMurray14 on ovarian cancer immunotherapy, @hannahyamagata on ultra specific mRNA LNP vaccines, and Ben Nachod on steroid lipid nanoparticles to treat autoimmune disease!

[nature @Nature]

The gut microbiota is essential for maintaining female fertility

https://t.co/xCmW2dujV5