A degenerative disease of the joints, #osteoarthritis affects 50% of people over 65, with the biopsychosocial impact often overlooked. I'm grateful to be a part of the fight against this debilitating disease. https://t.co/EKRgcFIt1F
.@Amandality@UHN_News - A devoted granddaughter witnessed the decline of her grandmother due to #osteoarthritis and dedicated her career to finding a solution https://t.co/jZucTLOSMz #Canada150
Monthly #OARSI ECI Publication: @Amandality and her team identified miR-126-3p as a promising biomarker for knee #OA. It reduces angiogenesis and mitigates disease severity, supporting its potential as a therapeutic target.
Read the paper here: https://t.co/Rx3Kw9lzKa
Excited to share our research on microRNA-126-3p in @NatureComms! We found this microRNA is elevated in four knee osteoarthritis cohorts and show in an animal model that it reduces the severity of knee osteoarthritis - at least in part via angiogenesis. https://t.co/maiOg8klK3
When asked to draw a scientist, school-age kids in the United States are increasingly sketching women, according to a study from 2018.
Read more on #WomenInScienceDay: https://t.co/gv6TDrdT4r
Today is the 10th International Day of Women and Girls in Science #IDWGS!
Diversity in science benefits everyone! At CIHR, we’re proud to support women researchers at every career stage, including through programs like the REDI Award: https://t.co/evet2RjKKe
Congratulations to Reshani, an outstanding DLSPH student @UofT_dlsph previously working with Osvaldo Espin-Garcia @WesternU, Jackie Whittaker @jwhittak_physio and I to better understand physical activity patterns in those with knee osteoarthritis.
New publication alert! 📣 A team effort by Amanda Ali, Johanne Martel-Pelletier, & Osvaldo Espin-Garcia using integrated machine & deep learning to undercover microRNAs associated with knee osteoarthritis structural progression, now in @OACJournal here: https://t.co/N40URTA6hq
Comparison of definitions of early knee osteoarthritis for likelihood of progression at 2-year and 5-year follow-up: the Multicenter Osteoarthritis Study… “Most knees with early OA are stable and do not progress.” Nice work @rheum_cat et al.! https://t.co/hzCJ7K0UHw
Grateful to be part of such a stellar team alongside Osvaldo Espin-Garcia @WesternU working on methods to improve our interpretation of genetic and epigenetic traits associated with #osteoarthritis - find our recent publication in @OACJournal here: https://t.co/SQ9kZghtZK
New publication alert! 📣 A collaboration to explore colocalization methods in osteoarthritis led by Osvaldo Espin-Garcia @WesternU and Amanda Ali @Amandality now published in @OACJournal - find it here: https://t.co/00YyUj8UM4
Remembering the first woman to be awarded a Nobel Prize, the first individual to be awarded two Nobel Prizes and still today the only individual with two Nobel Prizes in two different scientific categories: Marie Skłodowska Curie.
Curie was born #OnThisDay in 1867.
Restricting sugar exposure in the first two years of life can meaningfully reduce the risk of chronic diseases in adulthood.
We need to rethink many cereals, snacks, and treats for children.
https://t.co/P0cTOtpLNV
Did you know that ~50% of people that have a knee injury will develop #osteoarthritis within ~10 years? More importantly did you know there are things you can do about it? @soarknee@Aging_SMART@Arthritis_ARC
Just three weeks until our application deadline! We offer a unique fellowship that can have a direct impact on mental health care! DMs are open for questions!
The 2024 Nobel prize in physiology or medicine has been awarded to Victor Ambros and Gary Ruvkun, who discovered microRNAs, a class of tiny RNA molecules that help to control how genes are expressed in multicellular organisms. Read the @Nature article. https://t.co/Hc9wuaQY3s
Congratulations to our 2024 medicine laureate Victor Ambros ✨
This morning he celebrated the news of his prize with his colleague and wife Rosalind Lee, who was also the first author on the 1993 'Cell' paper cited by the Nobel Committee.
#NobelPrize
The Nobel Prize in Physiology or Medicine 2024 - https://t.co/CNGkkOdfQd ... jointly to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation!
I'm privileged to be studying the role of #microRNAs in #osteoarthritis.