Disappointing news in #HCC: the much-anticipated Phase 3 IMbrave152 trial (atezo/bev ± tiragolumab) has quietly read out negative
https://t.co/3oAdrGIiwO
Pathological response following neoadjuvant immune checkpoint inhibitors in HCC: a cross-trial, patient-level analysis
@TheLancetOncol
https://t.co/0vZEXh9Qxj
👉111 pts, 1.4 mo neoadj. 💊
👉MPR: 32%, PCR 18%
👉Best threshold 90%
🧐Neoadj ICI is the way to go
@ILCAnews@EASLedu@myESMO #livertwitter
[ILCA 2024]
Grateful to attend this very informative meeting and to listen to the experts’ discussions. Lots of discussions in the intermediate stage HCC space around Emerald-01 and LEAP-012.
[AACR/ASCO Methods in Clinical Cancer Research Workshop]
7/28-8/3/2024
Amazing learning and networking experience with the selected fellows and junior faculty all over the country.
New in @Nature from @SohrabShah, @sajraparicio & team: How cell-to-cell structural variation contributes to the origins of phenotypic and evolutionary diversity in triple-negative #BreastCancer and high-grade serous #OvarianCancer. https://t.co/QIwJj1MGfJ
MSK physician-scientist @CharlesSawyers & computational biologist @dana_peer led a team that shed new light on mechanisms by which prostate cancer cells can transform and resist hormone therapy, opening the door to new clinical approaches. Find out more. https://t.co/vhvpDVm7IU
See our latest work in rectal cancer. Genomic and transcriptomic determinants of response to neoadjuvant therapy in rectal cancer | Nature Medicine https://t.co/6PKEUlifhX
Killer T cells are beautiful! This high resolution/rapid acquisition video of a T cell attacking a lymphoma cancer cell was captured on a specialized Lattice Light Sheet microscope with the help of my wonderful collaborators @HHMIJanelia. See more details in the thread below.
In the 1st-line setting of advanced NSCLC 🫁, anti-PD(L)1 monotherapy has regulatory approval in tumors with high PDL1 expression (≥50%) while the chemo + IO combo is approved irrespective of PDL1 expression.
👇
It’s the last week of #2021! To round out the year, we’re sharing 10 clinical advances our amazing scientists and doctors made to improve the treatment of #cancer this year.
https://t.co/wefzOIoqCJ
First-in-Class Trial MCARH109, a GPRC5D Targeted CAR T Cell Therapy in Patients with Refractory Multiple Myeloma. Great results, even for patients treated previously with antiBCMA therapies. Amazing job Sham and @ESmithMDPhD GPRC5D rocks! @sloan_kettering #ASH21@ASH_hematology
🚨 #ASH21 News - Results from the first-ever trial for a new class of #leukemia drugs called menin inhibitors are encouraging. Read more: https://t.co/0mkiFH1uhz
This year, MSK’S own @YJanjigianMD led not one, but two clinical trials resulting in FDA authorizations for two treatments that can give hope to some gastric and esophageal #cancer patients. Read the full story here. #StomachCancerAwarenessMonth
https://t.co/ifFSGirsiO
Circulating Tumor Cell‐Based mRNA Scoring System for Prognostication of Hepatocellular Carcinoma ‐ Translating HCC Tissue‐based mRNA Profiling into a Non‐invasive Setting from @VatcheAgopianMD and colleagues. https://t.co/gvjGHLEc2X
I got to spend the week with this excellent team of residents rounding @sloan_kettering. Up next they get to round with DOM Chair. Thank you for covering the service this weekend Deb Schrag @debschrag. @MSK_MedChiefs@MSKEducation