Anna (Schrempf) Hanzl

Scientist to Strategist | Consultant at BCG Zürich | PhD in Molecular Biology at the Research Center for Molecular Medicine (CeMM), Vienna

[Anna (Schrempf) Hanzl @AnnaSchrempf]

@FerreiraSilvaJ @BKleinstiver Congrats, Jo!! ! So happy for you!! :)

[CeMM @CeMM_News]

Congratulations to Anna Schrempf, from the groups of former PI Joanna Loizou (@LoizouJoanna) & CeMM PI Georg Winter (@georg_e_winter), who has successfully defended her PhD thesis "Dissecting the role of Polymerase θ in #BRCA mutant cancers". Well done!🎉#phdlife

[Anna (Schrempf) Hanzl @AnnaSchrempf]

@MickeRzO @SaraBernardo__ Thank you Miguel, also for all your help! Team work is how science works best!

[Anna (Schrempf) Hanzl @AnnaSchrempf]

I am excited to share that my PhD project is out. Huge thanks to co-author @SaraBernardo__ and the entire crew that made this possible. POLQ rocks! Thread 👇

[Joanna Loizou @LoizouJoanna]

A big day for DNA gaps! We uncover a role for POLQ, a therapeutic target in BRCA mutant cancers, in single-strand DNA gap filling, led by @AnnaSchrempf, @SaraBernardo__. Huge thanks to collaborators @Vincenzo_IFOM @wiedermc @EckerGerhard @georg_e_winter
https://t.co/Uvpxzg7Z09

[Anna (Schrempf) Hanzl @AnnaSchrempf]

@giuliosf @LoizouJoanna @SaraBernardo__ @Vincenzo_IFOM @wiedermc @EckerGerhard @georg_e_winter @CeMM_News @MedUni_Wien Thank you Giulio!

[CeMM @CeMM_News]

In their new @CellReports paper, researchers from former CeMM PI & @MedUni_Wien Assoc. Prof. Joanna Loizou (@LoizouJoanna) demonstrate how inhibiting the POLΘ enzyme can stop the growth of #cancer cells with mutations in #BRCA1 ✂️🧬 ➡️ https://t.co/wkA6yyntso

[Anna (Schrempf) Hanzl @AnnaSchrempf]

@CrisMayorRuiz @IRBBarcelona @ERC_Research @AlejoFraticelli Congrats Cris, that's amazing!

[Joanna Loizou @LoizouJoanna]

We are hiring a lab manager 💻 If you are well-organized and proactive & want to contribute to the efficient running of our lab, join us ➡️ https://t.co/ADcJtNF8Ws! We are a dynamic, collaborative & interactive international team working on genome integrity in Vienna, Austria 🧬

[Joanna Loizou @LoizouJoanna]

Mutational signatures are the outcome of DNA damage, repair & replication in cancer. Check out our preview @CellSystemsCP on RepairSig, a computational model that deconstructs mutational processes in cancer genomes @SaraBernardo__
https://t.co/bhfSAeewuN
https://t.co/wbA7pDrYdw

[Joanna Loizou @LoizouJoanna]

6/6 These findings highlight how important it is to understand the #DNArepair mechanisms that underlie #genomeediting technologies. This work was led by two brilliant and talented scientisits @FerreiraSilvaJ & Goncalo Oliveira, in collaboration with Josef Jiricny

[Joanna Loizou @LoizouJoanna]

#CRISPR Here we shown that instead of being required for prime editing, the DNA repair pathway Mismatch Repair (MMR) attenuates it. So in the absence of MMR, efficiency and fidelity of prime editing are enhanced 🧬

[Zha Lab @zha_lab]

Welcome our 2021 Spring & Summer speakers to Social DNAing. Signup at https://t.co/q9gUMA4WR2 @LeungLab @Vincenzo_IFOM @JacksonMedapj @Spo11Rulz @CantorLab @LugerLab @yu_yonghao @nussenza @Chapman_lab_UK @LuLaboratory @chiolo_lab and more

[Joanna Loizou @LoizouJoanna]

Today we celebrate #WomenInScience, in our lab and across the world. Over the last year we have lived through trying times - not only a pandemic but the lab moved institute. Yet these strong women are still smiling. It's amazing to work with you all 👩🏽‍🔬🧪🧫🧬🔬 @WomenScienceDay

[Joanna Loizou @LoizouJoanna]

Today is #WorldCancerDay and we are committed to knowing how DNA damage is repaired to prevent cancer and how we can develop new chemotherapeutics. But this day is about the brave patients who are fighting this disease day in day out #IAmAndIWill @MedUni_Wien

[Anna (Schrempf) Hanzl @AnnaSchrempf]

@PaulaGuper ahh look at this!!!! Remember all these graphs with text boxes containing stars?

[Joanna Loizou @LoizouJoanna]

We've had the first snow which means Christmas is nearly here🎄🎅But we are celebrating differently this year with a lab quiz thanks to our wonderful postdoc Jana @Jana79849530. So from our lab to yours, we wish you a restful Christmas and may 2021 be all that 2020 was not!

[Joanna Loizou @LoizouJoanna]

The DNA polymerase POLQ is synthetic lethal with other DNA repair genes in cancer. Our review on targeting POLQ in #Cancer therapy is now online @trendscancer #openaccess. Written by our talented team members @AnnaSchrempf and @Jana79849530. Full article👇
https://t.co/wMVNeti4Is

[Anna (Schrempf) Hanzl @AnnaSchrempf]

Are you interested in why the DNA-repair enzyme POLQ might serve as an attractive target in cancer therapy? Check out our brand-new review in @trendscancer! @Jana79849530 and @LoizouJoanna!

https://t.co/QzoMGculia

[Anna (Schrempf) Hanzl @AnnaSchrempf]

@HanaImrichova @NatImmunol @HolabUnil Congrats Hana! :)