Asif Ali

Postdoctoral Fellow, Biochemist, Molecular Biologist.

[bioRxiv Cell Biology @biorxiv_cellbio]

Organelles harbour pH gradients https://t.co/PJAz7bino0 #biorxiv_cellbio

[Asif Ali @Asifcellbio]

@Naam_kafi_hai Asif

[Elizabeth Wright @erwright73]

🔬❄️ The new Krios 5 from ⁦@thermosciEMSpec⁩ is looking sharp in its new Midwest Center for Cryo-ET lab ⁦@UWBiochem⁩ @UWMadisonCALS⁩ ⁦@UWMadison⁩! Increasing #cryoEM #teamtomo access for bioscience researchers with support from ⁦@NIH_CommonFund⁩ ❄️🔬

[Samrat Mukhopadhyay @SamratLabMohali]

What a terrific recognition of our research field!
Dirk Görlich (Max Planck Institute Göttingen) & Steven McKnight (UT Southwestern) received the Lasker Award for their work on low-complexity domains & their phase separation.
Read the perspective in PNAS:
https://t.co/mTYWZf1lGv

[Andy Truman PhD @TrumanLab]

Excited to share our new work "Dissecting the Cdc37 Co-chaperone Code: Functional Roles in Chaperone-Mediated Stress Adaptation" in press at the Journal of Biological Chemistry https://t.co/VRaayVKoX7 🔥🔥🔥

[Samrat Mukhopadhyay @SamratLabMohali]

Happy to share our community note published in Nature Communications. In this 14-page article (34 authors from 9 countries), we discuss current practices in biomolecular phase separation and hope it will be useful to the biomolecular condensate community.
https://t.co/UgwnvPpOk2

[Eric Betzig @Eric_Betzig]

MOSAIC lattice light sheet xy projection over 2+ hrs in human retinal pigment epithelial cells of endoplasmic reticulum remodeling (cyan) and transport of vesicles (yellow) containing β4-galactosyltransferase....

[Asif Ali @Asifcellbio]

@slavov_n This is amazing. And during stress when there is sudden halt of rRNA production triggers chaperone stirred condensation of orphan ribosomal proteins. Cells has planB ( preservation model) in stress situation. Here is the link of the study https://t.co/NbGqyl2XcX

[Asif Ali @Asifcellbio]

@declan_c9 This is exciting! It will be interesting to test if it’s reversible after stress and to explore the role of Sis1/Hsp70 in the process.

[Asif Ali @Asifcellbio]

Hey #condensate enthusiasts, We just wrote a perspective piece describing biomolecular condensation as a preservation mechanism for orphan proteins during environmental changes.

Preserve or destroy: Orphan protein proteostasis and the heat shock response https://t.co/X4Bz6HGhbU

[Nature Cell Biology @NatureCellBio]

☕️In this issue: A Comment on #VolumeElectronMicroscopy, standards in sample preparation and image acquisition for enhanced reproducibility and data reuse.
👉🏼https://t.co/MtPSaAwktI
https://t.co/4byS8hbBzH

[ShorterLab @ShorterLab]

Design principles to tailor Hsp104 therapeutics https://t.co/wBaTZhdA23

[D. Allan Drummond @dallandrummond]

Our recent work (led by @sammykeyport) on evolution of biomolecular condensation is now highlighted as a featured article (and is open access) 🔬 https://t.co/yjJcmpGFW6 https://t.co/dhomE7QtTe

[Molecular Cell @MolecularCell]

Online Now: Nucleolar stress caused by arginine-rich peptides triggers a ribosomopathy and accelerates aging in mice https://t.co/xFumIa2ast

[ShorterLab @ShorterLab]

Macromolecular condensation organizes nucleolar sub-phases to set up a pH gradient: Cell https://t.co/4E8Ijj5TiH

[Mitch Guttman @mitchguttman]

PRC2 is reported to bind RNA. Yet, genetic experiments have raised serious questions about their functional relevance. Our paper revisits the biochemical evidence supporting widespread PRC2-RNA interactions and finds that many of these do not occur in vivo. https://t.co/zFdzL6zzZh

[The University of Chicago @UChicago]

Need a quiet space to read, relax or work? Visit the Arley D. Cathey Learning Center in this "study with me" style video. High-vaulted stone ceilings bring a sense of grandeur to your study session, with a carefully curated mix of classical music. https://t.co/pZ7sRUMqG3

[Greg Pintilie @gpintilie]

amazing integrative study of coronavirus NL63, with cryoET, sub-tomogram classification and averaging (@chiulab, @SLAClab), glycan profiling by mass spec (@DocGatorDawg1), MD (@abhisekhsingha1), and functional infectivity assays (@JingJin10601360)
https://t.co/Dhp6rArvww

[Asif Ali @Asifcellbio]

We are on Cover, #Chaperone #Condensates. Framing Heat Shock response as Condensostasis rather than Proteotoxic.

[Nature Cell Biology @NatureCellBio]

👋Our November issue's live!
Cover: #chaperone #condensates

👉🏿Read: #MitochondrialMetabolism #neuron #mechanotransduction #PhaseSeparation #lipidhomeostasis #ribotoxic stress #genomestability #senescence #MitochondriaTransfer #DEI... & more!
https://t.co/CMLnZSTLPi

[Nature Cell Biology @NatureCellBio]

👋Our November issue's live!
Cover: #chaperone #condensates

👉🏿Read: #MitochondrialMetabolism #neuron #mechanotransduction #PhaseSeparation #lipidhomeostasis #ribotoxic stress #genomestability #senescence #MitochondriaTransfer #DEI... & more!
https://t.co/CMLnZSTLPi