Thank you to the thousands of CalR users for all the positive feedback. We are happy that your in vivo energy balance analyses just got faster and easier. We secretly made this tool to solve our own problems. Looks like it helped others too.
So proud of wife and partner @SarahFlierMD and all of her accomplishments being recognized tonight by the crohns and colitis foundation @CrohnsColitisFn this evening.
@Maratosflier@EricTopol@Nature They do measure metabolic rate and report binned and adjusted energy expenditure in Extended Data Fig. 2. It's hard to tell if torpor is happening, and they don't mention it. In all fairness, they present a ton of data in a strict word limit.
Say good morning to our new medicine laureate 🎉
Gary Ruvkun was woken up in the early hours to the news he had been awarded the 2024 Nobel Prize in Physiology or Medicine.
Stay tuned for our interview with him, coming soon.
The Yale MMPC-Live is delighted to offer an opportunity for free metabolism focused, preclinical grant reviews to New Investigators from historically marginalized backgrounds and at predominantly minority serving institutions (1/🧵)
How ridiculous that legacy metabolic phenotyping companies still normalize EE data by body mass! This approach has been discredited for many years & has polluted the biomedical literature for decades. Normalizing EE by body mass raised to the 0.75 power is even more absurd; an abuse of Kleiber's INTERspecific (NOT intraspecific) mass scaling exponent. For more details, see my definitive textbook on metabolic measurement, "Measuring metabolic rates: a manual for scientists", published by Oxford University Press. The best state of the art analytical routines for extracted data can be found in @Bankslab's https://t.co/SktxXqKLra.
Tuna has an incredible capacity for mitochondrial OXPHOS in muscle. How do we study it? This is our way -- thanks to Luke Mead and Ray. Just to add, the samples are incredibly tasty.
Tuna has an incredible capacity for mitochondrial OXPHOS in muscle. How do we study it? This is our way -- thanks to Luke Mead and Ray. Just to add, the samples are incredibly tasty.
His humor, scientific insights, and mentorship will be sorely missed. His support altered the trajectory of my career and that of many others. He was just so good. My thoughts go out to his family and everyone close to Dave.
Science has lost a giant of physiology and metabolism. Vandy has lost a true leader. I have lost a mentor, colleague, and dear friend. Those of us lucky to have known him will remember his dedication and his (odd) humor. Rest now @DHWasserman1 We will miss you.
Respirometry setups range from the simple to complex, so you want to be sure once the hard-earned data is collected to analyze it right! To help, check out the Do’s and Don’ts of data evaluation and reporting.
This is an exceptional opportunity for post-bacs interested in metabolism and metabolic disease. Research experience in Joslin-BIDMC/Harvard with stipend and benefits. Please apply or spread the word!! https://t.co/WF4DiAHZsf
hey indirect #calorimetry users! We've launched a new version of CalR to analyze your data. Test the beta version at https://t.co/mw2zpaoH4R. New features: improved visualizations, quality control analysis, statistical power, energy balance, and more. Free! Feedback wanted pls.