Francesco G. Barone, PhD

🔬 Postdoc @labyoule @NIH @NINDS | Former @WellcomeTrust PhD @LivUni | 🧠 Researching #Neurodegeneration, #Autophagy, #Drosophila | 📢 Views my own

[Francesco G. Barone, PhD @BaroneFraG]

I'm thrilled to announce that my 2nd first-author paper has been published in @LSAjournal. Huge thanks to my co-authors and the reviewers for their invaluable contributions. #NIX #USP30 #NBR1 #Pexophagy #peroxisome @LivUniISMIB @CCI_liv @wellcometrust

https://t.co/1ob0uipwNk

[Francesco G. Barone, PhD @BaroneFraG]

@BonifacinoJuan @DePaceRaffa Congratulations Juan!

[Cell Biology J-Club @cell_club]

Happy Golgi Day

[Journal of Cell Biology @JCellBiol]

Yue Xiong, Weihua Gao, Zelai Wu, Xiukui Gao, Qiming Sun et al. (@ZJU_China) present new mouse models for visualizing the selective degradation of #peroxisomes (#pexophagy) in living animals. https://t.co/hRQkeseeGq

[Trends Cell Biology @TrendsCellBio]

Organelle-specific signaling of cGAS–STING https://t.co/jLKd2kUL7j

[Juan S. Bonifacino @BonifacinoJuan]

Many thanks to Amelia Glazier and The Journal of Cell Science for including me in ‘First Persons’ through the decades – 100 years of notable scientists in The Journal of Cell Science https://t.co/ZjrhEqV92Z Happy to be in such great company!

[Nature Biotechnology @NatureBiotech]

Precise, predictable genome integrations by deep-learning-assisted design of microhomology-based templates https://t.co/r9DQgX2ci5

[Juan S. Bonifacino @BonifacinoJuan]

Excited to share our new review with @DePaceRaffa, @SaikatSls, @cd_w1 @NIH on the BLOC-1 and BORC complexes—key regulators of endolysosomal processes and linked to several genetic diseases #lysosomes #melanosomes #synapses #kinesins https://t.co/2rrsDwkOJ8

[John Lukens @LukensJohnR]

Inflammatory and anti-inflammatory cytokines bidirectionally modulate amygdala circuits regulating anxiety: @CellCellPress https://t.co/HOI963g5PD

[Francesco G. Barone, PhD @BaroneFraG]

Diverse routes to mitophagy governed by ubiquitylation and mitochondri... https://t.co/gqPsPsJALe

[Francesco G. Barone, PhD @BaroneFraG]

@_m_marcello @EuroBioImaging @LivUniCancer @livuniLivSRF Appreciate it, @_m_marcello - Great teamwork on this project - lightsheet microscopy + fluorescent Drosophila = a winning combo!

[Marco Marcello @_m_marcello]

It was a pleasure to collaborate with @BaroneFraG ! Great work, involving #lightsheet microscopy.
@EuroBioImaging @LivUniCancer @livuniLivSRF

[Hao Yin @HaoYin20]

Visualize global & tissue-specific #Pexophagy in #Drosophila 🤠
Pexo-QC
Pexo-Keima
SKL signal for translocation to #Peroxisome matrix

@BaroneFraG @Natsansor #OpenBiology 2025
https://t.co/3OIkykSwpl

Read the excellent🧵from 1st auth @BaroneFraG 👇
https://t.co/g9rFJgh6cw

[Natalia Sanchez-Soriano @Natsansor]

Interested in pexophagy? Check out our newly published work: we developed pexophagy reporters for use in Drosophila research. Very happy to have been involved in this collaboration @LivUniISMIB
https://t.co/aJ5jBKlVzZ

[Francesco G. Barone, PhD @BaroneFraG]

8/8
Explore our findings! 📄
Read the full paper here: https://t.co/uDsdkTSebK
Published in @RSocPublishing #OpenBiology
Big thanks to my collaborators and mentors for their incredible support. Questions or feedback? Let’s discuss! #ScienceTwitter #Autophagy #Pexophagy @LivUni

[Francesco G. Barone, PhD @BaroneFraG]

1/8
🚨 New publication alert! 🚨
We developed live #Drosophila melanogaster models with fluorescent reporters to study #pexophagy – the selective autophagy of peroxisomes – in vivo. 🧵👇 @livuninews @wellcometrust @CCI_liv @LivUniHLS

[Francesco G. Barone, PhD @BaroneFraG]

7/8
Applications:
These tools enable precise genetic and chemical manipulation of pexophagy, paving the way for studying disease mechanisms (e.g., neurodegeneration) and cross-talk between organelles like mitochondria and peroxisomes.