Nephrologist in Vijaypura (BLDE) . . Alumnus #SGPGI Lucknow, Internal medicine (GMC and JJH, Mumbai) . . From #Karnataka . . tweets reflect personal views
@SethiRenalPath sir, how common is double positivity of PLA2R and NELL1 antigen in membranous nephropathy . . I had 2 young patients with both positivity . .
Regards
Dr Basavaraj Sajjan
Nephrologist
@SethiRenalPath sir, how common is to see both c3 and c4 low in Post infectious GN (or IRGN) . . I have 7yr old kid with Acute nephritic syndrome with low c3 and c4 . . ANA negative . . With Kidney biopsy s/o PIGN. .
🆕New @goKDIGO Guidelines 2024 of lupus nephritis
For Class 3/4 lupus nephritis
Steroids + either of below
1️⃣MMF
2️⃣low dose cyclophosphamide (pts with compliance issues to MMF)
3️⃣Belimumab+MMF
4️⃣CNI+MMF(pts with nephrotic range proteinuria and preserved renal fxn)
⤵️Reduced steroid dosage for LN
https://t.co/Q53o0OOcjG
🔴Anti-Diabetic Drugs - Dosing in CKD⤵️
🔸️As per latest recommendations Dapagliflozin can be initiated at eGFR > 20 and continued till RRT.
🔸️Also pioglitazone doesn't require dose adjustment for any stage of CKD.
️https://t.co/fqXOmz1oBW
#FOAMed#MedEd#medstudent
AKI due to snake envenomation
1. Contributory factors:
- Intravascular haemolysis
- DIC
- Direct nephrotoxicity and
- Hypotension and
- Rhabdomyolysis
Management aspects:
◦10 vials of polyvalent ASV stat over 30 minutes as infusion, f/b
◦6 vials 6 hourly as bolus therapy
2.Within first 24 hours of the bite- a trial of forced alkaline diuresis can be given
3.Indications for dialysis are:
•Absolute value of Blood urea >130 mg/dl or (BUN 100 mg/dl)
•Sr. Creatinine > 4 mg/dl OR
•Evidence of hyper-catabolism
• Pulmonary oedema