BaslerLab

Lab of Professor @KonradBasler, @UZH_en. We investigate diverse aspects of cell-cell communication in development and disease. Tweets are from lab members.

[bahar degirmenci @bahardgrmenci]

First Preprint from BD lab! 🚀
I’m beyond excited to share our ENS-Rich Assembloids (ERAs) - a breakthrough tool for studying the Enteric Nervous System (ENS)! 🔬🧫 @ilkesarii @nurik__satlykov @TomasValenta13 @belizuzun
Check it out 👉https://t.co/UfqpJjc3at

[TomasValenta @TomasValenta13]

Highly recommended to read. New ERA (see in the preprint what does it mean). Great work. I was honoured to participate a little bit. Congratulations to entire BD team, especially to Bahar.

[Hassan Fazilaty @HassanFazilaty]

Exciting new findings reveal eosinophils as key allies in the fight against colorectal cancer by blocking tumor spread.
Great work by Kristina Handler, Deeksha Raju, @AlessandraGurt1 & team lead by the amazing Isabelle Arnold @lab_arnold! Honored to be a part of this study. 👇

[Hassan Fazilaty @HassanFazilaty]

For a quick summary of our latest preprint, check out @TDalessi's thread! She breaks down our key findings on #Oncoembryology and the role of SoxC transcription factors in cancer and development.

[Hassan Fazilaty @HassanFazilaty]

From embryo to adult and back again!
In our latest preprint, we introduce oncoembryology—a parallel analysis of embryonic development and cancer. With my talented PhD student @TDalessi, we explored the fascinating connections between these two processes.
https://t.co/QL5PDwLgx0

[TomasValenta @TomasValenta13]

Check out the latest preprint from our lab. Great work lead by @HassanFazilaty and done mainly by @TDalessi. Many thanks to all coauthors. I was privileged to help with this nice work a little bit. Classics as Krebs and Virchow were right.

[Tosca Dalessi @TDalessi]

Huge thanks also to all other co-authors from @BaslerLab @vandenBroek_Lab @randall_platt lab and others & to @KonradBasler for supporting this work!

[Hassan Fazilaty @HassanFazilaty]

This was possible thanks to many, especially immense support of @KonradBasler, @BaslerLab members, @TomasValenta13, @gimoro_science, @MDBScience, collaborations with @vandenBroek_Lab and @randall_platt, and critical input from @George_Hausmann, @markrobinsonca, and many others!

[BaslerLab @BaslerLab]

Looking for a quick overview of our latest work on #Oncoembryology? Check out @TDalessi’s thread for a great summary of our discoveries on SoxC transcription factors and colorectal cancer.

[Tosca Dalessi @TDalessi]

Very happy to share our newest preprint! By leveraging embryonic development, we found that SoxC transcription factors are crucial drivers of colorectal cancer.

Thanks @HassanFazilaty for initiating and supervising this fascinating project!

[Tosca Dalessi @TDalessi]

Very happy to share our newest preprint! By leveraging embryonic development, we found that SoxC transcription factors are crucial drivers of colorectal cancer.

Thanks @HassanFazilaty for initiating and supervising this fascinating project!

[BaslerLab @BaslerLab]

Exciting new preprint from our lab led by @HassanFazilaty and the PhD work of @TDalessi, introducing #Oncoembryology!

[Hassan Fazilaty @HassanFazilaty]

From embryo to adult and back again!
In our latest preprint, we introduce oncoembryology—a parallel analysis of embryonic development and cancer. With my talented PhD student @TDalessi, we explored the fascinating connections between these two processes.
https://t.co/QL5PDwLgx0

[Claudio Cantù @ClaudioCantu81]

We present
The Transcription Factor Binding Landscape of Mouse Development🐭🧬 #DevBio

We use CUT&RUN-LoV-U to map
Many SignalingPathways X 4tissue X 2stages

It is a huge dataset - yet only the beginning of the
TranscriptionFactorBinding(TFB)-OMICS

https://t.co/E6ylRK8LE8

[Hassan Fazilaty @HassanFazilaty]

@NietoAngela Nice summary of this work by
@DirenaAC!

[TomasValenta @TomasValenta13]

Congratulations! Great and very important piece of work. It was very inspiring and stimulating to help @cocoborrelli and @moorlab lab a little bit. The discussions we had together are kept in my memory. https://t.co/b6IQ9HWh9C

[Hassan Fazilaty @HassanFazilaty]

One exciting aspect is discovering the link with EMT-MET dynamics and epithelialization in carcinomas. Ocaña and colleagues from @NietoAngela's lab first showed epithelialization is necessary for metastasis. 12 years later, the role of microenvironment in this process is clearer.

[Hassan Fazilaty @HassanFazilaty]

We've long sought to understand the biology of metastasis. Today, in this fantastic work from @cocoborrelli and others mainly from the @moorlab, read about an elegant study explaining the mechanism of metastatic colonization. Honored to be part of this groundbreaking research!

[Andreas E. Moor @AndreasMoor]

How are cell-cell interactions governing successful metastatic colonization in the liver? Have a look at our new paper in @nature that introduces an in vivo proximity screen to functionally test cellular interactions in a high-throughput manner. https://t.co/oWFn3Hfj8M 🧵

[MoorLab @moorlab]

Check out our lab's latest paper out in @Nature! Congrats to @cocoborrelli and everybody involved 🎉🥳

[Hassan Fazilaty @HassanFazilaty]

Inspiring lecture by @HansClevers for the first #CharlesWeissmann award from Department of Molecular Life Sciences, @UZH_en.
Also it was amazing to have Prof. Weissmann himself present at the ceremony, a true pioneer of molecular biology in Zurich!

[Claudio Cantù @ClaudioCantu81]

Please RT:

Join to the #PALSSummerSchool2024
in #transcriptomics 🧬🪰🐭🧪

I promise an unforgettable experience with top scientists in the 🌍

Registration open until 🚨May 17th🚨
will likely close before due to limited spots🪑

Check it out!
https://t.co/d92pgfSkQ4