BauschLab

[alfredosciortino @alf_fonsi]

We study membrane and microtubules fluctuations using flickering spectroscopy, simulations and theory. The main message: the MTs push on the membrane and deform it, but are deflected by this soft boundary and hence "transport" the deformations along the membrane creating "waves"

[alfredosciortino @alf_fonsi]

New preprint 🔥 my PhD swan song, with @BauschLab @hamfaizi @PVlahovska @HaganLab (+ Matt, Sarvesh Layne & Aparna)
https://t.co/uVaq6sgNsq
We put a microtubules+kinesin gel inside a GUV and... this happens: crazy fluctuations of a "cell" induced by a "minimal cytoskeleton"!

[3D Matter Made to Order @Cluster3DMM2O]

The next speaker of our #Future3DAM Cluster Conference 2024 is Andreas Bausch from @TU_Muenchen. He will present recent results on Structure Formation in Organoid Systems, explaining why Activity Matters. Register now! https://t.co/CvdxBdndFA #organoids #researchconference

[Lammerding Lab @LammerdingLab]

(1/3) How do cells squeeze their large nucleus through tight spaces? In work led by @JeremyKeys92 and in collaboration with @mingmingwu2 (now at @biorxivpreprint) we found that cells can push their nucleus by pressurizing their rear (video - left):
https://t.co/oqh943RbBC

[BauschLab @BauschLab]

Enjoy the beautiful branched structure with a lumen!

[BauschLab @BauschLab]

Beyond spheroids!
We show #PancreaticCancer cells self-organize into morphologically-faithful #organoids! Great work by Samuel, @arispapargyriou from @MaxReichert lab and @EdouardHannezo for a true collaboration between Biohysics and Medicine!
https://t.co/qIGPJEBcbl

[BauschLab @BauschLab]

Enjoy how they invade!

[Lotta Lorenz @LottaLrnz]

If you ever need an overview of measurement methods of network #mechanics, here's a suggestion 😎 (Fig. 3 in our review) #Teaching
Including work by @BauschLab @SchmollerLab on how actin networks with alpha actinin form bundles and stiffen after repeated shearing.

[TimonNK @NkTimon]

My first paper is out now. 🎉 We reconstitute the formation of VASP condensates on bilayers, which nucleate, polymerize and bundle actin filaments. The bundles grow by enhanced polymerization aligned to filaments.
Thanks to @BleicherPhilip, @MarcoPayr and of course @Bauschlab.

[Laurent Blanchoin @Lblanchoin]

Ondrej’s article appeared today in PNAS. I hope you enjoy reading this updated version.

[Edouard Hannezo @EdouardHannezo]

Happy to see this fun collaboration out! Scroll down for more on the dual encoding of patterning and mechanics by morphogens, to preserve patterns throughout complex 3d morphogenesis!

[alfredosciortino @alf_fonsi]

Very nice..! And reminding of gliding systems with steric constraints!

[alfredosciortino @alf_fonsi]

New paper out in @NatureComms: polar patterns of filaments gliding *on a sphere*🌐https://t.co/1U0kQJDo9M A project from my PhD I love, with co-first Chiao-Peng and our old student Alice. Here a [long!] thread, with a bit of backstory, results, discussion and...cool movies!🧵1/22

[SerwaneLab @serwanelab]

Good stuff

[Ondrej Kucera @OndrejDrKucera]

Make a dough and let it rise;
observe it to self-organise.

Don't forget to mention, though;
it is an MT-actin dough.

Our minds are very bright;
we made a smart composite.
We are writing history;
the composite has memory.

https://t.co/jcmeCiTtJT

[Xavier Trepat @XavierTrepat]

Less than one week to submit an abstract! 👇

[David Brückner @d_brueckner]

🔥NEW PREPRINT🔥

How are collectively migrating cells constrained by the curvature & topology of 3D systems?

We discovered a collective velocity wave propagating in such a system & show that it emerges as a response of active matter to curvature

👉 https://t.co/Dr700IsfY2

[Steph Vassilopoulos @Biosdfp]

🎉Glad to see this one published:
Microtubules tune mechanosensitive cell responses
https://t.co/qPwiYChDcF
congrats to all authors and thanks @etiennemannevil and @shailajaseethar for the opportunity to image beautiful migrating astrocytes 🔬

[BauschLab @BauschLab]

And they do rotate ! Collective cell motion drive the self organization of mammary gland organoids structures https://t.co/beWgwtjfR8