Michael Baym

Microbiology, evolution, antibiotic resistance, applied math, molecular biotech. Associate Professor @HarvardMed. Basic research is the engine of progress

[Michael Baym @baym]

@nquinoneso and @implosian made a logo for our lab and it's incredible. I can't get over it

[Dan Landau @landau_lab]

Exciting breakthrough technology from the lab, now live in @CellCellPress ! Instead of cutting the genome where proteins bind (e.g., Cut&Tag), D&D-seq scars the DNA with a deaminase, allowing single cell genome mapping of TFs and chromatin remodellers!

[Michael Baym @baym]

@neal_amin It's true, 8x13 would have been closer to the golden ratio, and a more perfect plate

[Michael Baym @baym]

You: The world needs more bioproducts
Me: Behold, the biblically accurate 96-well plate

[Michael Baym @baym]

@ThatMrE

[Michael Baym @baym]

@nandgatesonly @ivandjrueda Pinning 384 to 1536 like

[Michael Baym @baym]

@theproteindance be not afraid

[Michael Baym @baym]

@SynBio1 needs more eyes

[Heidi Klumpe @HeidiKlumpe]

The preprint from my work @MoKhalilLab and @DunlopLab at BU is out on bioRxiv! As new tools come online to engineer multicellularity, we asked: how does sticking cells together into larger groups affect their fitness and function?

[Ginkgo Bioworks @Ginkgo]

Excited to be named a launch partner for @Microsoft Discovery, now generally available as announced at @MicrosoftBuild. Researchers will soon be able to plan experiments in Discovery and run them directly on Ginkgo Cloud Lab.

Keynote (jump to the Discovery segment): https://t.co/yHvokj40Vl

Microsoft's announcement: https://t.co/Ucyb5OENGG

[Paul Bollyky @bollyky]

Good news! The @NIH and NIAID have created the Centers for Accelerating Phage Therapy to Combat ESKAPE Pathogens (CAPT-CEP). Here at @StanfordDeptMed we are so excited to be part of this program with @PittTweet and @GladstoneInst

[Sarafina El-Badry Nance, PhD @starstrickenSF]

This standing ovation totally brought me to tears.

On Thursday, my dad (stage 4 pancreatic cancer) started a Revolution Medicine trial building upon these results — RMC 5127, which uses the drug celebrated here, Daraxonrasib, with another drug targeting his specific KRAS mutation, G12V.

He’s nearly 2 years into his fight with pancreatic cancer and we have personally felt the impact of this watershed moment. It is a lifeline.

To the incredible, stalwart, brilliant researchers and folks bringing these discoveries to life - thank you. Thank you thank you thank you.

[Ethan J. Weiss @ethanjweiss]

As a non-oncologist, i feel quite comfortable jumping on the bandwagon here. I can count the number of times I've seen unsolvable problems in medicine get solved in my lifetime. No, this is not a cure, but there has been no greater challenge than pancreatic cancer. Nothing worked. Now this...

These results are simply spectacular

Daraxonrasib or Chemotherapy in Previously Treated Metastatic Pancreatic Cancer | New England Journal of Medicine https://t.co/a52WwDQ2Ju

[Mayor Zohran Kwame Mamdani @NYCMayor]

Today, I signed an Executive Order temporarily repealing bedtimes in the City of New York so that kids of all ages can watch our team in the NBA Finals.

As Mayor, you’re forced to make many difficult decisions. This was not one of them.

Go Knicks.

[Matt Herdman @MattHerdman]

Happy Pride month to the whole LGBTQNJ+ rainbow!

[Michael Baym @baym]

I will always love the aesthetic of “let’s take biology and make it bigger”

[Ali H. Shaib @AliHShaib]

Hello world, meet 1,000× Expansion Microscopy.
1,000,000,000× expansion by volume! A gel that starts at a few centimeters will then expand to the volume of an Olympic swimming pool. https://t.co/E43kxx4O5M
In our new bioRxiv preprint, work carried out between MIT and UMG, led by Helena Hu in collaboration with scientists from the labs of @eboyden3 Ed Boyden, Silvio Rizzoli, and myself, we present Thousandfold Expansion Microscopy.
By enlarging biological specimens across multiple rounds of expansion, molecular-scale features, as small as the distances between adjacent amino acids, can be visualized with conventional optical microscopes.
Democratizing super-resolution microscopy.

[Michael Baym @baym]

@hhlee we love a lorge plate

[Eric Topol @EricTopol]

Another major advance vs cancer! @ASCO #ASCO26
Personalized neoantigen mRNA vaccine 5 year follow-up vs metastatic melanoma reduced recurrence and death by 49% (on top of Keytruda)
https://t.co/NadITTYIT2

[NEJM @NEJM]

Presented at #ASCO26:

Among patients with previously treated metastatic pancreatic ductal adenocarcinoma, the RAS(ON) inhibitor daraxonrasib led to significantly longer overall survival and progression-free survival than chemotherapy. Full phase 3 RASolute 302 trial results: https://t.co/xwLWBZYRzq

@ASCO

[Patrick Hsu @pdhsu]

people aren’t celebrating this pancreatic cancer breakthrough enough. it should be international news

[Tyler Jankoski NBC5 ☀️ @TylerJankoski]

The meteor on Saturday was spotted as far away as Canada and appeared on several radar scans. Based on an extensive analysis of all available radar data, if any debris reached the ground, it would be in Cape Cod Bay, north of Barnstable and west of Eastham. (1/3)