Benny Chain

Immunologist at UCL

[Benny Chain @BennyChain]

Can now run the whole pipeline using a single command. Much faster and more memory efficeint.

[Benny Chain @BennyChain]

For all the T cell receptor sequencers out there, the latest version of our analysis pipeline Decombinator 5.0 is live, and now on PiPy for greater ease of installtion ! Thanks to Matt Cowley for a huge amount of work !
https://t.co/PeaXbmbUkt

[Benny Chain @BennyChain]

For all the T cell receptor sequencers out there, the latest version of our analysis pipeline Decombinator 5.0 is live, and now on PiPy for greater ease of installtion ! Thanks to Matt Cowley for a huge amount of work !
https://t.co/PeaXbmbUkt

[The Francis Crick Institute @TheCrick]

We are delighted to announce that Professor Edith Heard has been appointed as our new director and chief executive!

Edith, who is currently director-general at @EMBL, will succeed Paul Nurse in leading the Crick from the summer of 2025.

🔗 https://t.co/CcJR4TFxbF

[Benny Chain @BennyChain]

Single cell analysis of the phenotype of bonemarrow T cells in myeloma reveals striking phynotypic differences from solid tumour TILS. Read our latest paper out here https://t.co/faW0dqIvwA

[Weizmann Institute @WeizmannScience]

Are you a PhD graduate in Physics, Chemistry, Earth Science, Math or Computer Science?

Apply for the Max Planck-Weizmann Joint Postdoctoral Program. Includes a fully funded four-year position, split equally between these two esteemed institutions >> https://t.co/cCmnYaanVs

[Christopher A. Baker @bakermind]

New major team preprint demonstrating antibodies from #longCOVID patients are sufficient to cause pathology and behavioral symptoms when transferred to mice. Importantly, they match individual patient symptoms to potential autoantigen targets and induced mouse behaviors

[Dr Vicky Enne 🇪🇺 @Beat_AMR_Bugs]

@UCLInfectImm 👏👏👏 Fantastic, well done Paul. A great man.

[Mahdad Noursadeghi @mnoursad]

We're hiring! Are you a lab scientist interested in human immunology of infectious disease, using cellular models of host-pathogen interactions and human experimental challenge, focusing on immune responses in Tuberculosis and SARS-CoV-2? Apply here: https://t.co/sieGz7EEVw

[Benny Chain @BennyChain]

The latest exciting step forward in T cell receptor representation ! @YutaNotUtah outperforms TCR-BERT ! https://t.co/1OMhRsckRw

[Benny Chain @BennyChain]

We are looking for a research fellow interested in the T cell receptor repertoire to work on some amazing cancer data sets. Check out this job at UCL: https://t.co/lBF0QUUCNl

[Andreas Tiffeau-Mayer @andimscience]

How do interactions between hypervariable loops shape TCR specificity? Can patterns of sequence co-variation help us pair alpha-beta chains using techniques developed for co-evolving proteins?

New work led by @Martina_Milig now out on bioRxiv! 👇

[Benny Chain @BennyChain]

Martina's elegant new paper defines an important and under-appreciated role for molecular interactions between CDR loops of the TCR !

[bioRxiv Immunology @biorxiv_immuno]

Intra- and inter-chain contacts determine TCR specificity: applying protein co-evolution methods to TCRαβ pairing https://t.co/EgXU8g4Jvr #biorxiv_immuno

[Nature Microbiology @NatureMicrobiol]

OUT NOW 📢: A folate inhibitor exploits metabolic differences in Pseudomonas aeruginosa for narrow-spectrum targeting @zgitai1

https://t.co/zSC20CdMn4

[zgitai @zgitai1]

So excited for our latest story on a tunable-spectrum antibiotic to be published. We desperately need microbiome-sparing strategies to treat P. aeruginosa. Amazing effort led by the fantastic @ConnorChain

[Andreas Tiffeau-Mayer @andimscience]

Lightning-fast adaptive immune receptor similarity search by symmetric deletion lookup
https://t.co/3uqZF9AyMF

In work led by @heartnetkung we show how an algorithmic paradigm from spell checking can accelerate TCR clustering by orders of magnitude

[Andreas Tiffeau-Mayer @andimscience]

Three weeks left to apply to our open-rank search in AI & Infection! Come join us at @UCLInfectImm 😀

[Quezada Lab @QuezadaLab]

The Arthur and Sandra Irving Cancer Immunology Symposium
Website: https://t.co/10GJFFSMZl
Hosted by Arthur and Sandra Irving symposium (from Jun 24-27, 2024 in Boston) will focus on advancing the careers of young scientists doing research in cancer immunology. Apply!!!

[Andreas Tiffeau-Mayer @andimscience]

Glad to announce that our QImmuno lab approach for TCR-pMHC specificity prediction just won silver and bronze medals in the IMMREP23 benchmark! 🥳
https://t.co/8plXf23LgV

[Benny Chain @BennyChain]

This seems a cool paper - proteins in the shapes of letters or digits !! https://t.co/E0GDl3Z5yj

[Renato Ostuni @OstuniLab]

💥BIG PAPER ALERT💥 So excited to share our latest, out now @Nature! Here, we uncover a spatially confined interplay between subsets of IL-1b+ macrophages and tumor cells that fuels pathogenic inflammation in pancreatic cancer (1/n)
https://t.co/sbazVYXVXk