Benoit Pugin

Gut microbiota research; ETH Zürich

[Benoit Pugin @BenoitPugin]

Proud to share our protocol for cultivating human #GutMicrobiota ex vivo! Special thanks to Janina Zünd for her key contribution! We've streamlined the cultivation process for maximum flexibility and throughput while ensuring high reproducibility (1/3) https://t.co/8IdrhY9zjQ

[Benoit Pugin @BenoitPugin]

@Ella_Maru Thanks, Ella! I doubt the sensitive taxa can serve as biomarkers when considered individually. For example, L. eligens is present in ~3/4 of human guts, and R. gnavus includes both sensitive and resistant strains. It might be different when looking at combinations

[Benoit Pugin @BenoitPugin]

We provide a tolerance profile of gut microbes to oxidative stress and reveal previously overlooked sensitive taxa: L. eligens and F. saccharivorans https://t.co/9VxxLaEObf

[Benoit Pugin @BenoitPugin]

@SoheilSaeedi5 Thanks Soheil ! Highly appreciated ! :)

[Benoit Pugin @BenoitPugin]

Interestingly, we previously showed that L. eligens is an important contributor to gut ILA. Taken together, this could explain the reduction of IPA in diseases associated with gut inflammation
https://t.co/5ipIPemf0o

[Benoit Pugin @BenoitPugin]

@AHarms485 @hauryliuk 🤤

[Benoit Pugin @BenoitPugin]

@SoheilSaeedi5 @NatureAging Thanks for leading this study, Soheil! Really glad we teamed up on this! 🙌

[Soheil Saeedi @SoheilSaeedi5]

🚨Just published in ⁦⁦@NatureAging⁩!

🧬 We discovered that a gut #microbiota-derived metabolite, phenylacetic acid (PAA), accumulates with age and triggers endothelial #senescence, a key driver of cardiovascular #aging.

#Saeedi_Lab

➡️ Read more https://t.co/oXfwRwrMzS

[Benoit Pugin @BenoitPugin]

We identified new gut bacteria producing ILA and IPA: Lachnospira eligens and Enterocloster aldenensis. 🙌
We also highlight the importance of cross-feeding and dietary fibers.
Huge thanks Janina and to co-authors
#gut #microbiome #fibers #prebiotics
https://t.co/5ipIPemf0o

[Microbiome Research Reports @MicroResRep]

Out of the oven! Galacto-oligosaccharides alone and combined with lactoferrin impact the Kenyan #infantgutmicrobiota and epithelial barrier integrity during iron supplementation in vitro
https://t.co/AX7lXQA0dT
#Gutmicrobiome #micronutrient #prebiotic
Welcome to read and share!

[Marc Erhardt @Salmo_Lab]

Our work describing the structure and mechanism of the Zorya anti-phage defense system is finally out @Nature! Led by @HaidaiHu and @__jphilipp in a wonderful collaboration with @NMITaylorLab, @SimonJacksonNZ, @AHarms485 et al.!

https://t.co/xCXVEqfJv3

[Petra Zimmermann @Dr_Petzi]

Did you know that your gut bacteria produce melatonin? #Melatonin is not only important for your sleep but for almost every organ in your body. Read more https://t.co/86uSLx3VE6
Thank you @KurthSalome, Benoît Pugin and Nicholas Bokulich for your collaboration.

[Benoit Pugin @BenoitPugin]

@HausmannAnnika @PascaleVonaesch @ETH @Slack1Emma @y_efis @syis_ecr Congratz Annika !

[Clavellab @clavellab]

10 days left to apply and join the lab 🔥 Great team spirit 💫 https://t.co/DXvX6cQmQv @UniklinikAachen. Personalised syncoms of cultured gut bacteria in gnotobiotic mice 👇 https://t.co/tyIpN1NuhL

[Randall Platt @randall_platt]

🚨Job alert🚨 We are recruiting a postdoc to develop and apply in vivo single-cell CRISPR screening methods. This builds upon our recent AAV-Perturb-seq work (https://t.co/u1MEwNdJVh).

Come join us in Basel, Switzerland! More info at: https://t.co/XooqwVsg0f

[Clavellab @clavellab]

The lab is recruiting (postdoc level) 👇 Join us: we love good science and there is a great team spirit 💫 https://t.co/DXvX6cQUG3; https://t.co/alwHJIilpK

[Microbiome Research Reports @MicroResRep]

Latest Publication🥳
A pilot case-control study on the #fecalmicrobiota of #pediatric functional abdominal pain-not otherwise specified and the role of early life stress
View: 👇https://t.co/YUvMCPThMx
#fecalmetabolites #earlylife stress
Welcome to read and share🤗

[Communications Biology @CommsBio]

A study on early life traumatic stress in mice suggest that changes in the fecal microbial community induced by early life stress can be perpetuated from an exposed parent to the offspring across two generations.
@BenoitPugin @IsabelleMMansuy
https://t.co/hZI17OeZXX

[Florin-Dan Popescu @FlorinDanPopesc]

#eaaci2024 Awards @liam_OMahony1

[APC Postdoc Association @APCPostdoc]

Join the online APC forum next Tuesday to listen to @BenoitPugin 🦠🩺 It will be followed by a Q&A session for early career scientists 🥼 @Pharmabiotic

[Emma Slack #IStandWithUkraine @Slack1Emma]

2 weeks left to apply! Are you a budding immunologist who likes to work across disciplines 🧬🧫🔬🧪? We would love to hear from you.
@Dunn_School

https://t.co/7c29rMgMJL