How does a DNA repair enzyme find a needle in a haystack? 🧬
Our latest paper in NAR, led by the one and only C-trap queen @kaitlindehart, uses single-molecule imaging to watch APE1 scan DNA and lock onto AP-sites. @LUMICKS_US
https://t.co/as3AS26Cwy
This past weekend we hosted the 25th annual Midwest DNA Repair Conference at KUMC. Got to hear about a lot of great science going on and caught up with some friends. (Happy to say I won best post-doc poster as well).
Try this new online training game from Leandro F. Estrozi designed for newcomers in structural biology, with a focus on cryo-EM and cryo-ET map interpretation: https://t.co/gxhQXmRPWL
Grateful to host Sen. @JerryMoran and @NIHDirector_Jay in the Freudenthal Lab today. I’m incredibly proud of our trainees, who showcased their work using the @LUMICKS_nl C-Trap and the KU Cryo-EM Facility. Their dedication highlights how federal investment drives discovery and cancer research at @KUcancercenter.
Great way to end two summer student internships with the @KUcancercenter symposium. Fantastic work by Carson Gray (undergrad) and Esther Solange (high school student)!
Kudos to @abbey_vito, @peyton_oden, and @Biochem_Ling for being wonderful mentors.
The #EMGS is pleased to announce the winner of the 2025 Samuel H. Wilson Award for Studies on DNA Repair, Dr. Mark Hedglin, PhD!
Don't miss his presentation, "Rad6 Is Dynamically Accessible for Activation Within the Rad6(Rad18)2 Complex: Mechanistic Insights into a Ubiquitin Cascade Critical for Human DNA Damage Tolerance" at #EMGS2025 in Platform 1 on Sunday, September 7th.
https://t.co/6HEAmISMvN
My lab at UVA is looking to hire a Postdoc to study mechanisms of DNA repair in chromatin using biochemical, biophysical, and structural biology approaches!
Feel free to share with anyone you think may be interested.
https://t.co/iEbZEIp7ac
Discovery of the chromatin structural determinants of 8-oxoG repair and the mechanisms of repair of KBrO3-induced 8-oxoG-induced mutations. https://t.co/aTRRw9yjRP #CancerResearch @natrescancer
Excited to share some really cool work I was apart of (with @tylermweaver1) during my post doc in the @Freudlab. Was a really great collaboration!
https://t.co/KYELSSJJ7x
Excited to share the final piece of my postdoctoral work (with @benny_ry) in the @Freudlab, where we determine the kinetic and structural basis of gap-filling DNA synthesis in the nucleosome by Pol β. https://t.co/IE0LdG4Mc1
The Vandy goalpost traveled almost 3 miles to get to the Cumberland River 🔥😳
From tearing it down to ending up in the river it only took @VandyFootball fans a little over an hour to get the job done 🤯