HUPO Human Brain Proteome Project (HBPP)

Official account of the @hupo_org HBPP. Using proteomics to unravel the mysteries of psychiatric, psychological, and neurodegenerative disorders.

[HUPO Human Brain Proteome Project (HBPP) @BrainProteomics]

Welcome to the new official X account for the @hupo_org #HBPP. If you have any research articles, news, or events related to 🧠 #proteomics that you'd like us to feature, please tag or DM us. Feel free to give us a follow and spread the word!

[Darragh O'Brien @darraghpobrien]

Had a great time representing the @hupo_org Human Brain Proteome Project at the "Friends of HUPO" social at #HUPO2025 last night. If you want to hear more about the initiative, or get involved, please get in touch 🧠

[Alzheimer's Association @alzassociation]

There’s still time to be part of what’s next in neuroscience! Abstract submissions for AAIC Neuroscience Next (Feb. 23-26) are open now until Oct. 22 for students and early career investigators. Learn more: https://t.co/4uXQ9hpy6O. #AAICNeuro

[Yale Department of Genetics @YaleGenetics]

New research using the world’s largest neurodegenerative proteomics dataset reveals how APOE ε4, a major genetic risk factor for Alzheimer’s, also drives inflammation linked to Parkinson’s, ALS, and other brain disorders. Check out this article: https://t.co/v7Rwlkv3GI

[Brain @Brain1878]

Using CSF proteomics, Tijms et al. identify three Alzheimer’s disease subtypes that show: 1) hyperplasticity and increased BACE1 levels; 2) innate immune activation; and 3) blood-brain barrier dysfunction with low BACE1 levels. https://t.co/O1O1mO9N1l

[yaroslav markov (he/him) @MarkovYaro]

🧠 New preprint from my PhD work at Yale!

We explored how the APOEε4 allele — Alzheimer’s strongest genetic risk factor — shapes molecular pathways across DNA methylation & proteomics in the brain.

https://t.co/qOJnpAjDij

[YSM Pathology @yalepathology]

Nicolas Fawzi, PhD, Professor @BrownUniversity, presents today at 3 PM @YaleMed on “Dynamic Atomic Structures of RNA-Binding Protein TDP-43 – Drug Targets for ALS & Neurodegeneration” #Dementia #AlzheimersDisease https://t.co/OeWk4RSAMl

[Brain @Brain1878]

Karlsson et al. show that normalizing AD CSF and plasma biomarkers to reference proteins increases their agreement with tau- and amyloid PET, enhancing the accuracy of fluid biomarker tests for detecting pathological changes. https://t.co/uAK0GB1W48

[FENS @FENSorg]

🌟 Call for #FENS2026 Social Media Ambassadors!

💭 Are you passionate about #neuroscience and active on social media?
We are looking for enthusiastic Social Media Ambassadors to help promote the #FENSForum!

🗓️ Deadline: 14 November 2025
👉 https://t.co/KPbDivZ6TM

[Society for Neuroscience (SfN) @SfNtweets]

The right support makes all the difference.

The Neuroscience Scholars Program offers mentorship, career resources, and a network invested in your success.

Find out more about the new expanded eligibility & submit your application today.

🔗 https://t.co/IhRm5PVvtD

[Human Proteome @hupo_org]

📣The HUPOST August 2025 issue is here!
📷Featuring: 2025 Congress Updates, News from ECR Committee, & Much More!
https://t.co/OdrRPh1dEW

[Science Advancement and Outreach @SAOscience]

New neurodevelopmental research from @UTSWMedCenter 🧠

The @buszczaklab used human cerebral organoids, proteomics, single-cell RNAseq, & more to uncover molecular drivers of developmental defects tied to certain genetic variants.

https://t.co/8s5OBfNR71

[Yale/NIDA Neuroproteomics Center @Neuroproteome]

The NIH grant application to fund the Yale/NIDA Neuroproteomics Center through April 2030 has been awarded! We’re deeply grateful to our pilot project applicants, Research in Progress speakers & attendees and colleagues; your support has helped make this achievement possible.

[Nature Medicine @NatureMedicine]

Analyses from the largest neurodegeneration focused proteomics database - the Global Neurodegeneration Proteomics Consortium @_neuroproteome are published today in @NatureMedicine and @NatureAging

The findings reveal unique protein biomarkers that correlate with @neurodegenerative diseases and the @ageing process, and may help with the early detection, and improve outcomes, of major neurodegenerative diseases.

Read the collection here: https://t.co/TZuP4teWvd

[Nature Medicine @NatureMedicine]

🔆AUGUST ISSUE 🔆

Read about #research from the Global Neurodegeneration Proteomics Consortium (GNPC), which provide insights into #proteomics changes and potential #biomarkers & drug targets for neurodegenerative diseases.

#neurotwitter #brainhealth

https://t.co/x0YCeh94pA

[FENS @FENSorg]

@EJNeuroscience @WileyGlobal 💭 Curious about other FENS2026 Awards and Prizes?
🔗 Explore all opportunities: https://t.co/EDzzO4aurk

[Human Proteome @hupo_org]

#HUPO2025 Gala Dinner Theme - “Modern Science, Vintage Glam”

Join us for the HUPO Gala Dinner at The Carlu, a restored Art Moderne icon for live jazz, elegant dining, dancing, and 1920s vintage flair! 🎤🎷

📅 November 12, 2025, The Carlu, Toronto
👉 https://t.co/bZYDo9HpWB

[Human Proteome @hupo_org]

Friends of HUPO Reception Reminder! ⏰

If you want to be considered for having a poster during the Friends of HUPO Reception on Monday, November 10 then submit a brief overview of your work by Friday, September 12.

Deadline: Sept 12, 2025
Submit Today: https://t.co/43yJelq530

[The Science of Parkinson's @ScienceofPD]

Interesting:
@_neuroproteome researchers looked at proteomics data from 11,270 individuals & find a conserved APOE ε4-associated pro-inflammatory immune signature persistent across the brain, CSF & plasma irrespective of neurodegenerative conditions
https://t.co/M7MoGMqjsV

[sciqst @sciqst]

The research on spatial proteomics to identify Alzheimer’s-specific microglial states provides fascinating insights into the intricate role of microglia in brain health. Understanding these unique states could be key in developing targeted therapies for neurodegenerative disorders. Are there particular microglial markers that stand out in your findings for therapeutic potential? For those interested in diving deeper or generating detailed biomedical reviews on emerging neuroimmunology topics, check out https://t.co/4Y9Imt8uIJ. It's a powerhouse resource for your biomedical queries. #Neuroimmunology #Medicine #Bioinformatics

[Biomedicines MDPI @Biomed_MDPI]

#recommendedpaper 🍡
Today's recommended article is as follows:🥂
Title: Next-Generation Proteomics of #Brain Extracellular #Vesicles in Schizophrenia Provide New Clues on the Altered Molecular Connectome
Check it out:🎰
https://t.co/RbAaUpXPvG
@MDPIOpenAccess @MDPIBiologySubj