Excited to share the first research paper from our team deposited on bioRxiv https://t.co/ILJoSD7NYD. Our study harnesses a natural-product inspired electrophile for covalent protein modification. Led by amazing postbacs with tremendous help from proteomics core @NCIResearchCtr
Our department has grown quite a bit over the last year. We have one group leader position remaining- Principal Scientist, Interactomics. If you are interested in developing and applying cutting edge proteomics research to therapeutic discovery apply here: https://t.co/yB3JAOG0LS
My team has a postdoctoral position open at Genentech in Infectious Disease focused on the development and use of chemical biological approaches in microbiome research. If interested, please see: https://t.co/jmNjVVZ1xL
Open position in our biophysics group. A great opportunity to make an impact in small molecule drug discovery. No PhD required.
https://t.co/tNmIL8exRK
@Chemjobber#chemjobs#biotech
Congratulations to team Saki @hopeflaxman @Big_Fish_Linda @nandinivsr Hannah Dacheng and collaborators @MattRPratt and Binyou! This was a true collaborative effort in the group to discover a degron for cereblon! https://t.co/rjepqtWf2n
So excited to finally be sharing this story!! Thank you to the many collaborators (including @taylorhnguyen in KC Huang's lab, the teams of @ajodonoghue, @MJNiphakis and Ami Bhatt, and my mentor @MLakeme) for helping me and @mbogyo bring this story to life!
Our first paper on our efforts mapping serine hydrolases in gut commensal bacteria is out. We identified a homolog of the human DPP4 protease in B. theta that is important for community fitness. https://t.co/24vXeHnAJ6
Excited to see this cryoEM of Pseudomonas aeruginosa RNAP! With my favourite regulator, SutA! Thanks to Yu Zhang, Yu Feng and colleagues for this very cool work.
https://t.co/GwfJkDJdoH
Honored to see our work on ABPP-aided Mtb inhibitor discovery and characterization back to back with @mbogyo@BrettMBabin in excellent company in this special issue. Thanks, @CellChemBiol!
Open access: https://t.co/IpJTNP07aJ
Our #biophysics group at #Genentech is #hiring at the Sr/Principal Scientist level. Exciting opportunity to join a great group of colleagues working on challenging small molecule drug discovery projects.
Reach out if you have any questions about the role. https://t.co/oxOopxWCKA
Excited to share our paper now out in @NatureMicrobiol https://t.co/eIwZzabeI7. We used our CG screening and clinical Mtb genomics method to reveal novel mechanisms of drug resistance and identify a new opportunity to potentially use clarithromycin in TB treatment
Excited to share our lab’s latest research article led by @FelipeB_dAndrea and @NickPoulton6, now on @ScienceAdvances. In this work we dissected the in vivo contributions of the essential caseinolytic protease subunits, ClpP1 and ClpP2, to M. #tuberculosis growth and pathogenesis
Pls RT: I’m hiring! 🎉 Now opening a Scientist position (!) at Genentech to build 3D cultures of the TME.
Intended to provide industry exp for new PhDs/PDs that want to learn drug discovery. 1 yr contract.
Benefits:
-$120-130k salary
-health ins
-401K
-mentorship
#Postdoc position in our group at Genentech. This is a great group and a great environment for learning from our combined expertise in SPR, mass spectrometry, and other biophysical techniques. #postdocjobs Quinn Lab https://t.co/SMYrGCuQAJ
Some scientific illustrations become memes*, some turn into cultural icons.
It requires a combination of originality, aesthetic, simplicity and scientific accuracy.
Here are some of them 🧵
1/n
*memes in the original sense: units of cultural inheritance that replicate and evolve
Not many Keystone conferences have a strong chemical biology focus but this one does: https://t.co/8Y0zRMiczb. Please retweet as I think it features a mix of #chembio and pharmaceutical speakers. #chemtwitter