9 new structures this week for a total of 223 SARS-CoV-2 PDB structures available for exploration: https://t.co/C8psgBQVrw June's Molecule of the Month looks at how the coronavirus spike protein binds to receptors on cell surfaces https://t.co/Ou89JXYEbm
Keep Physical Distance far ↔️ but Social Bond Close and Strong 👍: Non-Covalent Molecular Interaction. ⚗️ #MedChemInfo For higher resolution image and references please visit ➡️ https://t.co/slZC8xeUYT ⚙️ made @ChemDraw.
Immunology of #COVID19 | Mechanisms of host innate immune response and coronaviruses antagonism | Robert Samstein @IcahnMountSinai The Sinai Immunology Review Project @ImmunityCP https://t.co/BjM7VxLg0y
A recurrent mutation of the Spike #virus protein (D614G) is spreading in Europe and becoming the dominant form of the virus. This observation has important implications for the transmission of #SARSCoV2 and the design of the #vaccine: https://t.co/mHHzUDciw3
#COVID19#pandemic
Minireview: https://t.co/2aXL2OVZGT (OPEN)
"Targeting the 'Cytokine Storm' for Therapeutic Benefit" by
Riccardo V. D’Elia, Kate Harrison, Petra C. Oyston, Roman A. Lukaszewski and Graeme C. Clark https://t.co/NGt3xvQkCk
What makes a drug discovery consortium successful? https://t.co/kXUclvE483 This new article from Peter Simpson and Graeme Wilkinson @MedDiscCat discusses some key factors
While clinical trials are ongoing to determine the safety and effectiveness of hydroxychloroquine and chloroquine for #COVID19, there are known side effects of these medications that should be considered. https://t.co/eFURIsAeX2
RESEARCH ARTICLE: https://t.co/rCR1qDkVNM (OPEN)
"Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease" by Wenhao Dai, Bing Zhang, Xia-Ming Jiang, Haixia Su, Jian Li, Yao Zhao, Xiong Xie, Zhenming Jin, Jingjing Peng,…https://t.co/SKfre83MLa
#BekalPulang:
Ketika kita ditanya tentang bunda Hajar (ibunda Ismail as) dan rindu berusaha ketemu diakherat. Apa yang kita imani ?....
Jawab: Qs. 2.158...
....Sesungguhnya Alloh Syaakirun 'aliim.
Article: https://t.co/9jpxsjvO4Y)
"High-yielding continuous-flow synthesis of antimalarial drug hydroxychloroquine" by Eric Yu, Hari P. R. Mangunuru, Nakul S. Telang, Caleb J. Kong, Jenson Verghese, Stanley E. Gilliland III, Saeed Ahmad, Raymond N. Domine…https://t.co/1F4mKX6jnJ
Article: https://t.co/MYlCVQ1R8X (OPEN)
"The FDA-approved Drug Ivermectin inhibits the replication of SARS-CoV-2 in vitro" by Leon Caly, Julian D. Druce, Mike G. Catton, David A. Jans and Kylie M. Wagstaff https://t.co/GWRmiKkrmX
My illustration of SARS-CoV-2's trimeric spike glycoprotein, based on available PDB structures. The Spike protein initiates binding and fusion with the human host cell and is a major target for antibody research. #covid19#SARSCoV2#sciart