Caleb Glassman

Genetics Gaucho/Viral Vaquero with Steve Elledge (Post-Doc)
Former Cytokine Cowboy with Chris Garcia (Grad)
Signaling aficionado but an absolute bozo otherwise

[Caleb Glassman @CalebGlassman]

Despite their diverse routes to degradation, viral ubiquitin ligases convergently target key nodes in immune signaling like JAK1 and CUL1–β-TrCP underscoring the importance of these pathways in viral restriction.

[Caleb Glassman @CalebGlassman]

We have a new paper online today at @ScienceMagazine! We applied our recently developed library of viral open reading frames to discover and characterize viral ubiquitin ligases. https://t.co/HNKjw5oDzd

[Caleb Glassman @CalebGlassman]

We find that viruses exploit the modularity of the ubiquitin-proteasome system in unique ways, but these mechanisms often rhyme with the underlying logic used by the host.

[abby monteil @abbyemonteil]

no more “girl math.” that’s how we got the bene gesserit

[Erika Alden DeBenedictis @erika_alden_d]

An essay I wrote with @NikoMcCarty on the upcoming age of AI x Bio.

"The next century of biology will be a coordinated, whole-field effort to divide biology into a series of prediction tasks and then solve those tasks, one-by-one."

[typedfemale @typedfemale]

met a grad student doing a natty phd tonight. no coffee, no amphetamines, no meal replacements

[Caleb Glassman @CalebGlassman]

Brilliant work from @1987NT on an important and challenging cytokine!

[Cell @CellCellPress]

Now online! Structure of the thrombopoietin-MPL receptor complex is a blueprint for biasing hematopoiesis https://t.co/SV5QcT2EGW

[Caleb Glassman @CalebGlassman]

A ubiquitin-independent pathway for protein degradation with important implications for signaling. Congrats @ChrisNardone95 and @XinGu0317! It's been fun watching y'all figure this out. https://t.co/6bmBcvZrcV

[Caleb Glassman @CalebGlassman]

A must read for people interested in protein protein interactions. Way to go @aerin_yang Kevin and team!

https://t.co/nQ3d9q59HU

[Peter Bruno @petes_tweets0]

Next week I'll be starting my own lab at UCSF @UCSFUrology! We’ll be using synthetic biology and functional genetic screens to understand antigen presentation and T-cell recognition in cancer and other diseases. We’d love for you to join us! More info at https://t.co/90yf61qNRx

[Caleb Glassman @CalebGlassman]

A very important contribution to receptor assembly and signaling of gc #family cytokines. Go Gita!

[Gita Abhiraman, MD, PhD @GitaAbhiraman]

Excited to share my first paper from my PhD research in Chris Garcia's lab! We determined structures of the IL-21 receptor complex and engineered IL-21 variants that enhanced vaccine responses in tonsil organoids with reduced autoantibody induction. (1/9)
https://t.co/5fg5oGVBtn

[Stanford Immunology @stanfordimmuno]

Congrats to Dr. @GitaAbhiraman in successfully defending her thesis today on "Modulating immune signaling with engineered cytokines." 👏🎉 Great work!

[Caleb Glassman @CalebGlassman]

@DrJuanLMendoza Way to go, Juan!

[Juan L. Mendoza @DrJuanLMendoza]

Thank you, Leslie and everyone at HHMI. I can’t express how grateful I am to be part of this outstanding group of scientists. With the support of HHMI, we can focus on our science but also make an impact in mentoring to lift us all up. Congrats to all the FHScholars!

[Caleb Glassman @CalebGlassman]

The prophecy has been fulfilled!!!

[Stanford Immunology @stanfordimmuno]

Congrats to Dr. @amycfanphd for successfully defending her PhD thesis on “Genetic blood disorders and inflammation: Characterizing cell autonomous & non-autonomous contributions of RUNX1 loss in hematopoiesis and leukemogenesis” 👏🎉!! #StanfordImmuno #thesisdefense #PhD

[Caleb Glassman @CalebGlassman]

A major contribution to antibody recognition. Congrats Ellen, Steve, and Friends! https://t.co/F96xOKnmVG

[Addgene @Addgene]

The Human Cell-Surface Interactome Project, deposited by Chris Garcia's lab, is now available

https://t.co/JSxY4lbf51

[Utpal Pal Lab @PalLabUMD]

Excited to share our discovery of a new twist in host-pathogen interactions, published today in @ScienceMagazine! https://t.co/m047U6cncr

[Caleb Glassman @CalebGlassman]

What an honor! I never met Hugh but my advisor, Chris Garcia, always spoke very highly of him. 🤠

[Stanford Immunology @stanfordimmuno]

Congratulations to @CalebGlassman for being the 2022 Stanford Immunology McDevitt Award winner for his dissertation on Structure-Based Cytokine Engineering. I don't have a photo of Caleb, so I am using the photo from his hybrid defense.

[Dirk H. Siepe @dhsiepe]

Such an amazing story, kudos @XinboYang777 and the whole team