Dana-Farber Center for Patient Derived Models

Research center working towards #precisiononcology. Ask us about generation, characterization & applications of patient-derived models (PDX, organoids, cells).

[Dana-Farber Center for Patient Derived Models @CancerModels]

CPDM's work and our recent Nature Biomedical Engineering paper were featured on https://t.co/kXMLO9maar: https://t.co/5QWH0ganay

[Dana-Farber Center for Patient Derived Models @CancerModels]

Are you joining us in Copenhagen for the first meeting to unite genomic and functional precision medicine? Find out more https://t.co/wr2byOzMJV

[Dana-Farber Center for Patient Derived Models @CancerModels]

Podcast: AI and Organoids Show Promise for Glioblastoma Patients - UHealth https://t.co/VzwCvQ4CXe

[Andy Lane @lane_andy]

Thrilled to share our latest work out today @Nature . A collaborative effort with many great, super smart colleagues, especially @gryfyndor @hovestadt @vangalenlab : https://t.co/t0JdgOrJGw

[Dana-Farber Center for Patient Derived Models @CancerModels]

Nice new review of #fpm https://t.co/rhENtQJLG5

[Dana-Farber Center for Patient Derived Models @CancerModels]

Congrats Maria on a fantastic undergrad thesis defense in #glioblastoma functional precision medicine at CPDM. Way to get honors! We were so proud and happy to have you with us & mentors Kin Hoe Chow, Sonam Bhatia, Smitha Yerrum and @KeithLigon5 @NeurosciBU #gpn @BU_Tweets #fpm

[Dana-Farber Center for Patient Derived Models @CancerModels]

@JacobRozowsky @nyugrossman Congrats!

[Dana-Farber Center for Patient Derived Models @CancerModels]

Great to see #fpm growing this year to have a whole session at #AACR2023 with exciting prospective trials results and other studies from @CancerModels collaborator @DrTonyLetai as well as Pam Becker and @AlanaWelm @PhilippStaber

[The Society for Functional Precision Medicine @TheSFPM]

Our @TheSFPM president, @DrTonyLetai, starts with a great introduction on functional precision medicine opportunities and challenges #AACR23 #FPMatAACR23

[Dana-Farber Center for Patient Derived Models @CancerModels]

Great meeting of the MassMinds!

[MassBio @MassBio]

President Biden said, "The goal is to cut cancer death rates by at least 50% in the next 25 yrs." This reignited Cancer Moonshot in Boston last September. Register for #SOP23 & explore the opportunities & barriers to realizing this ambitious goal. https://t.co/8Jez5spZS6

[Dana-Farber Center for Patient Derived Models @CancerModels]

Great to see functional precision medicine now getting BigPharma attention #fpm #precisionmedicine #oncology #cancermodels

[Nature Reviews Drug Discovery @NatRevDrugDisc]

Mini-organs attract big pharma https://t.co/YVM61aL9l9

Hans Clevers, head of Pharma Research & Early Development at Roche, discusses the role for organoids in drug discovery and development in this new interview

[The Society for Functional Precision Medicine @TheSFPM]

Join us *THIS WEDNESDAY* March 8th at 11:30 AM EST / 8:30 AM PST for our next seminar featuring @ElementoLab from @WCMEnglanderIPM presenting "From reading genomes to patient avatars - the future of personalized medicine".
Link/Info available here: https://t.co/ohnuFm7onq

[Dana-Farber Center for Patient Derived Models @CancerModels]

A subset of models from CPDM can also be browsed here https://t.co/t2xHMATPVm

[Dana-Farber Center for Patient Derived Models @CancerModels]

for all creators and users of cancer models please fill out this user survey for @CancerModelsOrg

[CancerModels.Org @CancerModelsOrg]

Calling all users of cancer models and cancer models data - please fill out our 5-minute user survey: https://t.co/s7gwXeblZP
We want to hear from you! #CancerResearch #oncology #PrecisionMedicine

[Dana-Farber Center for Patient Derived Models @CancerModels]

also, check out their massive effort of curating information from a whole host of cancer models. https://t.co/vsaW8vwdbb

[Dana-Farber Center for Patient Derived Models @CancerModels]

Check our highly collaborative effort with wonderful colleagues and lots of patient-derived models!

[Keith Ligon @KeithLigon5]

Our new paper w/BMS shows CAFs are the source of EMT signal in most cancers --> data from 333 PDX models/11 tumor types from @DanaFarber @CancerModels. Thx Michael Tolstorukov's DFCI I/A team, @Novartis, and David Weinstock for helping CPDM make the models available to the science community. @bmsnews https://t.co/z8I1G5TUL5
https://t.co/L9lOXnorlG

[The Society for Functional Precision Medicine @TheSFPM]

Attending #AACR23 in Orlando this year? Save the date and Join us for a fun night of food, drinks, and networking. This is a great opportunity to learn more about the SFPM, meet the board, share ideas and even become a member! RSVP on https://t.co/oKQNcPb5zo

[MIT Technology Review @techreview]

On average, it takes more than 10 years and billions of dollars to develop a new drug.

Incorporating AI into the drug development pipeline could help create cheaper pharmaceuticals faster. https://t.co/xYVZFyA5fY

[Eric Vallabh Minikel @cureffi]

If an ASO lowers target RNA 50% in bulk brain tissue, is it 50% in all cells or 100% in half? Are cell types all impacted equally? Does CSF reflect neuronal target engagement?

We did single-cell seq in ASO-treated mice & NHPs to find out https://t.co/2rR8ICVm0s

Thread 👇

[Dana-Farber Center for Patient Derived Models @CancerModels]

Handing off the weekend work to the #robots! Feat. #aligent #biospa

[Glioma Genomics Research Group @GliomaGenomics]

We think we've found something v.interesting 🧐:IDHwt GBMs can be stratified by treatment response which might inform targeted therapies. Read our study here: https://t.co/VHp0numYEV Funded by @UKRI_News @BRUKresearch @DiMeN_Diversity @LDShospcharity @OscarsCharity @YorkshireBTC