Remembering Karenna Groff.
I met Karenna on the first day of medical school orientation and we bonded over our mutual interests in neurosciences and oncology, and Boston upbringings. We immediately became best friends. 1/5
Colorectal cancer rates are falling in adults over 60, but among adults under 45, the disease is rising.
Mia Petljak, PhD, is studying tumor DNA for mutational signatures linked to plastic exposure to better understand whether microplastics may be contributing to the trend. ⤵️
I’m incredibly grateful to @psscra for the Pershing Square Sohn Cancer Prize, recognizing our work and enabling an important part of our broader vision to develop personalized cancer prevention strategies 🙏
Congratulations to Mia Petljak (@DRMP2025) @Perlmutter_CC on being awarded a @psscra Cancer Prize!
Mia’s proposal focuses on the mutational signatures of microplastics in cancer, including early onset cancers. And she made the announcement cover!
https://t.co/mgtOJ9ZvqE
🚨🚨🚨
RASOLUTE-302 Ph3 is POSITIVE
"Daraxonrasib demonstrated a median OS of 13.2 months versus 6.7 months for chemotherapy, with a hazard ratio of 0.40 (p < 0.0001)".... WOW!
AMAZING news for patients with #PancreaticCancer
The RAS Revolution is ON!!
https://t.co/I59NNWRB1O
‼️Next up: We introduce our newest class of @UCSFPlastic Surgery residents. Four future surgeons who've matched into one of the most competitive training paths in #medicine. Join us in welcoming the newest members of our Plastic #Surgery family✂️ #Match2026
Thrilled to share our latest study on pediatric ependymoma, out in @Nature! Biggest congratulations to all members of our international team, especially the labs of @VarunVenkatara2 and Kristian Pajtler, and fearless leader in my lab, @DaeunJeong10. @DanaFarber@BostonChildrens
Where do cancers start? In the liver, not all cells are the same. The liver is divided into 3 “zones,” and each specializes in different metabolic tasks. We show in @Science that where a mutation occurs in a liver lobule can determine a cell’s fate. https://t.co/3YTc77gZcd (1/9)
Big, beautiful trees!!
SMART-PTA for whole-genome+transcriptome on thousand of single cells from the normal human esophagus 🤯 Massively scaling up the power of scWGS to build deep phylogenies and chart somatic evolution from birth throughout life.
https://t.co/pciw5yME0x
Grateful to the many teams who supported this work, championed by Karenna Groff. As we uncover more biomarkers of tumor behavior, implementation into clinical practice merits close introspection of context. @MGBneurosurgery@LabRaleigh@sahm_lab@MGBCTNS@NYUneurosurgery@RuchitVP
I mourn not just for myself and my friends, but for the lives she would have saved and the people she would have loved. May her memory be a blessing. 5/5
Remembering Karenna Groff.
I met Karenna on the first day of medical school orientation and we bonded over our mutual interests in neurosciences and oncology, and Boston upbringings. We immediately became best friends. 1/5
She was so much more than a talented future-physician, scientist and athlete. Karenna loved people and humanity, and I am so lucky to have been loved by her. I can still hear her infectious laugh, see her dimpled smile, and feel her hugs that took my breath away. 4/5