Cardiac Insight UK

Heart and Circulatory Disease Prevention Promotion Platform. Hosted by Julian Halcox MD FRCP Professor of Cardiology, Swansea University Medical School

[INOCA INTERNATIONAL @InocaInternati1]

The INOCA Journey is often longer and more difficult than even the most experienced medical professionals sometimes realise. Just imagine the additional patient and healthcare costs that are associated with the example below and sadly this is not unusual🫤
https://t.co/GtsisGl3Kj

[INOCA INTERNATIONAL @InocaInternati1]

Professor Filippo Crea shares 3 of the reasons why the guideline directed steps forward in the recognition investigation, diagnosis and treatment of INOCA conditions are so important. https://t.co/VogV8kWCXA

[Cardiac Insight UK @CardiacInsights]

@VJNeurology @UNSW Warning! Not yet a strategy for routine practice. Great study, but remember ischaemic is far more common than haemorrhagic stroke, precluding indiscriminate use of this prehospital Rx strategy in acute stroke, without definitive confirmation of aetiology.

[Dr Paddy Barrett @Paddy_Barrett]

Why does high blood pressure matter?
⬆️ Risk Of Kidney Disease
⬆️ Risk Atrial Fibrillation
⬆️ Risk Of Heart Attack
⬆️ Risk Of Dementia
⬆️ Risk Of Stroke
⬆️ Heart Failure

For every 20mmHg ⬆️ in systolic blood pressure, the risk of dying from a heart attack & stroke - Doubles!

[Cardiac Insight UK @CardiacInsights]

@ProfKausikRay Great work Kosh and team!

[Cardiac Insight UK @CardiacInsights]

@KetoCyclist @Drlipid Start by reading this paper and follow the citing articles https://t.co/mVGolRIUv4

[Cardiac Insight UK @CardiacInsights]

@AsarCadyn @Drlipid @doingnz Increasing endothelial permeability to #ApoB Lps as well as promoting leukocyte attraction, adhesion and infiltration

[Cardiac Insight UK @CardiacInsights]

@AsarCadyn @Drlipid @doingnz Important influence of local #Shearstress conditions (low/oscillatory/differential) promoting #endothelialdysfunction at bifurcations and in curved sections of high flow conduit arteries (esp coro & carotid)

[LipoFan @lipo_fan]

"THICKENING may be regarded as a prerequisite for RETENTION AND ACCUMULATION of lipids and thus for plaque formation.

B-48 and B-100 was found to be positive either in cases with greater expression over the THICKENED INTIMA or in the AREA AROUND THE INTIMA–MEDIA transition(4C)"

[Dr Paddy Barrett @Paddy_Barrett]

Exercise is probably the single best way to extend lifespan.

You need to exercise like your life depends on it.

Because it does.

Here's why.

📕Make Sure To Bookmark✅

🧵👇
/1

[HEART UK @heartukcharity]

Did you know? 92% of HCPs who attended our webinars reported being ‘much more’ or ‘more’ confident treating their patients for high cholesterol because of attending.

https://t.co/yO2mHuoVg0

[Cardiac Insight UK @CardiacInsights]

@sunsopeningband @MECFSNews Could this underpin sympathetic NS activation ultimately leading to the #dysautonomia we see so commonly in patients referred to us for cardiac opinion?

[Todd Davenport @sunsopeningband]

Mitochondrial dysfunction still persisted after SARS-COV-2 was cleared, so viral persistence wasn’t the mechanism in this study. Instead, reduced ATP production was due to altered mitochondrial gene expression.

tl;dr: Viruses teach good beans bad tricks. https://t.co/tm9vA57G9j

[Pablo Corral MD @drpablocorral]

👉The relationship between genetic liver fat and coronary heart disease is explained by apoB-containing lipoproteins

☝️In conclusion, here we found 25 independently liver-fat associated SNPs.
We observe that SNPs that increase, decrease, or have neutral effects on apoB-containing lipoproteins result in corresponding increases, decreases, or neutral effects on CHD risk.
Therefore, the impact of genetically-driven liver fat on CHD is explained by its influence on apoB

https://t.co/OrAnF8Hc1J

@ATHjournal
@society_eas

[DrSarahJarvis @DrSarahJarvis]

New survey data has found that two in five people (42%) wouldn’t make a GP appointment if they noticed a change in their body that they thought could be cancer. Don’t carry the worry of cancer with you, speak to your GP. For more information visit https://t.co/5qRN6qpf3p

[Atherosclerosis @ATHjournal]

Women are at decreased 🫀 risk compared to men until menopause, an effect not solely explained by estrogens. In case you missed it, read the article by @jasminenour7 @fabri_bon87 @DaniloNorata in our Journal!
@society_eas @EASCongress
🔗https://t.co/ezItvXZsHn

[ACC Media Center @ACCmediacenter]

New research indicates that adults had a decreased #CVD risk if they ate foods associated with the Mediterranean diet. Read more in @EndocrineToday: https://t.co/gTgpzd0O8n #cvPrev

[Cardiac Insight UK @CardiacInsights]

@bbchealth As a Cardiologist I’m seeing increasing numbers of #postCovid/post-Vax pts with orthostatic intolerance/POTS/inappropriate tachycardia. Some have #MACS. Where is the expertise to help manage the multi system dysfunction? Need greater investment in multidisciplinary services!

[Cardiac Insight UK @CardiacInsights]

@lipo_fan Need further corroborating studies

[Cardiac Insight UK @CardiacInsights]

@lipo_fan Compelling associations. Is it time to start direct measurement of LDL-C, to allow inference of TRL/remnant levels in routine practice?